Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zhi-jian Yu"'
Bmal1 haploinsufficiency impairs fear memory and modulates neuroinflammation via the 5-HT2C receptor
Autor:
Weifen Li, Shengnan Mou, Tahir Ali, Tianxiang Li, Yan Liu, Shupeng Li, Xiaoming Yu, Zhi-Jian Yu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundBMAL1, a key regulator of circadian rhythms, plays a multifaceted role in brain function. However, the complex interplay between BMAL1, memory, neuroinflammation, and neurotransmitter regulation remains poorly understood. To investigate the
Externí odkaz:
https://doaj.org/article/f0ab59b4e7394795a3a593bcaa25a065
Autor:
Kaiwu He, Lulin Nie, Tahir Ali, Zizhen Liu, Weifen Li, Ruyan Gao, Zena Zhang, Jianjun Liu, Zhongliang Dai, Yongmei Xie, Zaijun Zhang, Gongping Liu, Ming Dong, Zhi-Jian Yu, Shupeng Li, Xifei Yang
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background A wide spectrum of changes occurs in the brain with age, from molecular to morphological aspects, and inflammation accompanied by mitochondria dysfunction is one of the significant factors associated with age. Adiponectin (APN), a
Externí odkaz:
https://doaj.org/article/bef7bd9f1a1e4a68bb8431eaa56116a4
Autor:
Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Qingguo Ren, Shafiq Ur Rahman, Ningning Li, Zhi-Jian Yu, Shupeng Li
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/d3944b2d9791412eaa27348b4b54b9e1
Autor:
Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Qingguo Ren, Shafiq Ur Rahman, Ningning Li, Zhi-Jian Yu, Shupeng Li
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Selective serotonin reuptaker inhibitors, including fluoxetine, are widely studied and prescribed antidepressants, while their exact molecular and cellular mechanism are yet to be defined. We investigated the involvement of HDAC1
Externí odkaz:
https://doaj.org/article/7b8cb0bea14348edbd78c97149bceef9
Autor:
Fan Zhang, Bing Bai, Guang-jian Xu, Zhi-wei Lin, Gui-qiu Li, Zhong Chen, Hang Cheng, Xiang Sun, Hong-yan Wang, Yan-wei Chen, Jin-xin Zheng, Qi-wen Deng, Zhi-jian Yu
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Mortality rates for patients with Staphylococcus aureus (S. aureus) infections have improved only modestly in recent decades and S. aureus infections remain a major clinical challenge This study investigated the in vitro antimicro
Externí odkaz:
https://doaj.org/article/cf0dc8c1f5994d97ab60d694001ca424
Autor:
Zhi-wei Lin, Jin-xin Zheng, Bing Bai, Guang-jian Xu, Fo-jun Lin, Zhong Chen, Xiang Sun, Di Qu, Zhi-jian Yu, Qi-wen Deng
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) has been increasingly reported and is now recognized as a significant threat to public health; however, characterization of MDR-hvKP has not been systematically investigated. In the p
Externí odkaz:
https://doaj.org/article/4ba35d0f85094416a631804f02a1716a
Autor:
Zhi-Jian Yu, Lu Zeng, Xiang-Qian Luo, Xiao-Rui Geng, Rui Xu, Kun Chen, Gui Yang, Xi Luo, Zhi-Qiang Liu, Zhi-Gang Liu, Da-Bo Liu, Ping-Chang Yang, Hua-Bin Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract It is recognized that T helper 2 (Th2) polarization plays a critical role in a large number of immune disorders. Yet, the remedies for reconciling the established Th2 polarization are still limited currently. Published data indicate that mic
Externí odkaz:
https://doaj.org/article/f2861f79c8cc4e6ca5921d98374e8606
Autor:
Jin-xin Zheng, Zhi-wei Lin, Chen Chen, Zhong Chen, Fo-jun Lin, Yang Wu, Si-yu Yang, Xiang Sun, Wei-ming Yao, Duo-yun Li, Zhi-jian Yu, Jia-lin Jin, Di Qu, Qi-wen Deng
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Klebsiella pneumoniae bacteremia biofilm traits and distribution characteristics have not been clarified. This study aimed to determine the prevalence and characteristics of K. pneumoniae bacteremia biofilm formation (BF) and to explore the virulence
Externí odkaz:
https://doaj.org/article/095e2503398347b1b8fb205e1010eec1
Autor:
Kai-tao Hu, Jin-xin Zheng, Zhi-jian Yu, Zhong Chen, Hang Cheng, Wei-guang Pan, Wei-zhi Yang, Hong-yan Wang, Qi-wen Deng, Zhong-ming Zeng
Publikováno v:
International Journal of Infectious Diseases, Vol 33, Iss C, Pp 32-36 (2015)
Objectives: Sucrose gel was used to treat bacterial vaginosis in a phase III clinical trial. However, the changes of vaginal flora after treatment were only examined by Nugent score in that clinical trial, While the vaginal microbiota of rhesus macaq
Externí odkaz:
https://doaj.org/article/81c1683659244aee9b024033c99ea1e6
Autor:
Jin-Xin Zheng, Yang Wu, Zhi-Wei Lin, Zhang-Ya Pu, Wei-Ming Yao, Zhong Chen, Duo-Yun Li, Qi-Wen Deng, Di Qu, Zhi-Jian Yu
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Enterococcus faecalis biofilm traits and distribution characteristics in China have not been clarified. This study aimed to determine the prevalence and characteristics of E. faecalis biofilm formation in a sample of clinical isolates and to explore
Externí odkaz:
https://doaj.org/article/df0d8fc4fba0472f90096ce4df4bb4ed