Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Zhi-xue Cheng"'
Autor:
Zhi-xue Cheng, Chang Guo, Zhuang-gui Chen, Tian-ci Yang, Jian-ying Zhang, Jie Wang, Jia-xin Zhu, Dan Li, Tian-tuo Zhang, Hui Li, Bo Peng, Xuan-xian Peng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Serum-resistant bacteria can escape complement killing in the bloodstream. Here, using metabolomics and metabolite perturbations, the authors describe an altered metabolic state in serum-resistant Escherichia coli and show that exogenous glycine pote
Externí odkaz:
https://doaj.org/article/2a81a06532b8422685249d3fbec16fbf
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 634-644 (2018)
Vibrio alginolyticus is a waterborne pathogen that infects a wide variety of hosts including fish and human, and the outbreak of this pathogen can cause a huge economic loss in aquaculture. Thus, enhancing host's capability to survive from V. alginol
Externí odkaz:
https://doaj.org/article/06a3b3e5b8d54d77bac84f3da71df9cd
Autor:
Zhi-xue Cheng, Qi-yang Gong, Zhe Wang, Zhuang-gui Chen, Jin-zhou Ye, Jun Li, Jie Wang, Man-jun Yang, Xiao-peng Ling, Bo Peng
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Evasion of complement-mediated killing is a common phenotype for many different types of pathogens, but the mechanism is still poorly understood. Most of the clinic isolates of Edwardsiella tarda, an important pathogen infecting both of human and fis
Externí odkaz:
https://doaj.org/article/7893ecd75d5c4ff591d21d4308712838
Autor:
Xian-liang Zhao, Zhuang-gui Chen, Tian-ci Yang, Ming Jiang, Jie Wang, Zhi-xue Cheng, Man-jun Yang, Jia-xin Zhu, Tian-tuo Zhang, Hui Li, Bo Peng, Xuan-xian Peng
Publikováno v:
Science Translational Medicine. 13
The prevalence of multidrug-resistant bacteria has been increasing rapidly worldwide, a trend that poses great risk to human and animal health and creates urgent need for pharmaceutical and nonpharmaceutical approaches to stop the spread of disease d
Autor:
Jianying Zhang, Jia-xin Zhu, Jie Wang, Tian-Tuo Zhang, Chang Guo, Hui Li, Bo Peng, Dan Li, Tian-ci Yang, Xuan-xian Peng, Zhi-xue Cheng, Zhuang-Gui Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Serum resistance is a poorly understood but common trait of some difficult-to-treat pathogenic strains of bacteria. Here, we report that glycine, serine and threonine catabolic pathway is down-regulated in serum-resistant Escherichia coli, whereas ex
Publikováno v:
Fish & Shellfish Immunology. 84:912-919
Antibiotic-resistant bacteria becomes a major threat to the economy and food safety in aquaculture. Although the antibiotic-dependent strategy is still the mostly adopted option, the development of antibiotic-free approach is urgently needed to ameli
Publikováno v:
Environmental Microbiology. 20:4022-4036
The development of antibiotic resistance in Vibrio alginolyticus represents a threat to human health and fish farming. Environmental NaCl regulation of bacterial physiology is well documented, but whether the regulation contributes to antibiotic resi
Publikováno v:
Fish & Shellfish Immunology. 75:308-315
Polyvalent vaccines against more than one species of pathogens are especially important due to the complex ecosystem in aquaculture. We have previously shown that the development of polyvalent vaccines by shuffling six ompA genes from different bacte
Publikováno v:
Fish & Shellfish Immunology. 74:325-331
Our previous studies demonstrated that molecular breeding via DNA shuffling directs the evolution of polyvalent vaccines with desired traits, which leads to generation of polyvalent ompA vaccines using Vibrio alginolyticus VA0764 primers. Here, we re
Publikováno v:
Journal of Proteome Research. 15:2246-2253
Streptococcus agalactiae causes severe systemic infections in human and fish. In the present study, we established a pathogen-plasma interaction model by which we explored how S. agalactiae evaded serum-mediated killing. We found that S. agalactiae g