Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Zhi Qiang Ling"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-27 (2024)
Abstract Progesterone and AdipoQ Receptor 3 (PAQR3) is a member of the AdipoQ receptor. Our previous studies have found that PAQR3 plays a role as a candidate inhibitor in cardiac adenocarcinoma, breast cancer, gastric cancer and colorectal cancer, b
Externí odkaz:
https://doaj.org/article/6a73df3c79dd41ec8d0affd2f761284e
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 16756-16773 (2023)
Abstract Introduction Tumor‐associated bacteria and gut microbiota have gained significant attention in recent years due to their potential role in cancer development and therapeutic response. This review aims to discuss the contributions of intrat
Externí odkaz:
https://doaj.org/article/0445b1e0dc28451aa1b9ff8e45013e7b
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-35 (2023)
Abstract RNA modification has recently become a significant process of gene regulation, and the methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification, methylating various types of RNAs, including mRNA, tRNA, micr
Externí odkaz:
https://doaj.org/article/f4ffb5a4d22d4229973c0a19d8abab56
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract N6-methyladenosine (m6A) is the most prevalent and well-characterized internal chemical modification in eukaryotic RNA, influencing gene expression and phenotypic changes by controlling RNA fate. Insulin-like growth factor-2 mRNA-binding pro
Externí odkaz:
https://doaj.org/article/f46848098a7c47b1aa1ea9014672ebd6
Autor:
Xin Zhu, Jia-jie Xu, Si-si Hu, Jian-guo Feng, Lie-hao Jiang, Xiu-xiu Hou, Jun Cao, Jing Han, Zhi-qiang Ling, Ming-hua Ge
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/59427b0c8e7743649ab5eb43557d1400
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0cfb3f392d6e45dda2366eda96dcddd2
Autor:
Shi‐Bing Li, Yan‐Yan Liu, Li Yuan, Ming‐Fang Ji, Ao Zhang, Hui‐Yu Li, Lin‐Quan Tang, Shuo‐Gui Fang, Hua Zhang, Shan Xing, Man‐Zhi Li, Qian Zhong, Shao‐Jun Lin, Wan‐Li Liu, Peng Huang, Yi‐Xin Zeng, Yu‐Ming Zheng, Zhi‐Qiang Ling, Jian‐Hua Sui, Mu‐Sheng Zeng
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp 1-19 (2020)
Abstract Metabolic reprogramming plays important roles in development and progression of nasopharyngeal carcinoma (NPC), but the underlying mechanism has not been completely defined. In this work, we found INSL5 was elevated in NPC tumor tissue and t
Externí odkaz:
https://doaj.org/article/621a29cd73654baba154f0c200991840
Autor:
Chao Wang, Xingyou Wan, Tong Yu, Zhenyu Huang, Chao Shen, Qian Qi, Sheng Xiang, Xinyuan Chen, Eyal Arbely, Zhi-Qiang Ling, Chen-Ying Liu, Wei Yu
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108021- (2020)
Summary: Phosphoglycerate dehydrogenase (PHGDH) is the first enzyme in the serine synthesis pathway in which it is also the rate-limiting enzyme. It is significantly upregulated in many cancers, especially breast cancer. However, the posttranslationa
Externí odkaz:
https://doaj.org/article/20d089fdb4264a23830286f0b4fb96b1
Autor:
Fu-Long Li, Jin-Ping Liu, Ruo-Xuan Bao, GuoQuan Yan, Xu Feng, Yan-Ping Xu, Yi-Ping Sun, Weili Yan, Zhi-Qiang Ling, Yue Xiong, Kun-Liang Guan, Hai-Xin Yuan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Enhanced glycolysis in cancer cells has been associated with protection from DNA damage. Here the authors show that DNA damaging signals induce acetylation of PFKFB3 at lysine K472 and promote its cytosolic accumulation, which enhances glycolysis, re
Externí odkaz:
https://doaj.org/article/461b17d4756348ec8fa51f6eb566a6ce
Autor:
Zhu Liu, Lian-Lian Hong, Jin-Sen Zheng, Zhe-Nan Ling, Zhi-Long Zhang, Ya-Nan Qi, Xin-Yu Zhang, Tian-Yu Zhu, Jiu-Li Wang, Jing Han, Xiang-Liu Chen, Qi-Ming Yu, Shi Wang, Pei Li, Zhi-Qiang Ling
Publikováno v:
Gastric Cancer. 26:203-219
Background Primary gastric linitis plastica (GLP) is a distinct phenotype of gastric cancer with poor survival. Comprehensive molecular profiles and putative therapeutic targets of GLP remain undetermined. Methods We subjected 10 tumor-normal tissue