Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Zhi-Peng Chen"'
Autor:
Yang Li, Zhi-Peng Chen, Da Xu, Liang Wang, Meng-Ting Cheng, Cong-Zhao Zhou, Yuxing Chen, Wen-Tao Hou
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Human ABC transporters ABCD1–3 are all localized on the peroxisomal membrane and participate in the β-oxidation of fatty acyl-CoAs, but they differ from each other in substrate specificity. The transport of branched-chain fatty acids from
Externí odkaz:
https://doaj.org/article/581cb282ce8144469826f749840ea3e7
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 9, Iss 7, Pp 920-923 (2024)
Exoristobia philippinensis (Hymenoptera: Encyrtidae) is a worldwide parasitic wasp. This work presents the mitochondrial genome (mitogenome) of E. philippinensis for the first time. The complete mitochondrial genome of E. philippinensis was sequenced
Externí odkaz:
https://doaj.org/article/7be26eb998324660aa465bd9e000bce4
Publikováno v:
Brain Research Bulletin, Vol 217, Iss , Pp 111079- (2024)
Generalized fear is a maladaptive behavior in which non-threatening stimuli elicit a fearful response. The ventral tegmental area (VTA) has been demonstrated to play important roles in fear response and fear memory generalization, but the precious ne
Externí odkaz:
https://doaj.org/article/a7456a0e06254a1e8e1d2b7ee0d38783
Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Bilirubin is mainly generated from the breakdown of heme when red blood cells reach the end of their lifespan. Accumulation of bilirubin in human body usually leads to various disorders, including jaundice and liver disease. Bilirubin is con
Externí odkaz:
https://doaj.org/article/57ee975539034a8db12af416e87e66ec
Autor:
Zhi-Peng Chen, Da Xu, Liang Wang, Yao-Xu Mao, Yang Li, Meng-Ting Cheng, Cong-Zhao Zhou, Wen-Tao Hou, Yuxing Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Human ABC transporter ABCD1 transports very long-chain fatty acids from cytosol to peroxisome for βoxidation, dysfunction of which causes the X-ALD. Here, the authors report three structures of ABCD1: the ligand-free, C22:0-CoA- and ATP-bound forms.
Externí odkaz:
https://doaj.org/article/ff6ddb758b6142058dea3373e013093d
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 5, Pp 479-485 (2022)
Abstract To exploit whether early continuous blood purification (CBP) inhibits the Toll‐like receptors 4 (TLR4) signaling pathway in the peripheral blood of patients with severe acute pancreatitis (SAP) and whether it affects the abundance of infla
Externí odkaz:
https://doaj.org/article/857c202f45c848c59ae1b3da161d0f14
Autor:
Da Xu, Yanyan Li, Fengrui Yang, Cai-Rong Sun, Jinheng Pan, Liang Wang, Zhi-Peng Chen, Shu-Cheng Fang, Xuebiao Yao, Wen-Tao Hou, Cong-Zhao Zhou, Yuxing Chen
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110298- (2022)
Summary: The reverse cholesterol transport pathway is responsible for the maintenance of human cholesterol homeostasis, an imbalance of which usually leads to atherosclerosis. As a key component of this pathway, the ATP-binding cassette transporter A
Externí odkaz:
https://doaj.org/article/d42abb04ff4644b19b7a1dae181abc9e
Autor:
Xiao-Lan Qian, Fang Zhou, Song Xu, Jian Jiang, Zhi-Peng Chen, Shao-Kai Wang, Yun Zuo, Chen Ni
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Colorectal cancer is one of the most common malignancies worldwide. Oxaliplatin is the first-line chemotherapeutic agent for the treatment of advanced colorectal cancer. However, acquired resistance to oxaliplatin limits its therapeutic efficacy, and
Externí odkaz:
https://doaj.org/article/f80ff8b43fee4a0190bece966f9e9034
Autor:
Li Chen, Wen-Tao Hou, Tao Fan, Banghui Liu, Ting Pan, Yu-Hui Li, Yong-Liang Jiang, Wen Wen, Zhi-Peng Chen, Linfeng Sun, Cong-Zhao Zhou, Yuxing Chen
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The wall teichoic acid (WTA) is a major cell wall component of Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), a common cause of fatal clinical infections in humans. Thus, the indispensable ABC transporter
Externí odkaz:
https://doaj.org/article/4b2950cd0d604edc9b2a00799d40839d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 3, Pp 1258-1272 (2017)
Background: This study aimed to explore the effects of microRNA-21-5p (miR-21-5p) on the radiation sensitivity of non-small cell lung cancer (NSCLC) and the involvement of human MutS homolog 2 (hMSH2) One hundred fourteen NSCLC patients at stage II o
Externí odkaz:
https://doaj.org/article/67c20762f6a744c4b183d57a899409cc