Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zhi-hua Yu"'
Autor:
Jia-Bing Li, Xiao-Yu Hu, Mu-Wen Chen, Cai-Hong Xiong, Na Zhao, Yan-Hui Ge, Hao Wang, Xiao-Ling Gao, Nan-Jie Xu, Lan-Xue Zhao, Zhi-Hua Yu, Hong-Zhuan Chen, Yu Qiu
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-18 (2023)
Abstract Background Ribosomal protein S6 kinase 1 (S6K1) is a serine–threonine kinase that has two main isoforms: p70S6K (70-kDa isoform) and p85S6K (85-kDa isoform). p70S6K, with its upstream mammalian target of rapamycin (mTOR), has been shown to
Externí odkaz:
https://doaj.org/article/7a4fe3561f9847d4b6ecb9f8834498b3
Autor:
Zhao-Guo Li, Bai-Cun Li, Zhi-Wei Li, Hui-Yuan Hu, Xia Ma, Hong Cao, Zhi-Hua Yu, Hua-Ping Dai, Jing Wang, Chen Wang
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Evidence suggests that exposure to coal dust increases immunoglobulin concentration. However, there is a paucity of data reporting immunoglobulin G (IgG) subclass in coal workers’ pneumoconiosis (CWP). Therefore, this study intended to evaluate pot
Externí odkaz:
https://doaj.org/article/828906b3d9f2469fbff26f569119bd49
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Sleep disturbances not only deteriorate Alzheimer’s disease (AD) progress by affecting cognitive states but also accelerate the neuropathological changes of AD. Astrocytes and microglia are the principal players in the regulation of both sleep and
Externí odkaz:
https://doaj.org/article/f6ee3269b3794ac487cb273238845159
Publikováno v:
Journal of Physics: Conference Series. 1738:012055
This paper presents a novel method of distinguishing signal, the way expected to reduce the nuisance alarm rate since the high nuisance alarm rate will restrict the capability of phase-sensitive optical time-domain reflection technology. The proposed
Autor:
Fang-fang Mou, Hai-dong Guo, Li-sheng Zhang, Shui-jin Shao, Guo-hong Cui, Xiao-jing Han, Yan-wu Xu, Jin-xin Tian, Jing Zhu, Da-yong Zhang, Zhi-hua Yu, Jiu-lin Chen
Publikováno v:
Acupuncture in Medicine. 34:449-456
Background Acupuncture is a potential therapy for Alzheimer's disease (AD), but its clinical effects and underlying mechanisms are not fully understood. Emerging evidence suggests autophagy is involved in β-amyloid (Aβ) clearance. We hypothesised t
Autor:
Juan-Juan Lu, Yun Song, Yong-Yao Cui, Ping Yu, Liang Zhu, Hao-Zhong Lu, Zhi-Hua Yu, Hong-Zhuan Chen
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 39:38-47
Steroid insensitivity has been commonly found in chronic obstructive pulmonary disease (COPD) patients, which is mediated by the reduction of histone deacetylase (HDAC) 2. Here we aimed to establish a steroid resistant model on experimental COPD rats
Publikováno v:
Advanced Materials Research. 1081:151-155
In order to solve the difficulty of how nanoTiO2 could penetrate and fixate in polypropylene fiber, the study was carried out by using supercritical CO2 as an assistant method. According to the experiments, the stable nanoTiO2 dispersion could be obt
Publikováno v:
Advanced Materials Research. 859:100-104
In allusion to double sheet piles(DSP) global optimal solution, the response surface(RS) technique based on Uniform Design- Support Vector Machine(UD-SVM) was introduced to build the RS by nonparametric regression, thus to avoid the complex non-linea
Publikováno v:
European Journal of Organic Chemistry. 2014:583-591
Diverse chromenones were synthesized through tunable phosphine-mediated cascade reactions between 3-acyl-2H-chromen-2-ones and Morita–Baylis–Hillman (MBH) derivatives. With different phosphine loadings and reaction temperatures, MBH derivatives a
Publikováno v:
Tetrahedron. 69:8137-8141
Multi-substituted quinolines 3 were unexpectedly prepared from a cascade reaction of ortho-azido-β-nitro-styrenes with various carbonyl compounds. This method takes advantages of mild condition, simple work-up, high yield as well as wide substrate s