Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zhi Yang Tam"'
Autor:
Zhi Yang Tam, Sean Pin Ng, Ling Qiao Tan, Chih-Hsien Lin, Dietrich Rothenbacher, Jochen Klenk, Bernhard Otto Boehm, SPC Team, ActiFE Study Group
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Regulation of blood glucose requires precise coordination between different endocrine systems and multiple organs. Type 2 diabetes mellitus (T2D) arises from a dysregulated response to elevated glucose levels in the circulation. Globally, th
Externí odkaz:
https://doaj.org/article/69343e65f84a4c9a91fbf0951728d1b4
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 5, p e1004183 (2015)
The accumulation of mutant mitochondrial DNA (mtDNA) molecules in aged cells has been associated with mitochondrial dysfunction, age-related diseases and the ageing process itself. This accumulation has been shown to often occur clonally, where mutan
Externí odkaz:
https://doaj.org/article/df9ee97b89bf4e5d9d4fc3a3f6e0de66
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76230 (2013)
Accumulation of mitochondrial DNA (mtDNA) mutations has been implicated in a wide range of human pathologies, including neurodegenerative diseases, sarcopenia, and the aging process itself. In cells, mtDNA molecules are constantly turned over (i.e. r
Externí odkaz:
https://doaj.org/article/dbea9a28d97846d6b9cd373e985fa73d
Publikováno v:
The Journals of Gerontology: Series A, 69 (7)
The Journals of Gerontology: Series A, 69 (7)
ISSN:1079-5006
ISSN:1758-535X
ISSN:1079-5006
ISSN:1758-535X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b878cf80ae4ca5514a0747ed53b323
http://doc.rero.ch/record/290701/files/glt210.pdf
http://doc.rero.ch/record/290701/files/glt210.pdf
Autor:
Peter T. C. So, Jie Yan, Surya Pratap Singh, Ziwei Song, Jeon Woong Kang, Hanry Yu, Lisa Tucker Kellogg, Yang Yu, Zhi Yang Tam, Eliza Li Shan Fong, Shuoyu Xu
Publikováno v:
Clinical and Preclinical Optical Diagnostics.
We combined Raman micro-spectroscopy and machine learning techniques to develop a classification model based on a well-established non-alcoholic steatohepatitis (NASH) mouse model, using spectrum pre-processing, biochemical component analysis (BCA) a
Autor:
Peter T. C. So, Shuoyu Xu, Surya Pratap Singh, Lisa Tucker-Kellogg, Hanry Yu, Jie Yan, Yang Yu, Ziwei Song, Eliza Li Shan Fong, Jeon Woong Kang, Zhi Yang Tam
Publikováno v:
PMC
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in developed countries [1]. A subset of individuals with NAFLD progress to non-alcoholic steatohepatitis (NASH), an advanced form of NAFLD which predisposes individuals to ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cceeb65b2ae57e5e3b734a960b15e2b
https://orcid.org/0000-0002-0339-3685
https://orcid.org/0000-0002-0339-3685
Autor:
Anabel-Lise Le Roux, Lisa Tucker-Kellogg, Sophie Kan, Bruno Pontes, Virgile Viasnoff, Laurent Gole, Pere Roca-Cusachs, Anita Joanna Kosmalska, Pascale Monzo, Zhi Yang Tam, Weiwei Luo, Nils C. Gauthier
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
The Journal of Cell Biology
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
The Journal of Cell Biology
Recercat. Dipósit de la Recerca de Catalunya
instname
Pontes et al. show that plasma membrane mechanics exerts an upstream control during cell motility. Variations in plasma membrane tension orchestrate the behavior of the cell leading edge, with increase–decrease cycles in tension promoting adhesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d39bab48bd9492af9aafd43c17e752
http://hdl.handle.net/2445/123547
http://hdl.handle.net/2445/123547
Autor:
Thiam Chye Tan, Chee Wai Ku, John Carson Allen, Zhen Wei Tan, Mark Kit Lim, Zhi Yang Tam, Nguan Soon Tan, Chih-Hsien Lin, Sze Min Lek, Sean Pin Ng
Publikováno v:
BBA Clinical
Threatened miscarriage is the most common gynecological emergency, occurring in about 20% of pregnant women. Approximately one in four of these patients go on to have spontaneous miscarriage and the etiology of miscarriage still remains elusive. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba9bb72a80e5f884dd760e1edaafb4b
https://hdl.handle.net/10356/81152
https://hdl.handle.net/10356/81152
Autor:
Sean Pin Ng, Yin Hoe Yau, Yiyang Song, Hong Zheng Koh, Carol Tan, Susana Geifman Shochat, Nguan Soon Tan, Wei Sheng Loo, Zhi Yang Tam, Chee Chong Choo, Zhen Wei Tan, Pengcheng Zhu, Ziqiang Teo, Yi Siang Ng
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1864(10)
Angiopoietin-like 4 (ANGPTL4) is a secretory protein that can be cleaved to form an N-terminal and a C-terminal protein. Studies performed thus far have linked ANGPTL4 to several cancer-related and metabolic processes. Notably, several point mutation
Autor:
Daniel Ek Kwang Chew, Rinkoo Dalan, King Ho Holden Li, Zhi Yang Tam, Hui Min Tay, Han Wei Hou, Bernhard O. Boehm, Chayakorn Petchakup
Publikováno v:
Scientific Reports
Advanced management of dysmetabolic syndromes such as diabetes will benefit from a timely mechanistic insight enabling personalized medicine approaches. Herein, we present a rapid microfluidic neutrophil sorting and functional phenotyping strategy fo