Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zhihao Shu"'
Autor:
Ruoru Wu, Zhihao Shu, Fei Zou, Shaoli Zhao, Saolai Chan, Yaxian Hu, Hong Xiang, Shuhua Chen, Li Fu, Dongsheng Cao, Hongwei Lu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract In view of the alarming increase in the burden of diabetes mellitus (DM) today, a rising number of patients with diabetic kidney disease (DKD) is forecasted. Current DKD predictive models often lack reliable biomarkers and perform poorly. In
Externí odkaz:
https://doaj.org/article/ce24fe4b260a4026a6306567d642eee7
Autor:
Zhihao Shu, Shuhua Chen, Hong Xiang, Ruoru Wu, Xuewen Wang, Jie Ouyang, Jing Zhang, Huiqin Liu, Alex F. Chen, Hongwei Lu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Diabetes is a chronic metabolic disorder that can cause many microvascular and macrovascular complications, including diabetic nephropathy. Endothelial cells exhibit phenotypic and metabolic diversity and are affected by metabolic disorders. Whether
Externí odkaz:
https://doaj.org/article/d6e5bb6069414140b4429a6094b06b46
Autor:
Yao Lu, Junru Wu, Wenduo Gu, Zhijun Huang, Zhihao Shu, Miao Huang, Jingyuan Chen, Mengli Zhou, Yuanyuan Bai, Xiang Chen, Yi Xiao, Minxue Shen, Dan Luo, Qihong Deng, Liyuan Chai, Meian He, Jicheng Gong, Hong Yuan, Qingbo Xu, Jingjing Cai
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 211, Iss , Pp 111881- (2021)
Background: Cadmium is the most prevalent form of heavy metal contaminant globally and its exposure rises serious health concern. Chronic exposure to cadmium causes immune disturbances. However, few studies have addressed how it affects circulating i
Externí odkaz:
https://doaj.org/article/fb1c78277bdb4cd58a3f955e5d3c90b9
Autor:
Zhihao Shu, Rongrong Xie, Li-Xin Gao, Sun Dandan, Tan Qian, Junyou Li, Yazhou Li, Mengqi Liu, Jia Li, Hong Liu, Shimeng Guo, Yi Zang, Ru Hongbo, Yu Zhou
Publikováno v:
Journal of Medicinal Chemistry. 63:12748-12772
Farnesoid X receptor (FXR) plays a key role in bile acid homeostasis, inflammation, fibrosis, and metabolism of lipid and glucose and becomes a promising therapeutic target for nonalcoholic steatohepatitis (NASH) or other FXR-dependent diseases. The
Publikováno v:
Journal of Cellular and Molecular Medicine. 24:10290-10301
There are many different types of cardiovascular diseases, which impose a huge economic burden due to their extremely high mortality rates, so it is necessary to explore the underlying mechanisms to achieve better supportive and curative care outcome
Autor:
Wenfang Xiong, Jie Ouyang, Zhihao Shu, Jie Xiao, Xuewen Wang, Hong Xiang, Hongwei Lu, Shuhua Chen, Hengdao Liu, Ruoru Wu, Alex F. Chen, Shaoli Zhao, Huiqin Liu, Yulan Liu, Jing Zhang
Background: The prevalence of diabetic vascular complications is rapidly increasing, especially in the diabetes mellitus with hyperlipidemia. Consistent hyperglycemia and hyperlipidemia impairs microvascular, but lack of effective intervention target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::028648f290b5e51baf2e1d4598cc0946
https://doi.org/10.21203/rs.3.rs-795542/v1
https://doi.org/10.21203/rs.3.rs-795542/v1
Autor:
Xuewen, Wang, Shuhua, Chen, Hong, Xiang, Xiaoyan, Wang, Jie, Xiao, Shaoli, Zhao, Zhihao, Shu, Jie, Ouyang, Ziwei, Liang, Minzi, Deng, Xuejie, Chen, Jing, Zhang, Huiqin, Liu, Qisheng, Quan, Peng, Gao, Jianing, Fan, Alex F, Chen, Hongwei, Lu
Publikováno v:
Biochemical Pharmacology. 201:115077
Vascular and immune dysfunctions are thought to be related to the pathogenesis of inflammatory bowel disease (IBD), but behind this, the exact mechanism of mucosal vascular endothelial barrier dysfunction and macrophage phenotypic transition is not f
Autor:
Chengcheng, Zhang, Danrong, Jing, Xiaoyan, Huang, Yi, Xiao, Zhihao, Shu, Dan, Luo, Yanying, Duan, Meian, He, Shuiyuan, Xiao, Xiang, Chen, Zhijun, Huang, Minxue, Shen
Publikováno v:
Science of The Total Environment. 826:154062
Exposure to single metals have been linked to childhood behavior problems, But little is known about the effects of metals mixtures on children. We aimed to evaluate associations of multiple metals exposures in urine with childhood behavior in China.
Autor:
Yulan Liu, Hong Xiang, Wenfang Xiong, Jie Ouyang, Hengdao Liu, Shaoli Zhao, Jie Xiao, Jialing Li, Zhihao Shu, Xuewen Wang, Huiqin Liu, Jing Zhang, Jianing Fan, Ying Li, Shuhua Chen, Hongwei Lu
Publikováno v:
Diabetes and Vascular Disease Research. 19:147916412211025
Objectives This study aims to determine the role and mechanism of autophagy in endothelial cell dysfunction by glucolipotoxicity. Methods Human umbilical vein endothelial cells (HUVECs) were treated with high glucose and high palmitic acid. The numbe
Autor:
Chengcheng Zhang, Xiaoyan Huang, Yi Xiao, Zhihao Shu, Dan Luo, Yanying Duan, Meian He, Shui-yuan Xiao, Xiang Chen, Zhijun Huang, Minxue Shen
Publikováno v:
SSRN Electronic Journal.