Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Zhichao Lang"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Long noncoding RNA small nucleolar RNA host gene 5 (SNHG5) is an oncogene found in various human cancers. However, it is unclear what role SNHG5 plays in activating hepatic stellate cells (HSCs) and liver fibrosis. In this study, SNHG5 was f
Externí odkaz:
https://doaj.org/article/5585681571dd4c89b66f856054484a81
Autor:
Zhenxu Zhou, Rongrong Zhang, Xinmiao Li, Weizhi Zhang, Yating Zhan, Zhichao Lang, Qiqi Tao, Jinglu Yu, Suhui Yu, Zhengping Yu, Jianjian Zheng
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Hepatic stellate cell (HSC) activation is considered as a central driver of liver fibrosis and effective suppression of HSC activation contributes to the treatment of liver fibrosis. Circular RNAs (circRNAs) have been reported to be importan
Externí odkaz:
https://doaj.org/article/e2bc0189bc314c579cbb0ac5115736e3
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 5, Pp 100902- (2024)
Liver fibrosis is primarily driven by the activation of hepatic stellate cells (HSCs), a process associated with ferroptosis. Ginsenoside Rb1 (GRb1), a major active component extracted from Panax ginseng, inhibits HSC activation. However, the potenti
Externí odkaz:
https://doaj.org/article/ab6deddcd7d7446fa65502d7a38560e9
Autor:
Qiqi Tao, Zhichao Lang, Yifei Li, Yuxiang Gao, Lifan Lin, Zhengping Yu, Jianjian Zheng, Suhui Yu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Necroptosis has been reported to be involved in cancer progression and associated with cancer prognosis. However, the prognostic values of necroptosis-related genes (NRGs) in hepatocellular carcinoma (HCC) remain largely unknown. This study
Externí odkaz:
https://doaj.org/article/a38b2b8e1706401f83f41d8f4ecccfc3
Autor:
Zhichao Lang, Yifei Li, Lifan Lin, Xinmiao Li, Qiqi Tao, Yuhang Hu, Menglu Bao, Lei Zheng, Zhengping Yu, Jianjian Zheng
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Recently, Salidroside (Sal) has been demonstrated to suppress hepatic stellate cell (HSC) activation, a crucial event for liver fibrosis. Moreover, Sal has been reported to decrease hepatocyte injury. A growing number of reports have indicat
Externí odkaz:
https://doaj.org/article/cde14952e0f8495e9894ea1a041cb3e8
Autor:
Rongrong Zhang, Xinmiao Li, Yuxiang Gao, Qiqi Tao, Zhichao Lang, Yating Zhan, Chunxue Li, Jianjian Zheng
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 4, Pp 534-542 (2023)
Background: Ginsenoside Rg1, a bioactive component of Ginseng, has demonstrated anti-inflammatory, anti-cancer, and hepatoprotective effects. It is known that the epithelial–mesenchymal transition (EMT) plays a key role in the activation of hepatic
Externí odkaz:
https://doaj.org/article/2c10988ecc9b483d9fcdee4ef1506e09
Publikováno v:
Journal of Ginseng Research, Vol 47, Iss 4, Pp 515-523 (2023)
Background: 20(S)-protopanaxadiol (PPD), one of the main components of ginseng, has anti-inflammatory, anti-estrogenic, and anti-tumor activities. It is known that activated hepatic stellate cells (HSCs) are the primary producers of extracellular mat
Externí odkaz:
https://doaj.org/article/308bd3bac6bf4c209b06e846e41f8475
Autor:
Xiaodong Wang, Ji Chen, Lifan Lin, Yifei Li, Qiqi Tao, Zhichao Lang, Jianjian Zheng, Zhengping Yu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract As a highly heterogeneous cancer, the prognostic stratification and personalized management of hepatocellular carcinoma (HCC) are still challenging. Recently, Antigen-presenting-cells (APCs) and T-cells-infiltration (TCI) have been reported
Externí odkaz:
https://doaj.org/article/484314ba3c7e4a62ba5a7f4dd77bc360
Autor:
Zhichao Lang, Rongrong Zhang, Xinmiao Li, Yan Jin, Yuhang Hu, Xinyi Lin, Yunzhi Tang, Jingnan Zhang, Lei Zheng, Zhixian Yu, Jianjian Zheng
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107326- (2023)
Summary: Hepatocyte pyroptosis has been shown to be involved in liver damage progression. Previously, we found that growth arrest-specific 5 (GAS5) is a regulator of hepatic stellate cell (HSC) activation. However, whether GAS5 plays a role in hepato
Externí odkaz:
https://doaj.org/article/66fe7ddf062c4c04a4a1c04a3b22dcd3
Autor:
Bo Chen, Zhan Yang, Zhichao Lang, Qiqi Tao, Rongrong Zhang, Yating Zhan, Xuantong Xu, Kai Zhu, Jianjian Zheng, Zhengping Yu, Suhui Yu
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract LncRNA N6-methylandenosine (m6A) modification has been shown to be associated with the constitution of the tumor microenvironment (TME) and tumorigenesis. It’s essential to understand the mechanisms of lncRNA m6A modification in hepatocell
Externí odkaz:
https://doaj.org/article/87fc43e870894655946d490a2cf295e5