Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Zhi-cheng Huang"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102072- (2023)
Paired SpCas9 nickases (SpCas9n) are an effective strategy to reduce off-target effect in genome editing. However, this approach is not efficient with 3′-overhanging ends, limiting its applications. In order to expand the utility of paired SpCas9n
Externí odkaz:
https://doaj.org/article/8c880b1b54f84caeabaf083b01abb9ed
Autor:
Si-Cheng Liu, Yi-Li Feng, Xiu-Na Sun, Ruo-Dan Chen, Qian Liu, Jing-Jing Xiao, Jin-Na Zhang, Zhi-Cheng Huang, Ji-Feng Xiang, Guo-Qiao Chen, Yi Yang, Chao Lou, Hao-Dan Li, Zhen Cai, Shi-Ming Xu, Hui Lin, An-Yong Xie
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Due to post-cleavage residence of the Cas9-sgRNA complex at its target, Cas9-induced DNA double-strand breaks (DSBs) have to be exposed to engage DSB repair pathways. Target interaction of Cas9-sgRNA determines its target binding
Externí odkaz:
https://doaj.org/article/3baeafdd016e47d9820a0acff3a8a5a0
Autor:
Yi-Li Feng, Qian Liu, Ruo-Dan Chen, Si-Cheng Liu, Zhi-Cheng Huang, Kun-Ming Liu, Xiao-Ying Yang, An-Yong Xie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
It remains unclear how BRCA1-associated mutational sigantures are generated in cancer. Here, the authors develop nCas9-based approaches to uncover that aberrant repair of one-ended DSBs converted from DNA nicks by replication, not that of two-ended D
Externí odkaz:
https://doaj.org/article/d810812f909745a59edd229ffcf2ef63
Publikováno v:
Drones, Vol 6, Iss 12, p 401 (2022)
Bottle marine debris (BMD) remains one of the most pressing global issues. This study proposes a detection method for BMD using unmanned aerial vehicles (UAV) and machine learning techniques to enhance the efficiency of marine debris studies. The UAV
Externí odkaz:
https://doaj.org/article/b57558d299e24fdc952520a80f84a940
Publikováno v:
AIP Advances, Vol 7, Iss 12, Pp 125316-125316-14 (2017)
An air-coupled ultrasonic method, focusing on the problem that weak bonding interface is difficult to accurately measure using conventional nondestructive testing technique, is proposed to evaluate the bond integrity. Based on the spring model and th
Externí odkaz:
https://doaj.org/article/44dc1c25244e49bb9ca957774b56eaa7
Publikováno v:
Materials, Vol 11, Iss 2, p 310 (2018)
The ultrasonic transmission spectrum in a double-layered bonded structure is related closely to its interfacial stiffness. Consequently, researching the regularity of the transmission spectrum is of significant interest in evaluating the integrity of
Externí odkaz:
https://doaj.org/article/8b4bfbf390cd443eb7b2b4e8c03325cb
Autor:
Zhi-Cheng Huang, 黃智呈
104
In recent years, some methods have been presented based on interval-valued intuitionistic fuzzy sets for multiattribute decision making. In this thesis, we propose a new multiattribute decision making method based on interval-valued intuitio
In recent years, some methods have been presented based on interval-valued intuitionistic fuzzy sets for multiattribute decision making. In this thesis, we propose a new multiattribute decision making method based on interval-valued intuitio
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/52333321606816666877
Autor:
Zhi-Cheng Huang, 黃志誠
101
Human-machine interface is the media of information exchange, communication and interaction between electromechanical system and user, and most of the way through still-contact devices such as a keyboard or mouse for command input. To make t
Human-machine interface is the media of information exchange, communication and interaction between electromechanical system and user, and most of the way through still-contact devices such as a keyboard or mouse for command input. To make t
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/25902762415325625231
Autor:
ZHI-CHENG HUANG, 黃致誠
99
There are many vibration reduction techniques that have been studied for reducing vibration of simulated CD-ROM drive under high speed of rotation and read-write action of reader. Due to good vibration absorption, low cost and easy installati
There are many vibration reduction techniques that have been studied for reducing vibration of simulated CD-ROM drive under high speed of rotation and read-write action of reader. Due to good vibration absorption, low cost and easy installati
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/88962858868475244932
Autor:
Zhi-Cheng Huang, 黃志誠
92
The objectives of this study are to investigate the effects of the berm geometries and wave conditions on the accumulative transport rate and the evolution process of submerged berms. The experiments were conducted in a wave flume under a con
The objectives of this study are to investigate the effects of the berm geometries and wave conditions on the accumulative transport rate and the evolution process of submerged berms. The experiments were conducted in a wave flume under a con
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/at27c8