Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Zhi-Bin Zhao"'
Autor:
Hao-Xian Zhu, Shu-Han Yang, Cai-Yue Gao, Zhen-Hua Bian, Xiao-Min Chen, Rong-Rong Huang, Qian-Li Meng, Xin Li, Haosheng Jin, Koichi Tsuneyama, Ying Han, Liang Li, Zhi-Bin Zhao, M. Eric Gershwin, Zhe-Xiong Lian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Primary biliary cholangitis (PBC) is a cholestatic autoimmune liver disease characterized by autoreactive T cell response against intrahepatic small bile ducts. Here, we use Il12b-/-Il2ra-/- mice (DKO mice) as a model of autoimmune cholangit
Externí odkaz:
https://doaj.org/article/a3208583c2fb4b3fbee865627da0c7c2
Autor:
Min Ma, Liang Li, Shu-Han Yang, Chuan Huang, Weitao Zhuang, Shujie Huang, Xin Xia, Yong Tang, Zijun Li, Zhi-Bin Zhao, Qingyun Chen, Guibin Qiao, Zhe-Xiong Lian
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTRegulatory T (Treg) cells are critical in shaping an immunosuppressive microenvironment to favor tumor progression and resistance to therapies. However, the heterogeneity and function of Treg cells in esophageal squamous cell carcinoma (ESCC)
Externí odkaz:
https://doaj.org/article/f5ed722987764aa5a7ce1a11d994c17c
Publikováno v:
Medicine Advances, Vol 1, Iss 2, Pp 97-114 (2023)
Abstract Autoimmune liver diseases (ALDs) are chronic inflammatory hepatobiliary diseases in which the autoimmune responses directed against liver tissue result in inflammation and tissue damage. There are several types of ALDs, including autoimmune
Externí odkaz:
https://doaj.org/article/2780f1a59ad043179553961b0d514f47
Autor:
Fei Wang, Chuan Huang, Jie Long, Zhi-Bin Zhao, Hai-Qing Ma, Xue-Qing Yao, Liang Li, Zhe-Xiong Lian
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The Notch signaling mutation is associated with enhanced anti-tumor immune response in colorectal cancer (CRC). In this study, we aim to investigate the underlying mechanism and the predictive potential of Notch signaling mutation
Externí odkaz:
https://doaj.org/article/d5c2699f83534ef2ab5a785254e98486
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Finding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly use non-direct associations, such as the Pearson correlation coefficient, and focus on the
Externí odkaz:
https://doaj.org/article/6fb76e2382c04aa0be5b4fe3dff0a666
Autor:
Ren-Dong Hu, Wen Zhang, Liang Li, Zu-Qi Zuo, Min Ma, Jin-Fen Ma, Ting-Ting Yin, Cai-Yue Gao, Shu-Han Yang, Zhi-Bin Zhao, Zi-Jun Li, Gui-Bin Qiao, Zhe-Xiong Lian, Kun Qu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Activation of adipose tissue macrophages (ATMs) contributes to chronic inflammation and insulin resistance in obesity. However, the transcriptional regulatory machinery involved in ATM activation during the development of obesity is not full
Externí odkaz:
https://doaj.org/article/ad58d1f293f74a799216e28a046493be
Autor:
Wanshan Du, Cai-Yue Gao, Xing You, Liang Li, Zhi-Bin Zhao, Mengting Fang, Zhiming Ye, Meijun Si, Zhe-Xiong Lian, Xueqing Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B cells under the regulation of CD4+T cells. However, the alterations of specific CD4+T cell subs
Externí odkaz:
https://doaj.org/article/6f0c37540c0945dc8283aa4b81456e87
Autor:
Xiao-Long Jiang, Pan-Yue Luo, Yan-Ying Zhou, Zhi-Hui Luo, Yue-Jun Hao, Ming-Zhi Fan, Xiao-Han Wu, Hao Gao, Hui-Chang Bi, Zhi-Bin Zhao, Mei-Lan Lian, Zhe-Xiong Lian
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
O. elatus Nakai is a traditional medicine that has been confirmed to exert effective antioxidant and anti-inflammatory functions, and is used for the treatment of different disorders. However, its potential beneficial effects on drug induced hepatoto
Externí odkaz:
https://doaj.org/article/d8d4917ce09c4d73aaccafdcc49c2f19
Autor:
Yichen Han, Zhen-Hua Bian, Si-Yu Yang, Cheng-Bo Wang, Liang Li, Yan-Qing Yang, Aftab A. Ansari, M. Eric Gershwin, Xiaofeng Zeng, Zhe-Xiong Lian, Zhi-Bin Zhao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Primary biliary cholangitis (PBC), an organ-specific autoimmune disease, is characterized by injury to small bile ducts, inflammatory cell infiltrates within the liver, progressive cholestasis, and in some cases, cirrhosis with unclear pathogenesis.
Externí odkaz:
https://doaj.org/article/7ff1b9ffdde748279ff44d139cefa5dd
Autor:
Si-Yu Yang, Jie Long, Meng-Xing Huang, Pan-Yue Luo, Zhen-Hua Bian, Ya-Fei Xu, Cheng-Bo Wang, Shu-Han Yang, Liang Li, Carlo Selmi, M. Eric Gershwin, Zhi-Bin Zhao, Zhe-Xiong Lian
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory B cells (Breg) are considered as immunosuppressive cells. Different subsets of Breg cells have been identified both in human beings and in mice. However, there is a lack of unique markers to identify Breg cells, and the heterogeneity of Br
Externí odkaz:
https://doaj.org/article/39a8ba63a08f4f38808ecc99c6642d05