Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zhi-Xuan Xia"'
Regulation of anxiety-like behaviors by S-palmitoylation and S-nitrosylation in basolateral amygdala
Autor:
Zu-Cheng Shen, Jian-Min Liu, Jie-Yan Zheng, Meng-Die Li, Dan Tian, Yue Pan, Wu-Cheng Tao, Shuang-Qi Gao, Zhi-Xuan Xia
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115859- (2023)
Protein posttranslational modification regulates synaptic protein stability, sorting and trafficking, and is involved in emotional disorders. Yet the molecular mechanisms regulating emotional disorders remain unelucidated. Here we report unknown role
Externí odkaz:
https://doaj.org/article/3250b1e96d76432596d199b0ae829e09
Autor:
Meng-Die Li, Lu Wang, Yu-Qi Zheng, Dan-Hong Huang, Zhi-Xuan Xia, Jian-Min Liu, Dan Tian, Hui OuYang, Zi-Hao Wang, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Yue-Ling Zhao, Jia-An Liu, Zu-Cheng Shen
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107561- (2023)
Summary: Palmitoyl acyltransferases (PATs) have been suggested to be involved in learning and memory. However, the underlying mechanisms have not yet been fully elucidated. Here, we found that the activity of DHHC2 was upregulated in the hippocampus
Externí odkaz:
https://doaj.org/article/b9a49af21c67450d8224e6de117c7de0
Autor:
Shao-Qi Zhang, Zhi-Xuan Xia, Qiao Deng, Ping-Fen Yang, Li-Hong Long, Fang Wang, Jian-Guo Chen
Publikováno v:
Neurobiology of Stress, Vol 18, Iss , Pp 100453- (2022)
Repeated vagus nerve stimulation (rVNS) exerts anxiolytic effect by activation of noradrenergic pathway. Centrolateral amygdala (CeL), a lateral subdivision of central amygdala, receives noradrenergic inputs, and its neuronal activity is positively c
Externí odkaz:
https://doaj.org/article/3265ca23a2a24660b3e06b99837eaf86
Autor:
Yu-Fei Luo, Xiao-Xia Ye, Ying-Zhao Fang, Meng-Die Li, Zhi-Xuan Xia, Jian-Min Liu, Xiao-Shan Lin, Zhen Huang, Xiao-Qian Zhu, Jun-Jie Huang, Dong-Lin Tan, Yu-Fei Zhang, Hai-Ping Liu, Jun Zhou, Zu-Cheng Shen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: The mechanistic target of rapamycin complex 1 (mTORC1) signaling has served as a promising target for therapeutic intervention of major depressive disorder (MDD), but the mTORC1 signaling underlying MDD has not been well elucidated. In th
Externí odkaz:
https://doaj.org/article/3aadb14777de4859af08bac8ae503cc2
Autor:
Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zhou
Publikováno v:
J Neurosci
Palmitoylation may be relevant to the processes of learning and memory, and even disorders, such as post-traumatic stress disorder and aging-related cognitive decline. However, underlying mechanisms of palmitoylation in these processes remain unclear
Autor:
Meng-Die Li, Dan-Hong Huang, Yu-Qi Zheng, Dan Tian, Hui OuYang, Ke-Xin Song, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Jun-Jie Huang, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Jian-Min Liu, Zhi-Xuan Xia, Zu-Cheng Shen
Background A-kinase anchoring protein 79/150 (AKAP150) has been suggested to be involved in learning and memory, and synaptic plasticity in the hippocampus is closely associated with memory. However, its effect and underlying mechanisms have not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b3b8f30e282818167b88a7806bdde9
https://doi.org/10.21203/rs.3.rs-2180782/v1
https://doi.org/10.21203/rs.3.rs-2180782/v1
Autor:
Shao-Qi Zhang, Zhi-Xuan Xia, Qiao Deng, Ping-Fen Yang, Li-Hong Long, Fang Wang, Jian-Guo Chen
Publikováno v:
Neurobiology of stress. 18
Repeated vagus nerve stimulation (rVNS) exerts anxiolytic effect by activation of noradrenergic pathway. Centrolateral amygdala (CeL), a lateral subdivision of central amygdala, receives noradrenergic inputs, and its neuronal activity is positively c
Autor:
Hong-Ji Yao, Zhao-Yi Xue, Rui-Qi Wang, Cheng-Zuo Jiang, Jing-Yan Xiong, Zhi-Xuan Xia, Qiang Liu, Qi-Bing Li, Yong Zhang
Publikováno v:
Journal of Hainan Medical University; May2022, Vol. 28 Issue 9, p14-21, 8p
Autor:
Hui-Ling Zheng, Xia-Ping Yao, Wen-Hui Liu, Zhi-Xuan Xia, Jia-Jing Lu, Jian-Guo Chen, Li-Hong Long, Tai-Lei Nie, Peng-Fei Wu, Fang Wang, Zu-Cheng Shen, Shao-Qi Zhang, Qiao Deng, Shuang-Qi Gao, Zhuang-Li Hu
Publikováno v:
Biological psychiatry. 85(3)
Background Benzodiazepines (BZDs) have been used to treat anxiety disorders for more than five decades as the allosteric modulator of the gamma-aminobutyric acid A receptor (GABAAR). Little is known about other mechanisms of BZDs. Here, we describe h
Autor:
Kuan Li, Jian-Guo Chen, Shuang-Qi Gao, Jie-Ting Zhang, Fang Wang, Zhi-Xuan Xia, Hong-Sheng Chen, Hai Zhang
Publikováno v:
Brain structurefunction. 223(5)
Hypofunction of the serotonergic (5-HT) system has close relationship with the symptoms in major depressive disorders (MDD), however, the underlying neural circuitry mechanisms are not fully understood. Lateral habenula (LHb) plays a crucial role in