Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Zhiguang, Su"'
Autor:
Daxin Cui, Xingrong Feng, Siman Lei, Hongmei Zhang, Wanxin Hu, Shanshan Yang, Xiaoqian Yu, Zhiguang Su, Jing Ni
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 7, Pp 791-805 (2024)
Abstract. Pancreatic β-cell failure due to a reduction in function and mass has been defined as a primary contributor to the progression of type 2 diabetes (T2D). Reserving insulin-producing β-cells and hence restoring insulin production are gainin
Externí odkaz:
https://doaj.org/article/25256b2c454142e6b5797c4264cd8f10
Publikováno v:
MedComm – Future Medicine, Vol 3, Iss 1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/da94bdb8570f4280bf2f4f0cdf59fc21
Autor:
Siyuan He, Xiaoqian Yu, Daxin Cui, Yin Liu, Shanshan Yang, Hongmei Zhang, Wanxin Hu, Zhiguang Su, Jing Ni
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 8, Pp 922-932 (2023)
Abstract. Background:. Pancreatic β-cells elevate insulin production and secretion through a compensatory mechanism to override insulin resistance under metabolic stress conditions. Deficits in β-cell compensatory capacity result in hyperglycemia a
Externí odkaz:
https://doaj.org/article/7b47ae6422f94c70b5766a6c43cbca1b
Autor:
Xueping Zhang, Dan Deng, Daxin Cui, Yin Liu, Siyuan He, Hongmei Zhang, Yaorui Xie, Xiaoqian Yu, Shanshan Yang, Yulong Chen, Zhiguang Su
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rational: Cholesterol sulfate (CS) is the most abundant known sterol sulfate in human plasma, and it plays a significant role in the control of metabolism and inflammatory response, which contribute to the pathogenesis of insulin resistance, β-cell
Externí odkaz:
https://doaj.org/article/9ebb31f8c4074419b3fdec1568c5643a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The endoplasmic reticulum (ER) and mitochondria are essential intracellular organelles that actively communicate via temporally and spatially formed contacts called mitochondria-associated membranes (MAMs). These mitochondria-ER contacts are not only
Externí odkaz:
https://doaj.org/article/9281cc9d7f774e5caca230d889a806ba
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Hepatic gluconeogenesis, de novo glucose synthesis from available precursors, plays a crucial role in maintaining glucose homeostasis to meet energy demands during prolonged starvation in animals. The abnormally increased rate of hepatic gluconeogene
Externí odkaz:
https://doaj.org/article/e321df7659c445fa9b42d2f8d13c500c
Autor:
Ying Wang, Shanshan Yang, Qiuyue Guan, Jinglu Chen, Xueping Zhang, Yuwei Zhang, Yiming Yuan, Zhiguang Su
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Nuclear factor-Y (NF-Y) consists of three evolutionary conserved subunits including NF-YA, NF-YB, and NF-YC; it is a critical transcriptional regulator of lipid and glucose metabolism and adipokine biosynthesis that are associated with type 2 diabete
Externí odkaz:
https://doaj.org/article/2ef22d02f27d4635afd60e240a322e1c
Autor:
Ning, Li, Nan, Wang, Wei, He, Yunyu, Feng, Qiang, Qiu, Huandi, Qiu, Li, Zheng, Yuexia, Yin, Bochuan, Wang, Yuanyuan, Sun, Cong, Pan, Klarke M, Sample, Juan, Huang, Zhiguang, Su, Zhihui, Li, Haojian, Zhang, Yiguo, Hu
Publikováno v:
International Journal of Biological Sciences. 18:2277-2291
RORA plays an important role in regulating circadian rhythms, inflammation, metabolism and cellular development. Herein, we explore the roles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08fad5cab9789b10543b8c145dd0f4e
https://doi.org/10.7150/ijbs.68939
https://doi.org/10.7150/ijbs.68939
Publikováno v:
Gene. 849
Transcriptional regulator PRD1-BF-1-RIZ1 homology (PR) domain containing protein-16 (PRDM16) has a fundamental function in maintaining energy homeostasis and regulating glucose and lipid metabolism, which are responsible for the development of type 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ee296436403ec88d738ea208d7ddd3
https://pubmed.ncbi.nlm.nih.gov/36174906
https://pubmed.ncbi.nlm.nih.gov/36174906
Autor:
Yulong Chen, Xiaoqian Yu, Ruixue Zhou, Dan Deng, Zhiguang Su, Yin Liu, Caixia Zhang, Xueping Zhang, Shanshan Yang, Siyuan He
Publikováno v:
Diabetes. 70:1703-1716
Pancreatic β-cell mass and insulin secretion are determined by the dynamic change of transcription factor expression levels in response to altered metabolic demand. Nuclear factor-Y (NF-Y) is an evolutionarily conserved transcription factor playing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38835f3dfb89bb113773a1972d09ef92
https://doi.org/10.2337/db20-1238
https://doi.org/10.2337/db20-1238