Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Zhiguang Huo"'
Autor:
Mark R. Viggars, Hannah E. Berko, Stuart J. Hesketh, Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Ryan A. Martin, Isabel G. Jennings, Zhiguang Huo, Karyn A. Esser
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101980- (2024)
Objective: In this investigation, we addressed the contribution of the core circadian clock factor, BMAL1, in skeletal muscle to both acute transcriptional responses to exercise and transcriptional remodeling in response to exercise training. Additio
Externí odkaz:
https://doaj.org/article/4f8165619b1142dbbf2096c2b599ae2d
Autor:
Xiaoxiao Wen, Helena Palma-Gudiel, Guanhong Miao, Mingjing Chen, Zhiguang Huo, Hao Peng, Stephen Anton, Gang Hu, Ricky Brock, Phillip J. Brantley, Jinying Zhao
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Alterations in DNA methylation (DNAm) have been reported to be a mechanism by which bariatric surgeries resulted in considerable metabolic improvements. Previous studies have mostly focused on change in DNAm following weight-loss
Externí odkaz:
https://doaj.org/article/dfaf8b432be54484b1e402f7ee695919
Autor:
Iqbal Mahmud, Guimei Tian, Jia Wang, Tarun E. Hutchinson, Brandon J. Kim, Nikee Awasthee, Seth Hale, Chengcheng Meng, Allison Moore, Liming Zhao, Jessica E. Lewis, Aaron Waddell, Shangtao Wu, Julia M. Steger, McKenzie L. Lydon, Aaron Chait, Lisa Y. Zhao, Haocheng Ding, Jian-Liang Li, Hamsa Thayele Purayil, Zhiguang Huo, Yehia Daaka, Timothy J. Garrett, Daiqing Liao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Cancer cells exhibit elevated lipid synthesis. In breast and other cancer types, genes involved in lipid production are highly upregulated, but the mechanisms that control their expression remain poorly understood. Using integrated transcrip
Externí odkaz:
https://doaj.org/article/7bed513e4be84384b1eeaf5eada78cd4
Autor:
Mingjing Chen, Guanhong Miao, Zhiguang Huo, Hao Peng, Xiaoxiao Wen, Stephen Anton, Dachuan Zhang, Gang Hu, Ricky Brock, Phillip J. Brantley, Jinying Zhao
Publikováno v:
Metabolites, Vol 14, Iss 2, p 116 (2024)
It is well recognized that patients with severe obesity exhibit remarkable heterogeneity in response to different types of weight-loss interventions. Those who undergo Roux-en-Y gastric bypass (RYGB) usually exhibit more favorable glycemic outcomes t
Externí odkaz:
https://doaj.org/article/1e5aab0aab8349d180ac7f98768a2cf3
Autor:
Chengguo Xing, John Malaty, Melissa Bou Malham, Anna Maria Abi Nehme, Breanne Freeman, Zhiguang Huo, Roberto Firpi-Morrel, Ramzi G. Salloum
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Tobacco use is the leading cause of many preventable diseases, resulting in premature death or disease. Given that the majority of adult who smoke want to stop, this health burden could be significantly reduced if the success rate
Externí odkaz:
https://doaj.org/article/45978af9b1e14db8a4ea567abd888510
Autor:
Jessica A. Peterson, Larissa J. Strath, Chavier Laffitte Nodarse, Asha Rani, Zhiguang Huo, Lingsong Meng, Sean Yoder, James H. Cole, Thomas C. Foster, Roger B. Fillingim, Yenisel Cruz-Almeida
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2178-2187 (2022)
Chronic musculoskeletal pain is a health burden that may accelerate the aging process. Accelerated brain aging and epigenetic aging have separately been observed in those with chronic pain. However, it is unknown whether these biological markers of a
Externí odkaz:
https://doaj.org/article/aae0aa138060444e9da2fe3e33601a46
Autor:
Soamy Montesino-Goicolea, Olga Nin, Barbara M. Gonzalez, Nathalie J. Sawczuk, Chavier Laffitte Nodarse, Pedro Antonio Valdes-Hernandez, Elijah Jackson, Zhiguang Huo, Jessie Elise T. Somerville, Eric C. Porges, Cameron Smith, Roger B. Fillingim, Yenisel Cruz-Almeida
Publikováno v:
Contemporary Clinical Trials Communications, Vol 32, Iss , Pp 101066- (2023)
Approximately 1.71 billion people globally live with musculoskeletal pain conditions, including low back pain, knee pain, and neck pain Cieza et al. (2020). In the US, an estimated 20.4% of U.S. adult had chronic pain and 8.0% of U.S. adults had high
Externí odkaz:
https://doaj.org/article/bd88764ae4284e5abcddea929a3c9e81
Autor:
Jessica A. Peterson, Joshua A. Crow, Alisa J. Johnson, Lingsong Meng, Asha Rani, Zhiguang Huo, Thomas C. Foster, Roger B. Fillingim, Yenisel Cruz-Almeida
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionChronic pain is one of the leading causes of disability that may accelerate biological aging and reduce physical function. Epigenetic clocks provide an estimate of how the system ages and can predict health outcomes such as physical funct
Externí odkaz:
https://doaj.org/article/d3818217c6ef44e7834a626ca2d40dc7
Autor:
Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Lingsong Meng, Xiping Zhang, Lauren G. Douma, Hannah M. Costello, Collin M. Douglas, Elnaz Ebrahimi, Ann Pham, Aline C. Oliveira, Chunhua Fu, Amy Nguyen, Bryan R. Alava, Stuart J. Hesketh, Andrew R. Morris, Mehari M. Endale, G. Ryan Crislip, Kit-yan Cheng, Elizabeth A. Schroder, Brian P. Delisle, Andrew J. Bryant, Michelle L. Gumz, Zhiguang Huo, Andrew C. Liu, Karyn A. Esser
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111982- (2023)
Summary: Cellular circadian clocks direct a daily transcriptional program that supports homeostasis and resilience. Emerging evidence has demonstrated age-associated changes in circadian functions. To define age-dependent changes at the systems level
Externí odkaz:
https://doaj.org/article/2f18b4dcc2854c8b81ce1f23e09506dc
Autor:
Soamy Montesino-Goicolea, Lingsong Meng, Asha Rani, Zhiguang Huo, Thomas C. Foster, Roger B. Fillingim, Yenisel Cruz-Almeida
Publikováno v:
Neurobiology of Pain, Vol 12, Iss , Pp 100107- (2022)
Our study aimed to identify differentially methylated regions (i.e., genomic region where multiple adjacent CpG sites show differential methylation) and their enriched genomic pathways associated with knee osteoarthritis pain (KOA). We recruited cogn
Externí odkaz:
https://doaj.org/article/38703b23431746f489939e172fec646e