Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Zhicong Zhao"'
Autor:
Haiyan Zhang, Xiaojing Luo, Wei Yang, Zhiying Wu, Zhicong Zhao, Xin Pei, Xue Zhang, Chonghao Chen, Josh Haipeng Lei, Qingxia Shi, Qi Zhao, Yanxing Chen, Wenwei Wu, Zhaolei Zeng, Huai-Qiang Ju, Miaozhen Qiu, Jun Liu, Bin Shen, Minshan Chen, Jianjun Chen, Chu-Xia Deng, Rui-Hua Xu, Jiajie Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract RNA methylation is an important regulatory process to determine immune cell function but how it affects the anti-tumor activity of CD8 T cells is not fully understood. Here we show that the N 6-methyladenosine (m6A) RNA reader YTHDF2 is high
Externí odkaz:
https://doaj.org/article/36a9495c82934abdac94acffc6f6a1c2
Autor:
Meilin Xue, Lei Dong, Honghai Zhang, Yangchan Li, Kangqiang Qiu, Zhicong Zhao, Min Gao, Li Han, Anthony K. N. Chan, Wei Li, Keith Leung, Kitty Wang, Sheela Pangeni Pokharel, Ying Qing, Wei Liu, Xueer Wang, Lili Ren, Hongjie Bi, Lu Yang, Chao Shen, Zhenhua Chen, Laleh Melstrom, Hongzhi Li, Nikolai Timchenko, Xiaolan Deng, Wendong Huang, Steven T. Rosen, Jingyan Tian, Lin Xu, Jiajie Diao, Chun-Wei Chen, Jianjun Chen, Baiyong Shen, Hao Chen, Rui Su
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-24 (2024)
Abstract Background While liver cancer stem cells (CSCs) play a crucial role in hepatocellular carcinoma (HCC) initiation, progression, recurrence, and treatment resistance, the mechanism underlying liver CSC self-renewal remains elusive. We aim to c
Externí odkaz:
https://doaj.org/article/b8cac747695b48e59f1516ff7bd9a5a7
Autor:
Zheng Zhang, Keren Zhou, Li Han, Andrew Small, Jianhuang Xue, Huilin Huang, Hengyou Weng, Rui Su, Brandon Tan, Chao Shen, Wei Li, Zhicong Zhao, Ying Qing, Xi Qin, Kitty Wang, Keith Leung, Mark Boldin, Chun-Wei Chen, David Ann, Zhijian Qian, Xiaolan Deng, Jianjun Chen, Zhenhua Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 382-396 (2024)
As the most common internal modification of mRNA, N6-methyladenosine (m6A) and its regulators modulate gene expression and play critical roles in various biological and pathological processes including tumorigenesis. It was reported previously that m
Externí odkaz:
https://doaj.org/article/bd64f8356dfc4a9a8e981d1b56e09447
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 9, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/b08fa2faa44a4bc2b803514b86eb18cc
Autor:
Zhicong Zhao, Chenxi Wang, Jue Jia, Zhaoxiang Wang, Lian Li, Xia Deng, Zhensheng Cai, Ling Yang, Dong Wang, Suxian Ma, Li Zhao, Zhigang Tu, Guoyue Yuan
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 56-68 (2022)
Adipose differentiation and excessive lipid accumulation are the important characteristics of obesity. Metformin, as a classic hypoglycaemic drug, has been proved to reduce body weight in type 2 diabetes, the specific mechanism has not been completel
Externí odkaz:
https://doaj.org/article/81a58149f81d46c599006ec5dbc9666e
Publikováno v:
Genes and Diseases, Vol 9, Iss 3, Pp 697-704 (2022)
This study investigated the role of N6-methyladenosine RNA methylation in liver regeneration following partial hepatectomy in mice. We created a liver-specific knockout mouse model by the deletion of Mettl3, a key component of the N6-methyladenosine
Externí odkaz:
https://doaj.org/article/efa24d3fb0754e71bfe153db7ba2dc76
Autor:
Xia Deng, Chang Guo, Huijuan Qin, Li Zhao, Yanyan Li, Zhicong Zhao, Haoxiang Li, Ling Yang, Dong Wang, Guoyue Yuan
Publikováno v:
Journal of Diabetes Research, Vol 2023 (2023)
Background. Ectodysplasin A (EDA), a member of the TNF family, plays important roles in ectodermal development, while recent studies expanded its regulatory effects on insulin resistance and lipid metabolism. This study was the first time to investig
Externí odkaz:
https://doaj.org/article/dd21169fe8a14575875ee4d992c6d895
Autor:
Li Zhao, Yue Qiu, Panpan Zhang, Xunan Wu, Zhicong Zhao, Xia Deng, Ling Yang, Dong Wang, Guoyue Yuan
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Except for improving glycemic control, liraglutide, one of the glucagon-like peptide-1 receptor agonists, has exerted promising therapeutic effects for dyslipidemia. It has been proved that gut microbiota plays a dramatic role in regulating lipid met
Externí odkaz:
https://doaj.org/article/7d69952e35f64264b87386a7a80987c8
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The ATP binding cassette (ABC) transporter family is ubiquitous in eukaryotes, specifically in vertebrates, and plays a crucial role in energy homeostasis, cell signaling, and drug resistance. Accumulating evidence indicates that some ABC transporter
Externí odkaz:
https://doaj.org/article/0e171e5f84eb40a4a5b6a64502bfd8c5
Autor:
Jue Jia, Ruoshuang Liu, Weiping Wei, Fan Yu, Xiawen Yu, Yirong Shen, Caiqin Chen, Zhensheng Cai, Chenxi Wang, Zhicong Zhao, Dong Wang, Ling Yang, Guoyue Yuan
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Recently, monocyte to high-density lipoprotein cholesterol ratio (MHR) as a novel inflammatory biomarker has drawn lots of attention. This study was conducted in patients with type 2 diabetes mellitus (T2DM) to investigate the correlation
Externí odkaz:
https://doaj.org/article/471c66ce15b947288f115301b34c19cc