Zobrazeno 1 - 10
of 78
pro vyhledávání: '"ZhiChong Wu"'
Autor:
Lijie Han, Yongsheng Jiang, Minmin Shi, Lina Gan, Zhichong Wu, Meilin Xue, Youwei Zhu, Cheng Xiong, Ting Wang, Xiaozhu Lin, Baiyong Shen, Lingxi Jiang, Hao Chen
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background LIPH, a membrane-associated phosphatidic acid-selective phospholipase A1a, can produce LPA (Lysophosphatidic acid) from PA (Phosphatidic acid) on the outer leaflet of the plasma membrane. It is well known that LIPH dysfunction con
Externí odkaz:
https://doaj.org/article/6b4014868f7248958e242a57ec94b233
Autor:
Zhichong Wu, Kenneth Guangpu Yang, Tsz-Ping Lam, Jack Chun Yiu Cheng, Zezhang Zhu, Wayne Yuk-Wai Lee
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Osteoporosis is a major causative factor of the global burden of disease and disability, characterized by low bone mineral density (BMD) and high risks of fracture. We aimed to identify putative causal proteins and druggable targets of os
Externí odkaz:
https://doaj.org/article/24e69cb3711547b49437e23f0f7ae965
Autor:
Zhichong Wu, Zhenhua Feng, Xiufen Zhu, Zhicheng Dai, Kaixing Min, Yong Qiu, Long Yi, Leilei Xu, Zezhang Zhu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background X-linked early-onset osteoporosis, caused by mutations in plastin3 (PLS3), is an extremely rare disease characterized by low bone mineral density (BMD) and recurrent osteoporotic fractures. There is limited information on genetic
Externí odkaz:
https://doaj.org/article/2864c01591434a31b7feb400be7ee250
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Background Abnormal metabolic features have been previously described in adolescent idiopathic scoliosis (AIS) patients. As an important regulator involved in energy metabolism, DPP-4 activity was reported to be remarkably decreased in osteo
Externí odkaz:
https://doaj.org/article/36d5b5976edf475ea305cf03bf1eee09
Autor:
Yuwen Wang, Zhicheng Dai, Zhichong Wu, Zhenhua Feng, Zhen Liu, Xu Sun, Leilei Xu, Yong Qiu, Zezhang Zhu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-6 (2021)
Abstract Background A recent genome-wide association study identified a susceptible locus in MIR4300HG gene that was associated with curve progression of adolescent idiopathic scoliosis (AIS) in the Japanese population. However, the association betwe
Externí odkaz:
https://doaj.org/article/5b0c401220354830927cf1a7f3f37624
Autor:
Deborah Fanfone, Zhichong Wu, Jade Mammi, Kevin Berthenet, David Neves, Kathrin Weber, Andrea Halaburkova, François Virard, Félix Bunel, Catherine Jamard, Hector Hernandez-Vargas, Stephen WG Tait, Ana Hennino, Gabriel Ichim
Publikováno v:
eLife, Vol 11 (2022)
Mechanical stress is known to fuel several hallmarks of cancer, ranging from genome instability to uncontrolled proliferation or invasion. Cancer cells are constantly challenged by mechanical stresses not only in the primary tumour but also during me
Externí odkaz:
https://doaj.org/article/f33cdea831cd4345a18c8c0bfc588ea6
Autor:
Sophie Bachy, Zhichong Wu, Pia Gamradt, Kevin Thierry, Pascale Milani, Julien Chlasta, Ana Hennino
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103758- (2022)
Summary: Macrophages play an important role in immune and matrix regulation during pancreatic adenocarcinoma (PDAC). Collagen deposition massively contributes to the physical and functional changes of the tissue during pathogenesis. We investigated t
Externí odkaz:
https://doaj.org/article/ef3810f05e5e47c1b737e17deb71f67a
Autor:
Leilei Xu, Zhenhua Feng, Zhicheng Dai, Wayne Y. W. Lee, Zhichong Wu, Zhen Liu, Xu Sun, Nelson Tang, Jack Chun-Yiu Cheng, Yong Qiu, Zezhang Zhu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Previous studies have shown that LBX1 is associated with adolescent idiopathic scoliosis (AIS) in multiple populations. For the first time, rs1322330 located in the putative promoter region of LBX1 was found significantly associated with AIS in the C
Externí odkaz:
https://doaj.org/article/20fc9b81b1a04d438c3e7eda83557c61
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Background Infantile patients with congenital scoliosis (CS) can be confronted with increasing risk of mortality and morbidity. To date, the effectiveness of conservative treatment in CS has not been sufficiently investigated. We aimed to ev
Externí odkaz:
https://doaj.org/article/71d78e49dc104d42ac2e4d05814934c7
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100066- (2021)
Externí odkaz:
https://doaj.org/article/7a62c47c5af74269b2c8260cb92587db