Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zhi-Yang Tsun"'
Autor:
Daniel, Maeng, Zhi-Yang, Tsun, Eric, Lesch, David B, Jacobowitz, Robert L, Strawderman, Donald K, Harrington, Yue, Li, Robert L, Weisman, J Steven, Lamberti
Publikováno v:
Psychiatric Services. 74:358-364
In this study, the authors assessed return on investment (ROI) associated with a forensic assertive community treatment (FACT) program.A retrospective secondary data analysis of a randomized controlled trial comprising 70 legal-involved patients with
Autor:
Adam C. Simning, Zhi-Yang Tsun, Nirav R. Shah, Elizabeth J. Santos, Lara Press-Ellingham, Michael J. Hasselberg
Publikováno v:
NEJM Catalyst. 3
Autor:
Shuyu Wang1,2,3,4, Zhi-Yang Tsun1,2,3,4, Wolfson, Rachel L.1,2,3,4, Kuang Shen1,2,3,4, Wyant, Gregory A.1,2,3,4, Plovanich, Molly E.5, Yuan, Elizabeth D.1,2,3,4, Jones, Tony D.1,2,3,4, Chantranupong, Lynne1,2,3,4, Comb, William1,2,3,4, Tim Wang1,2,3,4, Bar-Peled, Liron1,2,3,4, Zoncu, Roberto1,2,3,4, Straub, Christoph6, Choah Kim1,2,3,4, Jiwon Park1,2,3,4, Sabatini, Bernardo L.6, Sabatini, David M.1,2,3,4 sabatini@wi.mit.edu
Publikováno v:
Science. 1/9/2015, Vol. 347 Issue 6218, p188-194. 7p.
Autor:
Roberto Zoncu, David M. Sabatini, William C. Comb, Bernardo L. Sabatini, Lynne Chantranupong, Rachel L. Wolfson, Molly Plovanich, Zhi-Yang Tsun, Shuyu Wang, Choah Kim, Christoph Straub, Kuang Shen, Tony D. Jones, Liron Bar-Peled, Timothy C. Wang, Gregory A. Wyant, Jiwon Park, Elizabeth D. Yuan
Publikováno v:
Science. 347:188-194
Sensing amino acids at the lysosome The mTORC1 protein kinase is a complex of proteins that functions to regulate growth and metabolism. Activity of mTORC1 is sensitive to the abundance of amino acids, but how the sensing of amino acids is coupled to
Autor:
Choah Kim, Liron Bar-Peled, Timothy C. Wang, Eric Spooner, Lynne Chantranupong, David M. Sabatini, Zhi-Yang Tsun, Roberto Zoncu
Publikováno v:
PMC
The mTORC1 kinase is a master growth regulator that senses numerous environmental cues, including amino acids. The Rag GTPases interact with mTORC1 and signal amino acid sufficiency by promoting the translocation of mTORC1 to the lysosomal surface, i
Autor:
Weinian Shou, Ching Pin Chang, Hanying Chen, Ching Shang, Jiang Wu, Zhi-Yang Tsun, J. Henri Bayle, Nathan V. Lee, M. Luisa Iruela-Arispe, Kryn Stankunas, Calvin T. Hang
Publikováno v:
Developmental Cell. 14:298-311
SummaryDeveloping myocardial cells respond to signals from the endocardial layer to form a network of trabeculae that characterize the ventricles of the vertebrate heart. Abnormal myocardial trabeculation results in specific cardiomyopathies in human
Publikováno v:
Biochemical Journal. 402:279-290
The glucose transporter GLUT4 and the aminopeptidase IRAP (insulin-responsive aminopeptidase) are the major cargo proteins of GSVs (GLUT4 storage vesicles) in adipocytes and myocytes. In the basal state, most GSVs are sequestered in perinuclear and o
Autor:
Zhi-Yang Tsun, Richard Possemato
Publikováno v:
Seminars in celldevelopmental biology. 43
Amino acids have a dual role in cellular metabolism, as they are both the building blocks for protein synthesis and intermediate metabolites which fuel other biosynthetic reactions. Recent work has demonstrated that deregulation of both arms of amino
Autor:
Shuyu, Wang, Zhi-Yang, Tsun, Rachel L, Wolfson, Kuang, Shen, Gregory A, Wyant, Molly E, Plovanich, Elizabeth D, Yuan, Tony D, Jones, Lynne, Chantranupong, William, Comb, Tim, Wang, Liron, Bar-Peled, Roberto, Zoncu, Christoph, Straub, Choah, Kim, Jiwon, Park, Bernardo L, Sabatini, David M, Sabatini
The mechanistic target of rapamycin complex 1 (mTORC1) protein kinase is a master growth regulator that responds to multiple environmental cues. Amino acids stimulate, in a Rag-, Ragulator-, and vacuolar adenosine triphosphatase-dependent fashion, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::25785da592e12cd032c741839e18239e
https://europepmc.org/articles/PMC4295826/
https://europepmc.org/articles/PMC4295826/
Autor:
Zhi-Yang Tsun, Tobias N. Meyer, Catherine Meyer Schwesinger, Ray M. Lee, Tsung-Yin J. Yeh, Nai-Wen Chi
Publikováno v:
Biochemical Journal. 399:415-425
PARsylation [poly(ADP-ribosyl)ation] of proteins is implicated in the regulation of diverse physiological processes. Tankyrase is a molecular scaffold with this catalytic activity and has been proposed as a regulator of vesicular trafficking on the b