Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zhihua Julia Qiu"'
Autor:
Patricia Siguenza, An Song, Suzanne Brignoli, Valerie Quarmby, Saloumeh K Fischer, Yong Ying, Sock-Cheng Lewin-Koh, Robert Hendricks, Zhihua Julia Qiu, Daniel Coleman
Publikováno v:
Bioanalysis. 7:1775-1783
Zhihua Julia Qiu has over 20 years post PhD experience in academic institutes, pharmaceutical industry and biotechnology startup settings; focused on novel therapeutics discovery and development and diagnostic tools. She is currently a Scientist in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c7a1bf37be5d45eb8e0bb372bebddd
https://doi.org/10.4155/bio.15.91
https://doi.org/10.4155/bio.15.91
Autor:
Ben Tran, Zhihua Julia Qiu, Taylor Zhang, Daniel P. Hewitt, Hélène Gazzano-Santoro, Max L. Tejada, Yung-Hsiang Kao, Xiaoying Gao, Jennifer Zhang
Publikováno v:
Analytical Chemistry. 84:7112-7123
The heterogeneity in therapeutic antibodies arising from buried unpaired cysteines has not been well studied. This paper describes the characterization of two unpaired cysteines in a recombinant humanized IgG1 monoclonal antibody (referred to as mAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed463ef0da98f7f807a44b720f44460
https://doi.org/10.1021/ac301426h
https://doi.org/10.1021/ac301426h
Publikováno v:
Pharmaceutical Research. 29:3180-3187
To characterize the pharmacokinetic (PK) and pharmacodynamic (PD) properties of a monoclonal antibody directed against the B-cell activating factor (BAFF) receptor 3 (BR3), following intravenous (IV) and subcutaneous (SC) administration in mice.Singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4051335d8c11f812be0bfe0e0a226d2b
https://doi.org/10.1007/s11095-012-0813-6
https://doi.org/10.1007/s11095-012-0813-6
Autor:
Jeremy Good, Yong Ying, Amena Rahman, Daniel Coleman, Jihong Yang, Jenny Jiang, Michael Fox, Valerie Quarmby, Zhihua Julia Qiu, John B. Lowe, Sock-Cheng Lewin-Koh, An Song, Kun Peng
Publikováno v:
Journal of Immunological Methods. 362:101-111
Electrochemiluminescence (ECL) assays have been widely used for the detection of anti-therapeutic antibodies (ATAs) against biotherapeutics. With the discontinuation of BioVeris (BV) ECL platform, an alternative technology was needed to replace BV as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfb0adad56f7e07732fe0b3fed21793
https://doi.org/10.1016/j.jim.2010.09.013
https://doi.org/10.1016/j.jim.2010.09.013
Autor:
Jeff Lutman, Allen Nguyen, Chae Janeka Reed, Zhihua Julia Qiu, Anan Chuntharapai, Judy Young, Jane L. Grogan, Xiaoying Gao, Laura DeForge, Rong Deng, Yong Ying, Wai Lee Wong
Publikováno v:
Journal of immunological methods. 424
During drug development, measurement of suitable pharmacodynamic biomarkers is key to establishing in vivo drug activity. Binding of monoclonal antibody (mAb) therapeutics to soluble target proteins often results in elevated serum levels of their tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4755c546a7b68670664751b3e5d269c1
https://pubmed.ncbi.nlm.nih.gov/26009247
https://pubmed.ncbi.nlm.nih.gov/26009247
Autor:
Joo-Hee Yi, Douglas D. Leipold, Corinna Lei, Bei Wang, Zhihua Julia Qiu, Surinder Kaur, Connie Mahood, Yanhong Li, Randall C. Dere, Kirsten Achilles Poon, Montserrat Carrasco-Triguero
Publikováno v:
Bioanalysis. 5(9)
Background: Antibody–drug conjugates (ADCs) such as Kadcyla™ (ado-trastuzumab emtansine [T-DM1]) present covalently bound cytotoxic drugs, which may influence their immunogenicity potential compared with antibody therapies. Therefore, ADCs requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63022442fd166dade191d2a9e4c546b
https://pubmed.ncbi.nlm.nih.gov/23641693
https://pubmed.ncbi.nlm.nih.gov/23641693
Autor:
Judy Young, Allen Nguyen, Zhihua Julia Qiu, Yong Ying, Xiaoying Gao, Chae Reed, Anan Chuntharapai, Rong Deng, Jeff Luttman, Jane Grogan, Wai Lee Wong, Laura DeForge
Publikováno v:
The Journal of Immunology. 188:62.5-62.5
Lymphotoxin α (LTα) is a TNF superfamily cytokine secreted from activated lymphocytes as a homotrimer (LTα3) or complexed on the cell-surface with LTβ as heterotrimers. Compelling evidence indicates that LTα is involved in the pathophysiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73da1f579e64e4cec77806d902db0417
https://doi.org/10.4049/jimmunol.188.supp.62.5
https://doi.org/10.4049/jimmunol.188.supp.62.5
Autor:
Triguero, Montserrat Carrasco, Joo-Hee Yi, Dere, Randall, Zhihua Julia Qiu, Lei, Corinna, Yanhong Li, Mahood, Connie, Bei Wang, Leipold, Douglas, Poon, Kirsten Achilles, Kaur, Surinder
Publikováno v:
Bioanalysis; May2013, Vol. 5 Issue 9, p1007-1023, 17p