Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Zhi-jia Wang"'
Autor:
Da-Yong Hou, Dong-Bing Cheng, Ni-Yuan Zhang, Zhi-Jia Wang, Xing-Jie Hu, Xin Li, Mei-Yu Lv, Xiang-Peng Li, Ling-Rui Jian, Jin-Peng Ma, Taolei Sun, Zeng-Ying Qiao, Wanhai Xu, Hao Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4 (GPX4) inhibitors may be a prominent therapeutic strategy for tumor suppression. However, the wide application of GPX4 inhibitors in tumor therapy is
Externí odkaz:
https://doaj.org/article/35f9a585649e480eac19b76f73b79d50
Autor:
Da-Yong Hou, Man-Di Wang, Xing-Jie Hu, Zhi-Jia Wang, Ni-Yuan Zhang, Gan-Tian Lv, Jia-Qi Wang, Xiu-Hai Wu, Lu Wang, Hao Wang, Wanhai Xu
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 110-119 (2022)
Intraoperative fluorescence-based tumor imaging plays a crucial role in performing the oncological safe tumor resection with the advantage of differentiating tumor from normal tissues. However, the application of these fluorescence contrast agents in
Externí odkaz:
https://doaj.org/article/c7e50f66da344a80b6f837f934eeec15
Publikováno v:
Shock and Vibration, Vol 2021 (2021)
The combined retaining structure has gradually received considerable attention in the slope engineering, due to its good reinforcement effects. However, most of the published research studies were focused on the seismic responses of the single-formal
Externí odkaz:
https://doaj.org/article/bba7cc7e1f1b4cd6b0a9e3c72bfe5933
Autor:
Da-Yong Hou, Man-Di Wang, Ni-Yuan Zhang, Shaoxin Xu, Zhi-Jia Wang, Xing-Jie Hu, Gan-Tian Lv, Jia-Qi Wang, Mei-Yu Lv, Li Yi, Lu Wang, Dong-Bing Cheng, Taolei Sun, Hao Wang, Wanhai Xu
Publikováno v:
Nano Letters. 22:3983-3992
Lysosome-targeting self-assembling prodrugs had emerged as an attractive approach to overcome the acquisition of resistance to chemotherapeutics by inhibiting lysosomal sequestration. Taking advantage of lysosomal acidification induced intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c40bf24755eddb881a2d528bd450008
https://doi.org/10.1021/acs.nanolett.2c00540
https://doi.org/10.1021/acs.nanolett.2c00540
Autor:
Hong-Wei An, Da-Yong Hou, Jia Yang, Zi-Qi Wang, Man-Di Wang, Rui Zheng, Ni-Yuan Zhang, Xing-Jie Hu, Zhi-Jia Wang, Lu Wang, Di Liu, Jun-Feng Hao, Wanhai Xu, Yuliang Zhao, Hao Wang
Publikováno v:
Science Advances. 9
Up to 75% of bladder cancer patients suffer from recurrence due to postoperative tumor implantation. However, clinically used Bacillus Calmette-Guerin (BCG) treatment failed to inhibit the recurrence. Here, we report a bispecific glycopeptide (bsGP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6f9ad71ac6d0f0099717d8e6179f47f
https://doi.org/10.1126/sciadv.abq8225
https://doi.org/10.1126/sciadv.abq8225
Publikováno v:
Journal of Mountain Science. 18:2460-2474
Physical model test is an effective way to unveil the dynamic response of a slope under seismic condition. The similarity design is the key of physical model test. An isolated similarity design method for shaking table tests was proposed and verified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05aa372aaba3b3da50d840253d73716e
https://doi.org/10.1007/s11629-020-6398-3
https://doi.org/10.1007/s11629-020-6398-3
Autor:
Bo Feng, Wen-Long Wang, Zhi-Jia Wang, Yubo Zhou, Rajendran Satheeshkumar, Xu-Yang Mu, Jia Li, Li-Xin Gao, Lei Xu
Publikováno v:
RSC Advances. 11:3216-3220
A series of 2-ethoxycarbonylthieno[2,3-b]quinolines were synthesized in the bio-derived “green” solvent γ-valerolactone (GVL) and evaluated for their inhibitory activities against PTP1B, the representative compound 6a displayed an IC50 value of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c98e667273c1017b6067dde2a582531
https://doi.org/10.1039/d0ra09247a
https://doi.org/10.1039/d0ra09247a
Autor:
Yubo Zhou, Zhi-jia Wang, Yu-qi Xiang, Hu Xiaobei, Tiancheng Dong, Wen-Biao Wu, Lei Xu, Kan Weijuan, Jia Li, Hanlin Wang, Bo Feng, Jia-Nan Li, Anhui Gao, Xiaotuan Zhang, Chunmei Xia
Publikováno v:
Acta Pharmacol Sin
Diffuse large B-cell lymphoma (DLBCL) is the most widespread type of non-Hodgkin lymphoma (NHL). As the most aggressive form of the DLBCL, the activated B-cell-like (ABC) subtype is often resistant to standard chemotherapies. Bruton’s tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe1990e2386952f66b02ce8ceae19bf
https://doi.org/10.1038/s41401-020-00505-3
https://doi.org/10.1038/s41401-020-00505-3
Autor:
Da‐Yong Hou, Ni‐Yuan Zhang, Man‐Di Wang, Shao‐Xin Xu, Zhi‐Jia Wang, Xing‐Jie Hu, Gan‐Tian Lv, Jia‐Qi Wang, Xiu‐Hai Wu, Lu Wang, Dong‐Bing Cheng, Hao Wang, Wanhai Xu
Publikováno v:
Angewandte Chemie. 134
Intravesical administration of first-line drugs has shown failure in the treatment of bladder cancer owing to the poor tumor retention time of chemotherapeutics. Herein, we report an intracellular hydrolytic condensation (IHC) system to construct lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f07fa68d587319fd8302c860e6b82f
https://doi.org/10.1002/ange.202116893
https://doi.org/10.1002/ange.202116893
Autor:
Dayong Hou, Man-Di Wang, Ni-Yuan Zhang, Hao Wang, Gan-Tian Lv, Wanhai Xu, Xing-Jie Hu, Li Yi, Ru-Xiang Li, Zhi-Jia Wang
Publikováno v:
Biomaterials. 278
Peptide drug conjugate (PDC) has emerged as one of the new generations of targeted therapeutics for cancer, which owns the advantages of improved drug targetability and reduced adverse effects compared with traditional chemotherapy. However, the poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4907abf1ef6f861e25c5cda78022f4f
https://pubmed.ncbi.nlm.nih.gov/34624753
https://pubmed.ncbi.nlm.nih.gov/34624753