Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Zhi-Qiang Xiao"'
Autor:
Wei Huang, Qi Wen, Ting Zeng, Di Wu, Li Yuan, Wei Zhu, Zheng-Zheng Yu, Yun-Ya Liu, Ding Xiao, Shan-Shan Lu, Hong Yi, Xue-Ping Feng, Jie-Ya Qiu, Jian-Hua Zhou, Wei Zhuang, Zhi-Qiang Xiao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background Immune checkpoint inhibitors (ICIs) therapy targeting programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) shows promising clinical benefits. However, the relatively low response rate highlights the need to develop an alte
Externí odkaz:
https://doaj.org/article/ebcb9eb3cca34f51ae357592c47255ad
Autor:
Zhen-Qi Qin, Qi-Guang Li, Hong Yi, Shan-Shan Lu, Wei Huang, Zhuo-Xian Rong, Yao-Yun Tang, Zhi-Qiang Xiao
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. However, the role of this mutation in the pathogenesis of NPC remains unclear. I
Externí odkaz:
https://doaj.org/article/958b09b156664dd9ac87c6f0fc1ef7a2
Autor:
Zhaozhong Li, Taofeek K. Owonikoko, Shi-Yong Sun, Suresh S. Ramalingam, Paul W. Doetsch, Zhi-Qiang Xiao, Fadlo R. Khuri, Walter J. Curran, Xingming Deng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1190-1202 (2012)
c-Myc is a transcriptional factor that functions as a central regulator of cell growth, proliferation, and apoptosis. Overexpression of c-Myc also enhances DNA double-strand breaks (DSBs), genetic instability, and tumorigenesis. However, the mechanis
Externí odkaz:
https://doaj.org/article/5e14fa5e306c4a8b95fd0035a837401f
Autor:
Xin-Hui Li, Jia-Quan Qu, Hong Yi, Peng-Fei Zhang, Hong-Mei Yi, Xun-Xun Wan, Qiu-Yan He, Xu Ye, Li Yuan, Jing-Feng Zhu, Jiao-Yang Li, Zhi-Qiang Xiao
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87767 (2014)
BACKGROUND:The purpose of this study was to identify miRNAs and genes involved in nasopharyngeal carcinoma (NPC) radioresistance, and explore the underlying mechanisms in the development of radioresistance. METHODS:We used microarrays to compare the
Externí odkaz:
https://doaj.org/article/63c9aa244b0640f980f705812784ba24
Autor:
Gu-Qing Zeng, Hong Yi, Peng-Fei Zhang, Xin-Hui Li, Rong Hu, Mao-Yu Li, Cui Li, Jia-Quan Qu, Xingming Deng, Zhi-Qiang Xiao
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71865 (2013)
BACKGROUND: Our quantitative proteomic study showed that selenium-binding protein 1 (SELENBP1) was progressively decreased in human bronchial epithelial carcinogenic process. However, there is little information on expression and function of SELENBP1
Externí odkaz:
https://doaj.org/article/12115ebb6f3f47908b734e8a40cec868
Autor:
Zhi-Qiang Xiao, Shan-Shan Lu, Qiu-Yan He, Juan Feng, Yuan-Yuan Wang, Jiao-Yang Li, Li Yuan, Ta Xiao, Li-Na Li, Hong Yi, Jin-Feng Zhu, Xu Ye, Hong-Mei Yi, Jia-Quan Qu
Microarray-based detection of differentially expressed miRNAs anticorrelated with mRNA expression in the CNE2-IR and CNE2 NPC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8aca763b177529cd08232f58af54bb
https://doi.org/10.1158/1535-7163.22506933
https://doi.org/10.1158/1535-7163.22506933
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 218K, Ionizing radiation (IR) induces activation of the JAK2/STAT3/Bcl2/Bcl-XL survival signaling pathway in various human lung cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05beb452e95508abedf5c4f12d765674
https://doi.org/10.1158/1535-7163.22500037.v1
https://doi.org/10.1158/1535-7163.22500037.v1
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
A major challenge affecting the outcomes of patients with lung cancer is the development of acquired radioresistance. However, the mechanisms underlying the development of resistance to therapy are not fully understood. Here, we discovered that ioniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2336cd391f39fe839413d713044a7d
https://doi.org/10.1158/1535-7163.c.6536332.v1
https://doi.org/10.1158/1535-7163.c.6536332.v1
Autor:
Zhi-Qiang Xiao, Shan-Shan Lu, Qiu-Yan He, Juan Feng, Yuan-Yuan Wang, Jiao-Yang Li, Li Yuan, Ta Xiao, Li-Na Li, Hong Yi, Jin-Feng Zhu, Xu Ye, Hong-Mei Yi, Jia-Quan Qu
Correlation analyses based on IHC scores and qRT-PCR 2-DDCt values (Spearman rank correlation test). The correlations shown include those between IL-8 and phospho-AKT (A), IL-8 and miR-203(B) and phospho-AKT and miR-203(C).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008b834fe2d73e402bd2774b621534f0
https://doi.org/10.1158/1535-7163.22506942.v1
https://doi.org/10.1158/1535-7163.22506942.v1
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 74K, Niclosamide (Niclo) reduces STAT3 nuclear localization in radioresistant human lung cancer A549-IRR cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25581dbd94ec7ed360fe2756f6affe6c
https://doi.org/10.1158/1535-7163.22500034
https://doi.org/10.1158/1535-7163.22500034