Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Zhi-Qin Jiang"'
Autor:
Isidore Rigoutsos, Sang Kil Lee, Su Youn Nam, Simone Anfossi, Barbara Pasculli, Martin Pichler, Yi Jing, Cristian Rodriguez-Aguayo, Aristeidis G. Telonis, Simona Rossi, Cristina Ivan, Tina Catela Ivkovic, Linda Fabris, Peter M. Clark, Hui Ling, Masayoshi Shimizu, Roxana S. Redis, Maitri Y. Shah, Xinna Zhang, Yoshinaga Okugawa, Eun Jung Jung, Aristotelis Tsirigos, Li Huang, Jana Ferdin, Roberta Gafà, Riccardo Spizzo, Milena S. Nicoloso, Anurag N. Paranjape, Maryam Shariati, Aida Tiron, Jen Jen Yeh, Raul Teruel-Montoya, Lianchun Xiao, Sonia A. Melo, David Menter, Zhi-Qin Jiang, Elsa R. Flores, Massimo Negrini, Ajay Goel, Menashe Bar-Eli, Sendurai A. Mani, Chang Gong Liu, Gabriel Lopez-Berestein, Ioana Berindan-Neagoe, Manel Esteller, Scott Kopetz, Giovanni Lanza, George A. Calin
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Non-coding RNAs have been drawing increasing attention in recent years as functional data suggest that they play important roles in key cellular processes. N-BLR is a primate-specific long non-coding RNA that modulates the epithel
Externí odkaz:
https://doaj.org/article/1e8d188da0bf4c3faa5d2b002a7f8760
Autor:
Christopher H Lieu, Hai Tran, Zhi-Qin Jiang, Muling Mao, Michael J Overman, E Lin, Cathy Eng, Jeffrey Morris, Lee Ellis, John V Heymach, Scott Kopetz
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77117 (2013)
BACKGROUND:Circulating angiogenic factors are altered in patients with mCRC receiving bevacizumab. Evaluation of alterations in levels of VEGF ligands may provide insights into possible resistance mechanisms. METHODS:PlGF, VEGF-A, VEGF-C, and VEGF-D
Externí odkaz:
https://doaj.org/article/b43c498c64aa4902a269a0b899dfd144
Autor:
Michael J Overman, Jiexin Zhang, Scott Kopetz, Michael Davies, Zhi-Qin Jiang, Katherine Stemke-Hale, Petra Rümmele, Christian Pilarsky, Robert Grützmann, Stanley Hamilton, Rosa Hwang, James L Abbruzzese, Gauri Varadhachary, Bradley Broom, Huamin Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65144 (2013)
Adenocarcinomas of the ampulla of Vater are classified as biliary cancers, though the exact epithelium of origin for these cancers is not known. We sought to molecularly classify ampullary adenocarcinomas in comparison to known adenocarcinomas of the
Externí odkaz:
https://doaj.org/article/f624befd01aa4392a8481959a7844d88
Autor:
Michael J. Overman, Jiexin Zhang, Scott Kopetz, Michael Davies, Zhi-Qin Jiang, Katherine Stemke-Hale, Petra Rümmele, Christian Pilarsky, Robert Grützmann, Stanley Hamilton, Rosa Hwang, James L. Abbruzzese, Gauri Varadhachary, Bradley Broom, Huamin Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/b8e80e1bf74142dcb1d16d6632a47c31
Autor:
Scott Kopetz, Garth Powis, Michael J. Overman, Jeffrey Morris, Bradley M. Broom, Mingshan Cheng, Susan Airhart, Feng Tian, Christopher Bristow, Bahar Salimian Rizi, Alexey V. Sorokin, Ji Wu, Shanequa Manuel, Maria P. Morelli, Andreas Varkaris, David G. Menter, Zhi-Qin Jiang, Kanwal Raghav, Anastasia Katsiampoura
Association between surgical specimen size and rate of PDX establishment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1a3561b3894370a65e992a0deea967
https://doi.org/10.1158/1535-7163.22503978.v1
https://doi.org/10.1158/1535-7163.22503978.v1
Autor:
Scott Kopetz, Garth Powis, Michael J. Overman, Jeffrey Morris, Bradley M. Broom, Mingshan Cheng, Susan Airhart, Feng Tian, Christopher Bristow, Bahar Salimian Rizi, Alexey V. Sorokin, Ji Wu, Shanequa Manuel, Maria P. Morelli, Andreas Varkaris, David G. Menter, Zhi-Qin Jiang, Kanwal Raghav, Anastasia Katsiampoura
Hematoxylin and eosin staining showing conformity of grade between patient sample and respective established xenografts from both primary and metastatic sites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2bb06082f7ca75c4469315e54779cb
https://doi.org/10.1158/1535-7163.22503981
https://doi.org/10.1158/1535-7163.22503981
Autor:
Scott Kopetz, Garth Powis, Michael J. Overman, Jeffrey Morris, Bradley M. Broom, Mingshan Cheng, Susan Airhart, Feng Tian, Christopher Bristow, Bahar Salimian Rizi, Alexey V. Sorokin, Ji Wu, Shanequa Manuel, Maria P. Morelli, Andreas Varkaris, David G. Menter, Zhi-Qin Jiang, Kanwal Raghav, Anastasia Katsiampoura
Developing realistic preclinical models using clinical samples that mirror complex tumor biology and behavior are vital to advancing cancer research. While cell line cultures have been helpful in generating preclinical data, the genetic divergence be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbba52453d564e5c7b8979fa5a18c1e
https://doi.org/10.1158/1535-7163.c.6537579.v1
https://doi.org/10.1158/1535-7163.c.6537579.v1
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Purpose: Aberrant activation of the intracellular tyrosine kinase Src has been implicated as a mechanism of acquired chemotherapy resistance in metastatic colorectal cancer (mCRC). Here, the oral tyrosine kinase Src inhibitor, dasatinib, was investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493cba9094cd2e6c43821d133756c6a5
https://doi.org/10.1158/1078-0432.c.6526826
https://doi.org/10.1158/1078-0432.c.6526826
Autor:
Scott Kopetz, Marc Ychou, Safia El Messaoudi, Cynthia Sanchez, Michael J. Overman, Jonathan M. Loree, Christine Parseghian, Anastasia D. Katsiampoura, Zhi-Qin Jiang, Brice Pastor, Alain R. Thierry
Purpose: Liquid biopsies allow the tracking of clonal dynamics and detection of mutations during treatment.Experimental Design: We evaluated under blinded conditions the ability of cell-free DNA (cfDNA) to detect RAS/BRAF mutations in the plasma of 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bc00964f6d5b3c18327e32f627eabf
https://doi.org/10.1158/1078-0432.c.6525203.v1
https://doi.org/10.1158/1078-0432.c.6525203.v1
Autor:
Scott Kopetz, Michael A. Davies, Gary E. Gallick, Jayesh Desai, Garth Powis, Gordon B. Mills, Gideon Bollag, William G. Bornman, Xi M. Tang, Ignacio I. Wistuba, Zhi-Qin Jiang, Y.N. Vashisht Gopal, Farshid Dayyani, Robert Lemos, Chun C. Tsao, John M. Mariadason, Feng Tian, Muling Mao
PDF file - 39K, HT29 PLX4720 resistant clone was treated with EGFR siRNA for 48 h, and then treated with 1�M PLX4720 for further two weeks. EGFR knockdown reduced sensitivity to PLX4720 by numbers of formed colonies (# P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc22a97db08c50678f13fa79f95abaf
https://doi.org/10.1158/1078-0432.22445823.v1
https://doi.org/10.1158/1078-0432.22445823.v1