Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Zhifei Shao"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154802 (2016)
Atherosclerosis is a chronic inflammatory disease with atherosclerotic plaques containing inflammatory cells, including T-lymphocytes, dendritic cells (DCs) and macrophages that are responsible for progression and destabilization of atherosclerotic p
Externí odkaz:
https://doaj.org/article/9214f017e10346a582330fe35c6719b7
Autor:
Masaaki Toda, Zhifei Shao, Ken D Yamaguchi, Takehiro Takagi, Corina N D'Alessandro-Gabazza, Osamu Taguchi, Hugh Salamon, Lawrence L K Leung, Esteban C Gabazza, John Morser
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72392 (2013)
Previously we have shown in a mouse model of bronchial asthma that thrombomodulin can convert immunogenic conventional dendritic cells into tolerogenic dendritic cells while inducing its own expression on their cell surface. Thrombomodulin(+) dendrit
Externí odkaz:
https://doaj.org/article/26e3ed63295d422090cb4d1fac1eb183
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:238-244
BACKGROUND Kallikrein is generated when the contact system is activated, subsequently cleaving high molecular weight kininogen to bradykinin (BK). BK binds to bradykinin receptor 2, causing vascular leakage. BK is inactivated by proteolysis by the pl
Autor:
Zhifei, Shao, Meng Joo, Er
Publikováno v:
International Journal of Intelligent Computing and Cybernetics, 2012, Vol. 5, Issue 3, pp. 293-311.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/17563781211255862
Autor:
Zhifei Shao
Publikováno v:
Advances in Social Science, Education and Humanities Research.
Autor:
Antony Symons, Kaylee Choi, Hyun Yong Jin, Yanyan Tudor, Brian A. Sparling, Zhifei Shao, Joseph G. McGivern
Publikováno v:
SLAS Discovery. 25:215-222
The real-time quantification of target engagement (TE) by small-molecule ligands in living cells remains technically challenging. Systematic quantification of such interactions in a high-throughput setting holds promise for identification of target-s
Autor:
Dawn Weishuhn, Simone Brioschi, Diana Cha, Marco Colonna, Daniel Yoo, Sara Rao, Samuel A. Hasson, Jodi Bradley, Peng Luan, Ian Foltz, Shilpa Sambashivan, Shoutang Wang, Daniel C. Ellwanger, Menno Van Lookeren Campagne, Susan Gilfillan, Palaniswami Rathanaswami, Ryan Case, Lydia Green, Zhifei Shao
Publikováno v:
Proc Natl Acad Sci U S A
Triggering receptor expressed on myeloid cells 2 (TREM2) sustains microglia response to brain injury stimuli including apoptotic cells, myelin damage, and amyloid β (Aβ). Alzheimer’s disease (AD) risk is associated with the TREM2(R47H) variant, w
Autor:
Meng Joo Er, Zhifei Shao
Publikováno v:
Neurocomputing. 194:260-270
It is well known that the Leave-One-Out Cross-Validation (LOO-CV) is a highly reliable procedure in terms of model selection. Unfortunately, it is an extremely tedious method and has rarely been deployed in practical applications. In this paper, a hi
Autor:
Meng Joo Er, Zhifei Shao
Publikováno v:
Neurocomputing. 173:778-788
The Extreme Learning Machine (ELM) is a novel learning scheme for single hidden layer feedforward neural networks, and it has attracted a great deal of research attention since the last decade because of its extremely fast learning speed. One popular
Publikováno v:
Translational Research. 166:89-102
The role of ion channels is largely unknown in chemokine-induced migration in nonexcitable cells such as dendritic cells (DCs). Here, we examined the role of intermediate-conductance calcium-activated potassium channel (KCa3.1) and chloride channel (