Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Zhibo Kong"'
Autor:
Xiaoping Min, Chongzhou Yang, Jun Xie, Yang Huang, Nan Liu, Xiaocheng Jin, Tianshu Wang, Zhibo Kong, Xiaoli Lu, Shengxiang Ge, Jun Zhang, Ningshao Xia
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Natural proteins occupy a small portion of the protein sequence space, whereas artificial proteins can explore a wider range of possibilities within the sequence space. However, specific requirements may not be met when generating
Externí odkaz:
https://doaj.org/article/1016db6fe276401eae6765f8e74a89ee
Autor:
Yang Huang, Hui Sun, Shuzhen Wei, Lanlan Cai, Liqin Liu, Yanan Jiang, Jiabao Xin, Zhenqin Chen, Yuqiong Que, Zhibo Kong, Tingting Li, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Shaowei Li, Rui Zhang, Ningshao Xia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tailed bacteriophages (order, Caudovirales) account for the majority of all phages. However, the long flexible tail of siphophages hinders comprehensive investigation of the mechanism of viral gene delivery. Here, we report the atomic capsid
Externí odkaz:
https://doaj.org/article/cd8e45dd2bbe416fb310773c90009e58
Autor:
Guosong Wang, Zhenghui Zha, Pengfei Huang, Hui Sun, Yang Huang, Maozhou He, Tian Chen, Lina Lin, Zhenqin Chen, Zhibo Kong, Yuqiong Que, Tingting Li, Ying Gu, Hai Yu, Jun Zhang, Qingbing Zheng, Yixin Chen, Shaowei Li, Ningshao Xia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Pseudorabies virus (PRV) is a major etiological agent of swine infectious diseases responsible for significant economic losses in the swine industry. The authors report the structures of the PRV A-capsid and C-capsid, shedding light on PRV’s assemb
Externí odkaz:
https://doaj.org/article/c1c0f7afda504519bbcbcb4b690ffa07
Autor:
Yang Huang, Zizhen Li, Qiyang Hong, Lizhi Zhou, Yue Ma, Yisha Hu, Jiabao Xin, Tingting Li, Zhibo Kong, Qingbing Zheng, Yixin Chen, Qinjian Zhao, Ying Gu, Jun Zhang, Yingbin Wang, Hai Yu, Shaowei Li, Ningshao Xia
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 710-720 (2022)
Conformational changes or rearrangements are common events during inter-biomolecular recognition. Tracking these changes are essential for exploring the allosteric mechanism and it is usually achieved by molecular dynamics simulation in silico. We pr
Externí odkaz:
https://doaj.org/article/c0d3d8b137954bb09e7f181f8fee3c02
Autor:
Kaihang Wang, Lizhi Zhou, Tingting Chen, Qiong Li, Jiajia Li, Liqin Liu, Yuqian Li, Jie Sun, Tingting Li, Yingbin Wang, Zhibo Kong, Qingbing Zheng, Jun Zhang, Hai Yu, Ying Gu, Ningshao Xia, Shaowei Li
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background The various advantages associated with the growth properties of Escherichia coli have justified their use in the production of genetically engineered vaccines. However, endotoxin contamination, plasmid vector instability, and the
Externí odkaz:
https://doaj.org/article/5eeaef31a5954d8e82cf6b8397ff5bba
Autor:
Liqin Liu, Tingting Chen, Lizhi Zhou, Jie Sun, Yuqian Li, Meifeng Nie, Hualong Xiong, Yuhe Zhu, Wenhui Xue, Yangtao Wu, Tingting Li, Tianying Zhang, Zhibo Kong, Hai Yu, Jun Zhang, Ying Gu, Qingbing Zheng, Qinjian Zhao, Ningshao Xia, Shaowei Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The Coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented public health crisis worldwide. Although several vaccines are available, the global supply of vaccines, particularly within developing countries, is inadequate, and this neces
Externí odkaz:
https://doaj.org/article/51a2abad0eee44b1bf5241b66035a219
Autor:
Daning Wang, Xinlin Liu, Minxi Wei, Ciying Qian, Shuo Song, Jie Chen, Zhiping Wang, Qin Xu, Yurou Yang, Maozhou He, Xin Chi, Shiwen Huang, Tingting Li, Zhibo Kong, Qingbing Zheng, Hai Yu, Yingbin Wang, Qinjian Zhao, Jun Zhang, Ningshao Xia, Ying Gu, Shaowei Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
An effective vaccine for human papillomavirus (HPV) needs to protect from several genotypes. Here, Wang et al. provide a strategy to produce single capsomere-hybrid virus-like particle (chVLP) composed of capsomers of different genotypes and show tha
Externí odkaz:
https://doaj.org/article/a48ad75cb64149f78c08387b5f6a5505
Autor:
Lizhi Zhou, Hai Yu, Kaihang Wang, Tingting Chen, Yue Ma, Yang Huang, Jiajia Li, Liqin Liu, Yuqian Li, Zhibo Kong, Qingbing Zheng, Yingbin Wang, Ying Gu, Ningshao Xia, Shaowei Li
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The Escherichia coli ER2566 strain (NC_CP014268.2) was developed as a BL21 (DE3) derivative strain and had been widely used in recombinant protein expression. However, like many other current RefSeq annotations, the annotation of
Externí odkaz:
https://doaj.org/article/388fd0938fdc4f28a0ae8428109a789c
Autor:
Xinlin Liu, Jie Chen, Zhiping Wang, Daning Wang, Maozhou He, Ciying Qian, Shuo Song, Xin Chi, Zhibo Kong, Qingbing Zheng, Yingbin Wang, Hai Yu, Qinjian Zhao, Jun Zhang, Shaowei Li, Ying Gu, Ningshao Xia
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1721-1733 (2019)
ABSTRACTHuman papillomavirus type 6 (HPV6) is the major etiologic agent of genital warts and recurrent respiratory papillomatosis. Although the commercial HPV vaccines cover HPV6, the neutralization sites and mode for HPV6 are poorly understood. Here
Externí odkaz:
https://doaj.org/article/127e331dfd4b48a9bc1feb13a471f194
Autor:
Daning Wang, Zhihai Li, Jieqiong Xiao, Junqi Wang, Li Zhang, Yajing Liu, Fei Fan, Lu Xin, Minxi Wei, Zhibo Kong, Hai Yu, Ying Gu, Jun Zhang, Shaowei Li, Ningshao Xia
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123944 (2015)
Human Papillomavirus (HPV), a non-enveloped, double-stranded DNA virus, is responsible for 5% of human cancers. The HPV capsid consists of major and minor structural proteins, L1 and L2. L1 proteins form an icosahedral shell with building blocks of t
Externí odkaz:
https://doaj.org/article/830c66ab9d39453a9771158bd6a382e4