Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zhijian James Chen"'
Autor:
Daria Beshnova, Yan Fang, Mingjian Du, Yehui Sun, Fenghe Du, Jianfeng Ye, Zhijian James Chen, Bo Li
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2212-2222 (2022)
Coronavirus disease 2019 (COVID-19) caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide as a severe pandemic and caused enormous global health and economical damage. Since December 2019, more than 197 m
Externí odkaz:
https://doaj.org/article/3de84621375e45db87efe2eaa98dbd43
cGAS is an evolutionarily conserved enzyme that plays a pivotal role in immune defense against microbial infection1-3. In vertebrate animals, cGAS is activated by DNA to produce cyclic GMP-AMP (cGAMP)4,5 , which initiates a signaling cascade leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0609adf73a4c57865f1d90e98332a7a5
https://doi.org/10.21203/rs.3.rs-1578554/v1
https://doi.org/10.21203/rs.3.rs-1578554/v1
Autor:
Zhijian James Chen
Publikováno v:
The FASEB Journal. 29
The inappropriate presence of DNA in the cytosol is a danger signal that alerts the host of potential microbial invasion and triggers innate immune responses including the production of type-I inte...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa6a7b00feae0b824c2a9cbe405f4e32
https://doi.org/10.1096/fasebj.29.1_supplement.217.1
https://doi.org/10.1096/fasebj.29.1_supplement.217.1
Publikováno v:
Zhonghua nei ke za zhi. 42(12)
To investigate the effect of peroxisome proliferator-activated receptor alpha and gamma (PPARalpha and PPARgamma) ligands on free fatty acid (FFA)-induced pancreatic beta-cell impairment.Insulinoma cell line beta-cell (INS-1 cells) were treated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e16bc2c5c94d9ac9e1ba058b4878349c
https://pubmed.ncbi.nlm.nih.gov/14728875
https://pubmed.ncbi.nlm.nih.gov/14728875
Autor:
Zhijian ’James’ Chen
Publikováno v:
Cytokine. 70:22
The inappropriate presence of DNA in the cytosol is a danger signal that alerts the host of potential microbial invasion and triggers innate immune responses including the production of type-I interferons. Under certain pathological conditions, self
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7761c98e0d2364bf1b89d900c595443
https://doi.org/10.1016/j.cyto.2014.07.228
https://doi.org/10.1016/j.cyto.2014.07.228