Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Zhijiao Zhang"'
1
Akademický článek
Preliminary study on the potential impact of probiotic combination therapy on Helicobacter pylori infection in children using 16S gene sequencing and untargeted metabolomics approach
Autor: Ya Yan, Lingjun Dong, Juan Xu, Zhijiao Zhang, Pengyan Jia, Jingmin Zhang, Weihong Chen, Weiqi Gao
Publikováno v: Frontiers in Microbiology, Vol 15 (2024)
ObjectiveThe purpose of this study was to explore the potential mechanism of Helicobacter pylori (Hp) eradication by probiotic therapy through 16S rRNA gene sequencing technology and untargeted metabolomics.MethodsTwenty four Hp-infected children wer
Externí odkaz: https://doaj.org/article/3a38372f0b9a419292662c892b22b022
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2
Akademický článek
A clinical study of the correlation between metabolic-associated fatty liver disease and coronary plaque pattern
Autor: Zhijiao Zhang, Mengyao Zheng, Hongtao Lei, Zimeng Jiang, Yuhang Chen, Haiyu He, Gongfang Zhao, Hua Huang
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome (MetS) and has been correlated with coronary atherosclerosis (CAS). Since NAFLD was renamed metabolic-associated fatty liver disease(MAFLD) in 2020,
Externí odkaz: https://doaj.org/article/281e7a4abc844e64afcd89e75108ee1f
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4
Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability
Autor: Tong Zhao, Jian Zhang, Yucen Tao, Hui Liao, Fabao Zhao, Ruipeng Liang, Xiaoyu Shi, Zhijiao Zhang, Jianbo Ji, Ting Wu, Jianxin Pang, Xinyong Liu, Peng Zhan
Publikováno v: Journal of Medicinal Chemistry. 65:4218-4237
Lesinurad is a uricosuric agent for the treatment of hyperuricemia associated with gout, which was found lacking in efficacy and safety. Here, scaffold hopping and molecular hybridization were exploited to modify all the structural components of lesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e4f922e387c4ea3bfabcdb9cf6897c
https://doi.org/10.1021/acs.jmedchem.1c02057
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6
Design, synthesis and activity evaluation of novel lesinurad analogues containing thienopyrimidinone or pyridine substructure as human urate transporter 1 inhibitors
Autor: Jian Zhang, Yue Dong, Shenghua Gao, Xujie Zhang, Hui Liao, Xiaoyu Shi, Zhijiao Zhang, Tong Zhao, Ruipeng Liang, Danhui Qi, Ting Wu, Jianxin Pang, Xinyong Liu, Peng Zhan
Publikováno v: European journal of medicinal chemistry. 244
Urate Transporter 1 (URAT1) plays a crucial role in uric acid transport, making it an attractive target for the treatment of gout and hyperuricemia. As a representative URAT1 inhibitor, Lesinurad treat gout by promoting the uric acid excretion. Howev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175eb6f81f0724b3b25f880d19935bf2
https://pubmed.ncbi.nlm.nih.gov/36219903
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8
A Bayesian Network-based risk dynamic simulation model for accidental water pollution discharge of mine tailings ponds at watershed-scale
Autor: Jing Liu, Lixiao Zhang, Zhijiao Zhang, Yanpeng Cai, Renzhi Liu
Publikováno v: Journal of Environmental Management. 246:821-831
Mine tailings ponds that contain heavy metals are sources of potential risk to human security and ecosystem health. China particularly faces challenge of accidental water pollution risk from more than 8869 mine tailings ponds in serve by 2015, some o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5615234a4f65df5d9274a8ec4af45f8e
https://doi.org/10.1016/j.jenvman.2019.06.060
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9
Dual pH- and Light-Responsive Amphiphilic Random Copolymer Nanomicelles as Particulate Emulsifiers to Stabilize the Oil/Water Interface
Autor: Hui Duan, Zhijiao Zhang, Hui Liu, Feng Wang, Xiaoyun Yu, Zhouxiaoshuang Yang
Publikováno v: The Journal of Physical Chemistry C. 122:18995-19003
Dual pH- and light-responsive nanomicelles self-assembled from amphiphilic random poly(methacrylic acid-co-methyl methacrylate-co-7-(4-vinylbenzyloxyl)-4-methylcoumarin) (P(MAA-co-MMA-co-VM)) have ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f1d4152a10e95352e4ad79fbb62191a
https://doi.org/10.1021/acs.jpcc.8b05065
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10
Copula-based exposure risk dynamic simulation of dual heavy metal mixed pollution accidents at the watershed scale
Autor: Jing Liu, Zhifeng Yang, Zhijiao Zhang, Hanwen Zhang, Renzhi Liu, Yanpeng Cai, Sakari Kuikka
Publikováno v: Journal of Environmental Management. 277:111481
Most heavy metal exposure and pollution results from multiple industrial activities, including metal processing in refineries, and microelectronics. These issues pose a great threat to human health, ecological balance, and even societal stability. Du
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a356fa4e631a779563611e1e6d1f8ce
https://doi.org/10.1016/j.jenvman.2020.111481
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