Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zhi-Hang Li"'
Autor:
Chen Yang, Hong-yong Su, Ning An, Hong-luan Wu, Xiao-yan Guo, Zhi-hang Li, Xiao-cui Chen, Shao-ping Zhu, Dan Wu, Hui-yuan Li, Qing-jun Pan, Dong Liang, Hua-feng Liu
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-13 (2022)
Abstract Hyperuricemia can induce acute and chronic kidney damage, but the pathological mechanism remains unclear. The potential role of AMP-activated protein kinase (AMPK) α2 in hyperuricemia-induced renal injury was investigated in this study. Acu
Externí odkaz:
https://doaj.org/article/89e2fbdb311c49228c49cbcb455fff9f
Autor:
Ning An, Chen Yang, Hong-Luan Wu, Yun Guo, Xi-Jie Huang, Tong-Sheng Huang, Zhi-Hong Wu, Jing Xue, Rui-Hong Chen, Zhi-Hang Li, Qing-Jun Pan, Hua-Feng Liu
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-15 (2022)
Abstract Background Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions. As a classical lysosomal inhibit
Externí odkaz:
https://doaj.org/article/faab48701f13457e91f347b486d0dfff
Publikováno v:
Kidney Diseases, Vol 7, Iss 4, Pp 254-267 (2021)
Background: Macroautophagy (autophagy) is a cellular recycling process involving the destruction of damaged organelles and proteins in intracellular lysosomes for efficient nutrient reuse. Summary: Impairment of the autophagy-lysosome pathway is tigh
Externí odkaz:
https://doaj.org/article/a78185367b4144e2ae67ffc300418f39
Autor:
Zhi-hang Li, Xiao-yan Guo, Xiao-ying Quan, Chen Yang, Ze-jian Liu, Hong-yong Su, Ning An, Hua-feng Liu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Podocytopathy is the most common feature of glomerular disorder characterized by podocyte injury- or dysfunction-induced excessive proteinuria, which ultimately develops into glomerulosclerosis and results in persistent loss of renal function. Due to
Externí odkaz:
https://doaj.org/article/964db3944f2b4644bfd7e1d49824524c
Autor:
Wei Jing Liu, Zhi-hang Li, Xiao-cui Chen, Xiao-lu Zhao, Zhen Zhong, Chen Yang, Hong-luan Wu, Ning An, Wei-yan Li, Hua-feng Liu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Dysregulation of autophagy-mediated podocyte homeostasis is proposed to play a role in idiopathic membranous nephropathy (IMN). In the present study, autophagic activity and lysosomal alterations were investigated in podocytes of IMN patient
Externí odkaz:
https://doaj.org/article/a4703e3cb1294dfa93c816cb50b75cf6
Publikováno v:
Kidney Dis (Basel)
Kidney Diseases, Vol 7, Iss 4, Pp 254-267 (2021)
Kidney Diseases, Vol 7, Iss 4, Pp 254-267 (2021)
Background: Macroautophagy (autophagy) is a cellular recycling process involving the destruction of damaged organelles and proteins in intracellular lysosomes for efficient nutrient reuse. Summary: Impairment of the autophagy-lysosome pathway is tigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246d66b993db0c1f95fa7c5331fe9de9
https://doi.org/10.1159/000515035
https://doi.org/10.1159/000515035
Autor:
Ning An, Chen Yang, Hong-Luan Wu, Yun Guo, Xi-Jie Huang, Tong-Sheng Huang, Zhi-Hong Wu, Jing Xue, Rui-Hong Chen, Zhi-Hang Li, Qing-Jun Pan, Hua-Feng Liu
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-15 (2022)
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-15 (2022)
Background Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions. As a classical lysosomal inhibitor, HCQ m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbe805fdd923d0e138b026abcc8ce06
https://pubmed.ncbi.nlm.nih.gov/34980245
https://pubmed.ncbi.nlm.nih.gov/34980245
Autor:
Huafeng Liu, Biao Wei, Xiao-Ru Huang, Xiao-Cui Chen, Hong-Luan Wu, Zhi-hang Li, Chen Yang, Lin Ye, Hui-Yao Lan, Kai-Peng Jing
Publikováno v:
Autophagy
Macroautophagy/autophagy dysregulation has been noted in diabetic nephropathy; however, the regulatory mechanisms controlling this process remain unclear. In this study, we showed that SMAD3 (SMAD family member 3), the key effector of TGFB (transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78ee020f24151a2206980824430bd6d
https://pubmed.ncbi.nlm.nih.gov/33043774
https://pubmed.ncbi.nlm.nih.gov/33043774
Autor:
Hong-yong Su, Hong-Luan Wu, Qingjun Pan, Chen Yang, Xiao-Cui Chen, Ning An, Kai-Peng Jing, Xiao-Yan Guo, Zhi-hang Li, Huafeng Liu
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND Cell cycle arrest and autophagy have been demonstrated to be involved in various transforming growth factor (TGF)-s-mediated phenotype alterations of tubular epithelial cells (TECs) and tubulointerstitial fibrosis. But the relationship bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a6b0492a0e60c4ce0fb03090b39ab5
https://pubmed.ncbi.nlm.nih.gov/32555132
https://pubmed.ncbi.nlm.nih.gov/32555132
Autor:
Hua-Feng Liu, Chen Yang, Zhen Zhong, Hong-Luan Wu, Xiao-cui Chen, Wei Jing Liu, Ning An, Xiao-lu Zhao, Zhi-hang Li, Wei-yan Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Scientific Reports
Scientific Reports
Dysregulation of autophagy-mediated podocyte homeostasis is proposed to play a role in idiopathic membranous nephropathy (IMN). In the present study, autophagic activity and lysosomal alterations were investigated in podocytes of IMN patients and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00d40a62e51c919e53423fdcb76c6d9
https://doaj.org/article/a4703e3cb1294dfa93c816cb50b75cf6
https://doaj.org/article/a4703e3cb1294dfa93c816cb50b75cf6