Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Zhihui Dou"'
Autor:
Zhihui Dou, Huiwen Lei, Wei Su, Taotao Zhang, Xiaohua Chen, Boyi Yu, Xiaogang Zhen, Jing Si, Chao Sun, Hong Zhang, Cuixia Di
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-11 (2024)
Abstract Dysregulation of anti-apoptotic and pro-apoptotic protein isoforms arising from aberrant splicing is a crucial hallmark of cancers and may contribute to therapeutic resistance. Thus, targeting RNA splicing to redirect isoform expression of a
Externí odkaz:
https://doaj.org/article/2c3e2ba8d5fa4cff88169be4eeba2a59
Autor:
Taotao Zhang, Huiwen Lei, Xiaohua Chen, Zhihui Dou, Boyi Yu, Wei Su, Wei Wang, Xiaodong Jin, Takanori Katsube, Bing Wang, Hong Zhang, Qiang Li, Cuixia Di
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Radiopharmaceuticals play a vital role in cancer therapy. The carrier of radiopharmaceuticals can precisely locate and guide radionuclides to the target, where radionuclides kill surrounding tumor cells. Effective application of radiopharmac
Externí odkaz:
https://doaj.org/article/989b359e68ba4d6c8d37f8d8d5c4a2ed
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background To assess the prevalence of anemia before and after antiretroviral therapy (ART) initiation and to identify impact of anemia on mortality among HIV-infected patients in China during the Treat-All era. Methods All HIV-infected pati
Externí odkaz:
https://doaj.org/article/0b13cada07f547549e5cc492a7602788
Autor:
Xiaohua Chen, Taotao Zhang, Wei Su, Zhihui Dou, Dapeng Zhao, Xiaodong Jin, Huiwen Lei, Jing Wang, Xiaodong Xie, Bo Cheng, Qiang Li, Hong Zhang, Cuixia Di
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract TP53, a crucial tumor suppressor gene, is the most commonly mutated gene in human cancers. Aside from losing its tumor suppressor function, mutant p53 (mutp53) often acquires inherent, novel oncogenic functions, which is termed “gain-of-fu
Externí odkaz:
https://doaj.org/article/de3ebfc8fd634078865f3b7040816cf0
Autor:
Caipeng Xu, Xiaohua Chen, Xuetian Zhang, Dapeng Zhao, Zhihui Dou, Xiaodong Xie, Hongyan Li, Hongying Yang, Qiang Li, Hong Zhang, Cuixia Di
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract RNA-binding motif protein 39 (RBM39), as a key factor in tumor-targeted mRNA and protein expression, not only plays a vital role in tumorigenesis, but also has broad development prospects in clinical treatment and drug research. Moreover, si
Externí odkaz:
https://doaj.org/article/9a2d8c8e65d8484fa61f1832ef8524d5
Autor:
Zhihui Dou, Dapeng Zhao, Xiaohua Chen, Caipeng Xu, Xiaodong Jin, Xuetian Zhang, Yupei Wang, Xiaodong Xie, Qiang Li, Cuixia Di, Hong Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Bcl-x pre-mRNA splicing serves as a typical example to study the impact of alternative splicing in the modulation of cell death. Dysregulation of Bcl-x apoptotic isoforms caused by precarious equilibrium splicing is implicated in genesis and
Externí odkaz:
https://doaj.org/article/629741d9d1d149f3a181de99dbe77287
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Tuberculosis (TB) is an infectious disease that threatens human safety. Mainland China is an area with a high incidence of tuberculosis, and the task of tuberculosis prevention and treatment is arduous. This paper aims to study the impact of
Externí odkaz:
https://doaj.org/article/fbdbdb44393f43bba8392dfad681fec9
Autor:
Xingting Bao, Jinhua Zhang, Guomin Huang, Junfang Yan, Caipeng Xu, Zhihui Dou, Chao Sun, Hong Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-13 (2021)
Abstract Mitochondria are essential cellular organelles that are involved in regulating cellular energy, metabolism, survival, and proliferation. To some extent, cancer is a genetic and metabolic disease that is closely associated with mitochondrial
Externí odkaz:
https://doaj.org/article/5c7f0ff96eec4255a2c9443b754a4975
Autor:
Xingting Bao, Xiongxiong Liu, Qingfeng Wu, Fei Ye, Zheng Shi, Dan Xu, Jinhua Zhang, Zhihui Dou, Guomin Huang, Hong Zhang, Chao Sun
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 453 (2023)
Radiotherapy (RT) is one of the most effective cancer treatments. However, successful radiation protection for normal tissue is a clinical challenge. Our previous study observed that MitoQ, a mitochondria-targeted antioxidant, was adsorbed to the inn
Externí odkaz:
https://doaj.org/article/5321b4eeca9e4edfa4f986e309e3c313
Autor:
Jiaye Liu, Lifeng Wang, Yuying Hou, Yan Zhao, Zhihui Dou, Ye Ma, Dawei Zhang, Yasong Wu, Decai Zhao, Zhongfu Liu, Fujie Zhang, Lei Jin, Ji-Yuan Zhang, Ruonan Xu, Ming Shi, Lei Huang, Zunyou Wu, Mengjie Han, George F. Gao, Fu-Sheng Wang
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2550-2561 (2020)
ABSTRACTUsing normalization of CD4 counts as the main evaluation parameter of complete immune restoration for HIV-1 patients under antiretroviral therapy (ART) might be not enough. A comprehensive evaluation system more accurately reflecting immune r
Externí odkaz:
https://doaj.org/article/d9b6222a0ad44cf880e43292ebe74e82