Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zhifen Cui"'
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
Severe respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses depend on host factors for the process of viral infection and replication. A better understanding of the dynamic interplay between viral pathogens and host cells, as well
Externí odkaz:
https://doaj.org/article/bca0d61ae269422eafb297fc0c6bd79f
Autor:
Zhifen Cui, Yu Zhang, Kai Xia, Qinglong Yan, Huating Kong, Jichao Zhang, Xiaolei Zuo, Jiye Shi, Lihua Wang, Ying Zhu, Chunhai Fan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Arsenic trioxide (ATO) based therapy in solid cancers is limited. Here they repurpose nanodiamonds (NDs) as a safe and potent autophagic inhibitor to improve the efficacy of ATO-based treatment in solid tumors and show the combination therapy to work
Externí odkaz:
https://doaj.org/article/1bf72d2d168c489c90f7ceab014ac31a
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 22529-22543 (2013)
In this study, we investigated the toxic effects of nanocarbon blacks (NCBs) with different sizes to mouse macrophage RAW264.7 cells. MTT and fluorescence-based LIVE assays demonstrated that NCBs uptake caused a size and dose-dependent growth inhibit
Externí odkaz:
https://doaj.org/article/f2b48a229e6245c3844aa829fd652e28
Autor:
Zhong Chen, Zhenqing Ye, Raymond E Soccio, Tomoyoshi Nakadai, William Hankey, Yue Zhao, Furong Huang, Fuwen Yuan, Hongyan Wang, Zhifen Cui, Benjamin Sunkel, Dayong Wu, Richard K Dzeng, Jennifer M Thomas-Ahner, Tim H M Huang, Steven K Clinton, Jiaoti Huang, Mitchell A Lazar, Victor X Jin, Robert G Roeder, Qianben Wang
Publikováno v:
Nucleic acids research. 50(8)
Mediator activates RNA polymerase II (Pol II) function during transcription, but it remains unclear whether Mediator is able to travel with Pol II and regulate Pol II transcription beyond the initiation and early elongation steps. By using in vitro a
Autor:
Zhifen Cui, Cong Zeng, Furong Huang, Fuwen Yuan, Jingyue Yan, Yue Zhao, Yufan Zhou, William Hankey, Victor X. Jin, Jiaoti Huang, Herman F. Staats, Jeffrey I. Everitt, Gregory D. Sempowski, Hongyan Wang, Yizhou Dong, Shan-Lu Liu, Qianben Wang
Publikováno v:
Nat Chem Biol
SARS-CoV-2 entry into cells requires specific host proteases; however, no successful in vivo applications of host protease inhibitors have yet been reported for treatment of SARS-CoV-2 pathogenesis. Here we describe a chemically engineered nanosystem
Autor:
Qinglong Yan, Rui Sun, Zhifen Cui, Jichao Zhang, Yu Zhang, Qi Zhang, Shitai Zhu, Lihua Wang, Qian Li, Min Lu, Ying Zhu, Chunhai Fan
Publikováno v:
Nano Today. 47:101649
Autor:
Xiaolei Zuo, Chunhai Fan, Huating Kong, Yu Zhang, Ying Zhu, Qinglong Yan, Lihua Wang, Jichao Zhang, Jiye Shi, Zhifen Cui, Kai Xia
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Arsenic trioxide (ATO) is a successful chemotherapeutic drug for blood cancers via selective induction of apoptosis; however its efficacy in solid tumors is limited. Here we repurpose nanodiamonds (NDs) as a safe and potent autophagic inhibitor to al
Autor:
Kai Xia, Ali Aldalbahi, Huating Kong, Aiguo Li, Chunhai Fan, Nahed N. E. El-Sayed, Nan Chen, Yan Luo, Jichao Zhang, Zhifen Cui, Yu Zhang, Ying Zhu, Renzhong Tai, Liang Pan
Publikováno v:
Carbon. 111:322-333
Fine particulate matter (PM 2.5) is the principal instigators of adverse health events, yet gaps still remain in understanding the mechanism mediating its toxic response. Similar to nanoparticles, PM 2.5, with large surface area to volume ratio, can
Autor:
Ning Ren, Renduo Liu, Min Lv, Huating Kong, Kai Xia, Qingnuan Li, Lihua Wang, Ying Zhu, Jiye Shi, Chunhai Fan, Yunzhi Cui, Zhifen Cui, Qinglong Yan
Publikováno v:
Nanoscale. 10(37)
Autophagy represents an important cellular response to nanoparticles (NPs), whose modulation holds great promise for developing nanomedicine. Here, we systematically studied cell autophagy responses elicited by the NP-protein corona with diverse prot
Autor:
Chunhai Fan, Zhifen Cui, Qing Huang, Huating Kong, Li XiaoMing, Ying Zhu, Yanhong Sun, Nan Chen, Chun Sheng
Publikováno v:
Chinese Science Bulletin. 58:3521-3529
Autophagy, an important mechanism for maintaining cellular homeostasis, extensively participates in many physiological and pathological processes, and has become one of the hotspots in life sciences research. With more and more extensive application