Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Zhihan Zhao"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Ferroptosis is a special form of regulated cell death, which is reported to play an important role in a variety of traumatic diseases by promoting lipid peroxidation and devastating cell membrane structure. Pelvic floor dysfunction (PFD) is
Externí odkaz:
https://doaj.org/article/d0c59fadac604c6d9d29f2ba0cae4e82
Autor:
Zhen Xie, Hao Hui, Zhihan Zhao, Wenjin Yu, Rui Wu, Yanzhao Zhu, Yuan Song, Bingqing Cao, Wenzhen Shi, Di Zhao, Yunsong Zhao, Junchao Lv, Qian Yao, Yan Duan, Jingwen Li, Haijun Zhang, Linfu Zhou, Xiaotian Wang, Ye Tian, Gang Zhao
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 63-74 (2022)
In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed th
Externí odkaz:
https://doaj.org/article/7ffdf69931524d068e9508fdb399c61b
Publikováno v:
Animal Cells and Systems, Vol 26, Iss 4, Pp 192-202 (2022)
Excessive mechanical traction damages the levator ani muscle (LAM), increasing the incidence of pelvic floor dysfunction (PFD). In this study, we explored the effects of oxidized nicotinamide adenine dinucleotide (NAD+) on the damage to both muscle c
Externí odkaz:
https://doaj.org/article/a743611fcfd74e24b7964cf97cc4ebc5
Autor:
Katherine Sattler, Ibrahim El-Battrawy, Lukas Cyganek, Siegfried Lang, Huan Lan, Xin Li, Zhihan Zhao, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiaobo Zhou, Ibrahim Akin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The non-selective cation channel transient receptor potential vanilloid 1 (TRPV1) is expressed throughout the cardiovascular system. Recent evidence shows a role for TRPV1 in inflammatory processes. The role of TRPV1 for myocardial inflammat
Externí odkaz:
https://doaj.org/article/a7f9a71d55e74244b426387ab24d1474
Autor:
Mao Chen, Suting Li, Menglei Hao, Jue Chen, Zhihan Zhao, Shasha Hong, Jie Min, Jianming Tang, Ming Hu, Li Hong
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2122-2136 (2020)
Loss of T‐type calcium channel (TCC) function has been reported to result in decreased cell viability and impaired muscle regeneration, but the underlying mechanisms remain largely unknown. We previously found that expression of TCC is reduced in a
Externí odkaz:
https://doaj.org/article/74b45ca0da6b45b2838ba09b42327578
Publikováno v:
Case Reports in Gastroenterology, Vol 14, Iss 1, Pp 39-47 (2020)
Gilbert syndrome (GS) is characterized by intermittent indirect bilirubin elevation. Several antiepileptic drugs (AEDs) impair the liver function to different degrees, such as valproic acid, lamotrigine, phenobarbital, phenytoin, and carbamazepine. H
Externí odkaz:
https://doaj.org/article/229ef00c8f4c4b52b95fb1f2b6a4ea59
Autor:
Rujia Zhong, Theresa Schimanski, Feng Zhang, Huan Lan, Alyssa Hohn, Qiang Xu, Mengying Huang, Zhenxing Liao, Lin Qiao, Zhen Yang, Yingrui Li, Zhihan Zhao, Xin Li, Lena Rose, Sebastian Albers, Lasse Maywald, Jonas Müller, Hendrik Dinkel, Ardan Saguner, Johannes W. G. Janssen, Narasimha Swamy, Yannick Xi, Siegfried Lang, Mandy Kleinsorge, Firat Duru, Xiaobo Zhou, Sebastian Diecke, Lukas Cyganek, Ibrahim Akin, Ibrahim El-Battrawy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8313 (2022)
Aims: Some gene variants in the sodium channels, as well as calcium channels, have been associated with Brugada syndrome (BrS). However, the investigation of the human cellular phenotype and the use of drugs for BrS in presence of variant in the calc
Externí odkaz:
https://doaj.org/article/0fc5cabdcf3c4f0d9c2e49983942d643
Autor:
Mengying Huang, Zhenxing Liao, Xin Li, Zhen Yang, Xuehui Fan, Yingrui Li, Zhihan Zhao, Siegfried Lang, Lukas Cyganek, Xiaobo Zhou, Ibrahim Akin, Martin Borggrefe, Ibrahim El-Battrawy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Aims: The short QT syndrome type 1 (SQT1) is linked to hERG channel mutations (e.g., N588K). Drug effects on hERG channel gating kinetics in SQT1-cells have not been investigated.Methods: This study used hiPSC-CMs of a healthy donor and a SQT1-patien
Externí odkaz:
https://doaj.org/article/2f5fe5842def4a55bdbdf25d5c1e9677
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Objectives: The purpose of this study was to verify the veracity and reliability of the INCNS score for prediction of neurological ICU (NICU) mortality and 3-month functional outcome and mortality in comatose patients.Methods: In this prospective stu
Externí odkaz:
https://doaj.org/article/0f1010dcb706444b8fe3cd0cc59f74bc
Autor:
Ibrahim El-Battrawy, Jonas Müller, Zhihan Zhao, Lukas Cyganek, Rujia Zhong, Feng Zhang, Mandy Kleinsorge, Huan Lan, Xin Li, Qiang Xu, Mengying Huang, Zhenxing Liao, Alexander Moscu-Gregor, Sebastian Albers, Hendrik Dinkel, Siegfried Lang, Sebastian Diecke, Wolfram-Hubertus Zimmermann, Jochen Utikal, Thomas Wieland, Martin Borggrefe, Xiaobo Zhou, Ibrahim Akin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
BackgroundAmong rare channelopathies BrS patients are at high risk of sudden cardiac death (SCD). SCN5A mutations are found in a quarter of patients. Other rare gene mutations including SCN1B have been implicated to BrS. Studying the human cellular p
Externí odkaz:
https://doaj.org/article/e4d847f1203f41bca3784f5844070f87