Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Zhi-Ping Feng"'
Autor:
Chelisa Cardinez, Yuwei Hao, Kristy Kwong, Ainsley R. Davies, Morgan B. Downes, Nadia A. Roberts, Jason D. Price, Raquel A. Hernandez, Jessica Lovell, Rochna Chand, Zhi-Ping Feng, Anselm Enders, Carola G. Vinuesa, Bahar Miraghazadeh, Matthew C. Cook
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Loss-of-function mutations have provided crucial insights into the immunoregulatory actions of Foxp3+ regulatory T cells (Tregs). By contrast, we know very little about the consequences of defects that amplify aspects of Treg function or dif
Externí odkaz:
https://doaj.org/article/db07c536c7a44f49859f6963437bbf1a
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Total joint replacement for osteoarthritis is one of the most successful surgical procedures in modern medicine. However, aseptic loosening continues to be a leading cause of revision arthroplasty. The diagnosis of aseptic looseni
Externí odkaz:
https://doaj.org/article/17e9d0ceef054c3187bb0c28907bf23e
Autor:
Andrew J. Kueh, Maria I. Bergamasco, Anna Quaglieri, Belinda Phipson, Connie S.N. Li-Wai-Suen, Ingrid M. Lönnstedt, Yifang Hu, Zhi-Ping Feng, Chris Woodruff, Rose E. May, Stephen Wilcox, Alexandra L. Garnham, Michael P. Snyder, Gordon K. Smyth, Terence P. Speed, Tim Thomas, Anne K. Voss
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111980- (2023)
Summary: In the conventional model of transcriptional activation, transcription factors bind to response elements and recruit co-factors, including histone acetyltransferases. Contrary to this model, we show that the histone acetyltransferase KAT7 (H
Externí odkaz:
https://doaj.org/article/4b0b1023c1f947b38cbb26ac1b1ba97c
Autor:
Joshua A. Chu-Tan, Adrian V. Cioanca, Zhi-Ping Feng, Yvette Wooff, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Abstract Background MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with ar
Externí odkaz:
https://doaj.org/article/e8092aeac0204c3e936b785d776b9dc5
Autor:
Cardinez, Chelisa, Yuwei Hao, Kwong, Kristy, Davies, Ainsley R., Downes, Morgan B., Roberts, Nadia A., Price, Jason D., Hernandez, Raquel A., Lovell, Jessica, Chand, Rochna, Zhi-Ping Feng, Enders, Anselm, Vinuesa, Carola G., Miraghazadeh, Bahar, Cook, Matthew C.
Publikováno v:
Nature Communications; 3/25/2024, Vol. 15 Issue 1, p1-17, 17p, 7 Graphs
Autor:
Yuwei Hao, Bahar Miraghazadeh, Rochna Chand, Ainsley R. Davies, Chelisa Cardinez, Kristy Kwong, Morgan B. Downes, Rebecca A. Sweet, Pablo F. Cañete, Lloyd J. D’Orsogna, David A. Fulcher, Sharon Choo, Desmond Yip, Geoffrey Peters, Sonia Yip, Matthew J. Witney, Maxim Nekrasov, Zhi-Ping Feng, David C. Tscharke, Carola G. Vinuesa, Matthew C. Cook
As chronic antigenic stimulation from infection and autoimmunity is a feature of primary antibody deficiency (PAD), analysis of affected patients could yield insights into T-cell differentiation and explain how environmental exposures modify clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03d8ab39340c736b2fb1f6f7c136661
https://www.repository.cam.ac.uk/handle/1810/353613
https://www.repository.cam.ac.uk/handle/1810/353613
Autor:
Matthew Cook, Yuwei Hao, Bahar Miraghazadeh, Rochna Chand, Ainsley Davies, Chelisa Cardinez, Kristy Kwong, Morgan Downes, Rebecca Sweet, Pablo Cañete, Lloyd D’Orsogna, David Fulcher, Sharon Choo, Desmond Yip, Geoffrey Peters, Sonia Yip, Matthew Witney, Maxim Nekrasov, Zhi-Ping Feng, David Tscharke, Carola Vinuesa
As chronic antigenic stimulation from infection and autoimmunity are features of primary antibody deficiency (PAD), analysis of affected patients could yield insights into T cell differentiation, and explain how environmental exposures modify clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d71b62dbc25bc815491be87f86d225
https://doi.org/10.21203/rs.3.rs-2377516/v1
https://doi.org/10.21203/rs.3.rs-2377516/v1
Autor:
Katherine M. Hannan, Priscilla Soo, Mei S. Wong, Justine K. Lee, Nadine Hein, Perlita Poh, Kira D. Wysoke, Tobias D. Williams, Christian Montellese, Lorey K. Smith, Sheren J. Al-Obaidi, Lorena Núñez-Villacís, Megan Pavy, Jin-Shu He, Kate M. Parsons, Karagh E. Loring, Tess Morrison, Jeannine Diesch, Gaetan Burgio, Rita Ferreira, Zhi-Ping Feng, Cathryn M. Gould, Piyush B. Madhamshettiwar, Johan Flygare, Thomas J. Gonda, Kaylene J. Simpson, Ulrike Kutay, Richard B. Pearson, Christoph Engel, Nicholas J. Watkins, Ross D. Hannan, Amee J. George
Publikováno v:
Cell reports. 41(5)
The nucleolar surveillance pathway monitors nucleolar integrity and responds to nucleolar stress by mediating binding of ribosomal proteins to MDM2, resulting in p53 accumulation. Inappropriate pathway activation is implicated in the pathogenesis of
Autor:
Hardip R. Patel, Matt Rutar, Riemke Aggio-Bruce, Joshua A Chu-Tan, Katherine M. Hannan, Jan Provis, Riccardo Natoli, Adrian V Cioanca, Yvette Wooff, Ulrike Schumann, Konstantin I. Panov, Zhi-Ping Feng
Publikováno v:
Chu-Tan, J A, Cioanca, A V, Feng, Z-P, Wooff, Y, Schumann, U, Aggio-Bruce, R, Patel, H, Rutar, M, Hannan, K, Panov, K, Provis, J & Natoli, R 2021, ' Functional microRNA targetome undergoes degeneration-induced shift in the retina ', Molecular Neurodegeneration, vol. 16, 60 . https://doi.org/10.1186/s13024-021-00478-9
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Background MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with argonaute 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a0146480e3a9b8a8d85822fac5f6f0
https://pure.qub.ac.uk/en/publications/functional-microrna-targetome-undergoes-degenerationinduced-shift-in-the-retina(7c57e170-c537-4fed-b1e8-accaa7c003cb).html
https://pure.qub.ac.uk/en/publications/functional-microrna-targetome-undergoes-degenerationinduced-shift-in-the-retina(7c57e170-c537-4fed-b1e8-accaa7c003cb).html
Autor:
Justine K. Lee, Ulrike Kutay, Sheren Al-Obaidi, Mei S. Wong, Priscilla Soo, Lorena Núñez-Villacís, Christian Montellese, Ross D. Hannan, Rita Ferreira, Kate M Parsons, Amee J George, Gaetan Burgio, Kaylene J. Simpson, Christoph Engel, Nicholas J. Watkins, Katherine M. Hannan, Tobias D. Williams, Johan Flygare, Cathryn M. Gould, Kira D. Wysoke, Maurits Evers, Zhi-Ping Feng, Thomas J. Gonda, Lorey K. Smith, Nadine Hein, Richard B. Pearson, Jeannine Diesch, Perlita Poh, Piyush B. Madhamshettiwar, Megan Pavy, Jin-Shu He
The nucleolar surveillance pathway (NSP) monitors nucleolar fidelity and responds to nucleolar stresses (i.e., inactivation of ribosome biogenesis) by mediating the inhibitory binding of ribosomal proteins (RPs) to mouse double minute 2 homolog (MDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f004f573c723ed975ca1ebf9c31b2e
https://doi.org/10.1101/2021.01.21.427535
https://doi.org/10.1101/2021.01.21.427535