Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Zhi-chao Qu"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 311:C652-C662
Vitamin C, or ascorbic acid, both tightens the endothelial permeability barrier in basal cells and also prevents barrier leak induced by inflammatory agents. Barrier tightening by ascorbate in basal endothelial cells requires nitric oxide derived fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc4feeffdde1b227cd5aa996c1b848d
https://doi.org/10.1152/ajpcell.00076.2016
https://doi.org/10.1152/ajpcell.00076.2016
Autor:
James M. May, Zhi-chao Qu
Publikováno v:
BioFactors. 41:330-338
Microvascular pericytes take up ascorbic acid on the ascorbate transporter SVCT2. Intracellular ascorbate then protects the cells against apoptosis induced by culture at diabetic glucose concentrations. To investigate whether pericytes might also pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b168f2c6e0f666dd7bf5159e62acbc48
https://doi.org/10.1002/biof.1227
https://doi.org/10.1002/biof.1227
Publikováno v:
Biochemical and Biophysical Research Communications. 458:262-267
Intracellular vitamin C, or ascorbic acid, has been shown to prevent the apoptosis of cultured vascular pericytes under simulated diabetic conditions. We sought to determine the mechanism by which ascorbate is transported into pericytes prior to exer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5302f7ea21a6c67d51314e5532fcc2d0
https://doi.org/10.1016/j.bbrc.2015.01.096
https://doi.org/10.1016/j.bbrc.2015.01.096
Autor:
May, James M.1, Zhi-Chao Qu1
Publikováno v:
Biofactors. 2004, Vol. 20 Issue 4, p199-211. 13p. 1 Diagram, 6 Graphs.
Publikováno v:
Brain Research Bulletin. 90:35-42
Ascorbic acid enhances synthesis of norepinephrine from dopamine in adrenal chromaffin cells by serving as a co-factor for chromaffin granule dopamine β-hydroxylase (DβH). However, there is controversy regarding in situ kinetics of the ascorbate ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100ecb8de4099e30dabee5c9fd35be58
https://doi.org/10.1016/j.brainresbull.2012.09.009
https://doi.org/10.1016/j.brainresbull.2012.09.009
Autor:
James M. May, Zhi-chao Qu
Publikováno v:
Biochemical and Biophysical Research Communications. 404:701-705
Vitamin C, or ascorbic acid, decreases paracellular endothelial permeability in a process that requires rearrangement of the actin cytoskeleton. To define the proximal mechanism of this effect, we tested whether it might involve enhanced generation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c054187782434b298b05ce7673064f
https://doi.org/10.1016/j.bbrc.2010.12.046
https://doi.org/10.1016/j.bbrc.2010.12.046
Ascorbic acid prevents increased endothelial permeability caused by oxidized low density lipoprotein
Autor:
James M. May, Zhi-chao Qu
Publikováno v:
Free Radical Research. 44:1359-1368
Mildly oxidized low density lipoprotein (mLDL) acutely increases the permeability of the vascular endothelium to molecules that would not otherwise cross the barrier. This study has shown that ascorbic acid tightens the permeability barrier in the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01cc594d3f327db119080abce2700f6
https://doi.org/10.3109/10715762.2010.508496
https://doi.org/10.3109/10715762.2010.508496
Autor:
Zhi-chao Qu, James M. May
Publikováno v:
Archives of Biochemistry and Biophysics. 500:162-168
Ascorbic acid improves endothelial barrier function by decreasing the permeability of endothelial cells cultured on semi-porous membrane filters. This decrease was not due to enhanced collagen synthesis and was mimicked by the collagen synthesis inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9655230b27973b293f5f0596fc54fb
https://doi.org/10.1016/j.abb.2010.05.022
https://doi.org/10.1016/j.abb.2010.05.022
Publikováno v:
Clinical Biochemistry. 40:1135-1142
Objectives: The reducing capacity of erythrocytes has been used clinically as to estimate resistance to oxidant stress. In this work we targeted the antioxidant capacity of pyridine nucleotide disulfide reductases of these cells by measuring their ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::331c9df90a848a1b0f4bc7e839665596
https://doi.org/10.1016/j.clinbiochem.2007.06.009
https://doi.org/10.1016/j.clinbiochem.2007.06.009
Publikováno v:
Biochemical and Biophysical Research Communications. 360:295-298
Erythrocytes have the same intracellular concentration of ascorbate as plasma, which is much lower than that of nucleated cells. To determine why erythrocytes are unable to concentrate ascorbate, we tested for the presence of ascorbate transporters i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d55ac9fe66a4d3aa63cbc6ae22cdf91
https://doi.org/10.1016/j.bbrc.2007.06.072
https://doi.org/10.1016/j.bbrc.2007.06.072