Zobrazeno 1 - 10
of 2 181
pro vyhledávání: '"Zhihong, LI"'
Autor:
Haitao Tu, Xin Yi Yeo, Zhi-Wei Zhang, Wei Zhou, Jayne Yi Tan, Li Chi, Sook-Yoong Chia, Zhihong Li, Aik Yong Sim, Brijesh Kumar Singh, Dongrui Ma, Zhidong Zhou, Isabelle Bonne, Shuo-Chien Ling, Adeline S.L. Ng, Sangyong Jung, Eng-King Tan, Li Zeng
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background The expansion of GGC repeats (typically exceeding 60 repeats) in the 5’ untranslated region (UTR) of the NOTCH2NLC gene (N2C) is linked to N2C-related repeat expansion disorders (NREDs), such as neuronal intranuclear inclusion d
Externí odkaz:
https://doaj.org/article/53616a0e246543b1ac81004a61f53ceb
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-37 (2024)
Abstract RNA splicing is a fundamental step of gene expression. While constitutive splicing removes introns and joins exons unbiasedly, alternative splicing (AS) selectively determines the assembly of exons and introns to generate RNA variants corres
Externí odkaz:
https://doaj.org/article/15ce628846914a96974c80d15632a932
Autor:
Ranran Li, Chunduo Wang, Kexin Xu, Zongzhu Zhan, Siyi He, Jihua Ren, Fan Li, Nana Tao, Zhihong Li, Zhen Yang, Haibo Yu
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Hepatitis B virus (HBV) infection is a persistent global public health problem, and curing for chronic hepatitis B (CHB) through the application of existing antiviral drugs is beset by numerous challenges. The viral protein HBx is
Externí odkaz:
https://doaj.org/article/810203c5acff4bbd9657eacc6d5c15e7
Autor:
Haodong Xu, Ruifeng Hu, Xianjun Dong, Lan Kuang, Wenchao Zhang, Chao Tu, Zhihong Li, Zhongming Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Advances in mass spectrometry accelerates the characterization of HLA ligandome, necessitating the development of efficient methods for immunopeptidomics analysis and (neo)antigen prediction. We develop ImmuneApp, an interpretable deep learn
Externí odkaz:
https://doaj.org/article/a38a1b6bdcee40039fb5a962ba450fe7
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Cancer-associated fibroblasts (CAFs) are a diverse stromal cell population within the tumour microenvironment, where they play fundamental roles in cancer progression and patient prognosis. Multiple lines of evidence have identified that CAF
Externí odkaz:
https://doaj.org/article/d38a1473783640858b96822645571ab7
Autor:
Haijuan Wu, Zhihong Li
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 5, Pp 1197-1208 (2024)
An innovative dual-thickness semi-transparent beamstop designed to enhance the performance of small-angle X-ray scattering (SAXS) experiments is introduced. This design integrates two absorbers of differing thicknesses side by side into a single atte
Externí odkaz:
https://doaj.org/article/0810aeb833f144ddbea8e1070f594ec4
Publikováno v:
Jin'gangshi yu moliao moju gongcheng, Vol 44, Iss 4, Pp 428-432 (2024)
Objectives: It is important to analyze the status of each industry, which provides not only a direct vision but also a vital reference to all. Methods: The operation of China's superhard industry in 2023 was analyzed based on an in-depth investigatio
Externí odkaz:
https://doaj.org/article/5ba6830aa4c742e3ac2f0ece8b07c316
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Among over 2,000 species of mealybugs (Hemiptera: Pseudococcidae), only 13 genomes have been published so far, seriously limiting the researches on the phylogeny and adaptive evolution of this group. The continuous publication of mealybug ge
Externí odkaz:
https://doaj.org/article/ab434e1b2aed413aae5bbda6d40c108d
Autor:
Cuiyu Tan, Shuqiang Huang, Liying Xu, Tongtong Zhang, Xiaojun Yuan, Zhihong Li, Miaoqi Chen, Cairong Chen, Qiuxia Yan
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Changes in the oxidative stress and lipid metabolism (OSLM) pathways play important roles in polycystic ovarian syndrome (PCOS) pathogenesis and development. Consequently, a systematic analysis of genes related to OSLM was conduct
Externí odkaz:
https://doaj.org/article/8a872c993a4843ceb9c03d72756583f3
Autor:
Hui Zhang, Xiameng Su, Leirong Gu, Ming Tan, Yuting Liu, Kexin Xu, Jihua Ren, Juan Chen, Zhihong Li, Shengtao Cheng
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The HBV core protein (HBc) is an important viral protein of HBV that plays an indispensable role in the lifecycle of HBV, including capsid assembly and transport, reverse transcription and virus release. In recent years, evidence has shown t
Externí odkaz:
https://doaj.org/article/5f66381844de455db709ecc10c0c29f3