Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zhijiang Yan"'
Autor:
Young-Kwon Park, Ji-Eun Lee, Zhijiang Yan, Kaitlin McKernan, Tommy O’Haren, Weidong Wang, Weiqun Peng, Kai Ge
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The SWI/SNF complex BAF and the histone H3K4 methyltransferase MLL4 (KMT2D) play critical roles in enhancer activation, however the interplay between them has remained unclear. Here the authors show that BAF and MLL4 are interdependent in promoting e
Externí odkaz:
https://doaj.org/article/fdd9c8fc028c46c293e1d57053454796
Autor:
Jing Huang, Jing Zhang, Marina A. Bellani, Durga Pokharel, Julia Gichimu, Ryan C. James, Himabindu Gali, Chen Ling, Zhijiang Yan, Dongyi Xu, Junjie Chen, Amom Ruhikanta Meetei, Lei Li, Weidong Wang, Michael M. Seidman
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1794-1808.e5 (2019)
Summary: Eukaryotic replisomes are driven by the mini chromosome maintenance (MCM [M]) helicase complex, an offset ring locked around the template for leading strand synthesis by CDC45 (C) and GINS (G) proteins. Although the CDC45 MCM GINS (CMG) stru
Externí odkaz:
https://doaj.org/article/aaee9a3577bd4fb7b845c27a87340523
Autor:
Young-Kwon Park, Zhijiang Yan, Weiqun Peng, Ji-Eun Lee, Weidong Wang, Kai Ge, Tommy O'Haren, Kaitlin McKernan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Cell type-specific enhancers are activated by coordinated actions of lineage-determining transcription factors (LDTFs) and chromatin regulators. The SWI/SNF chromatin remodeling complex BAF and the histone H3K4 methyltransferase MLL4 (KMT2D) are both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6e4762337377e6cc6fc101e0fffc88
https://doi.org/10.1101/2020.06.24.168146
https://doi.org/10.1101/2020.06.24.168146
Autor:
Elin Lehrmann, Weidong Wang, Zhong Wang, Jian Sima, Yongqing Zhang, Ramaiah Nagaraja, Zhijiang Yan, David Schlessinger, Yaohui Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Specific gene regulation in organ development remains poorly understood. Here, we report that skin-specific ectodysplasin A (Eda) signaling triggers the formation of a protein complex that includes a BAF complex, an NF-kB dimer of p50/Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1174c739d2c2ad1f489d5f07f1eaec85
https://doi.org/10.1073/pnas.1800930115
https://doi.org/10.1073/pnas.1800930115
Autor:
Tatsuo Fukagawa, Chen Ling, Zhijiang Yan, Ye Zhao, Wei Yang, Weidong Wang, David A. Fox, Duck Yeon Lee
Publikováno v:
Cell Research. 24:560-575
Histone-fold proteins typically assemble in multiprotein complexes to bind duplex DNA. However, one histone-fold complex, MHF, associates with Fanconi anemia (FA) protein FANCM to form a branched DNA remodeling complex that senses and repairs stalled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e23e95fd9efa17d47c46f04ed889c9
https://doi.org/10.1038/cr.2014.42
https://doi.org/10.1038/cr.2014.42
Autor:
Ryan C. James, Amom Ruhikanta Meetei, Michael M. Seidman, Zhijiang Yan, Jing Zhang, Durga Pokharel, Chen Ling, Himabindu Gali, Julia Gichimu, Marina A. Bellani, Junjie Chen, Lei Li, Weidong Wang, Dongyi Xu, Jing Huang
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1794-1808.e5 (2019)
Summary: Eukaryotic replisomes are driven by the mini chromosome maintenance (MCM [M]) helicase complex, an offset ring locked around the template for leading strand synthesis by CDC45 (C) and GINS (G) proteins. Although the CDC45 MCM GINS (CMG) stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872b47bc5bd1347109164f5d937f2610
https://doi.org/10.1016/j.celrep.2019.04.032
https://doi.org/10.1016/j.celrep.2019.04.032
Autor:
Lioudmila V. Sharova, Kazuhiro Aiba, Ryo Matoba, Alexei A. Sharov, Minoru S.H. Ko, Chen Ling, Zhijiang Yan, Weidong Wang, Zhong Wang, Yulan Piao
Publikováno v:
Stem Cells. 26:1155-1165
Whether SWI/SNF chromatin remodeling complexes play roles in embryonic stem (ES) cells remains unknown. Here we show that SWI/SNF complexes are present in mouse ES cells, and their composition is dynamically regulated upon induction of ES cell differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc54d2ad26840f6812c2d4a2d53e134f
https://doi.org/10.1634/stemcells.2007-0846
https://doi.org/10.1634/stemcells.2007-0846
Autor:
Zhijiang Yan, Detlev Schindler, Minoru Takata, Amom Ruhikanta Meetei, Maureen E. Hoatlin, Reinhard Kalb, Johan P. de Winter, Yutong Xue, Masamichi Ishiai, Kornelia Neveling, Weidong Wang, Annette L. Medhurst, Hans Joenje, Anneke B. Oostra, Abdullah Mahmood Ali, Chen Ling, Arleen D. Auerbach
Publikováno v:
The EMBO Journal. 26:2104-2114
The Fanconi anemia (FA) core complex plays a central role in the DNA damage response network involving breast cancer susceptibility gene products, BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a42cd6da19ba007bcab22c51c57cb2
https://doi.org/10.1038/sj.emboj.7601666
https://doi.org/10.1038/sj.emboj.7601666
Autor:
Yutong Xue, Stephen C. West, El Houari Laghmani, Alberto Ciccia, Chen Ling, Rachel Coulthard, Amom Ruhikanta Meetei, Neil Q. McDonald, Weidong Wang, Hans Joenje, Zhijiang Yan, Johan P. de Winter
Publikováno v:
Molecular Cell. 25:331-343
The Fanconi anemia (FA) core complex plays a crucial role in a DNA damage response network with BRCA1 and BRCA2. How this complex interacts with damaged DNA is unknown, as only the FA core protein FANCM (the homolog of an archaeal helicase/nuclease k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68ec4ff32d8ba7ce0c365e79cba20aa
https://doi.org/10.1016/j.molcel.2007.01.003
https://doi.org/10.1016/j.molcel.2007.01.003
Autor:
Jonathan H. Dennis, Xiaolin Gao, Ienglam Lei, Zhijiang Yan, Jason A. West, Leonid Gnatovskiy, Zhong Wang, Weidong Wang, Peng Fang, Robert E. Kingston
Publikováno v:
The Journal of biological chemistry. 290(31)
The unique chromatin signature of ES cells is fundamental to the pluripotency and differentiation of ES cells. One key feature is the poised chromatin state of master developmental genes that are transcriptionally repressed in ES cells but ready to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fee35db0f3070c56cee79a5af10aeef
https://pubmed.ncbi.nlm.nih.gov/26070559
https://pubmed.ncbi.nlm.nih.gov/26070559