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pro vyhledávání: '"Zhi Heng Lau"'
Autor:
Kim S. ROBINSON, Gee Ann TOH, Muhammad Jasrie FIRDAUS, Khek Chian THAM, Pritisha ROZARIO, Chrissie LIM, Ying Xiu TOH, Zhi Heng LAU, Sophie Charlotte BINDER, Jacob MAYER, Carine BONNARD, Florian I. SCHMIDT, John E. A. COMMON, Franklin L. ZHONG
NLRP1 is an innate immune sensor protein that activates inflammasome-driven pyroptotic cell death. Recent work demonstrates that human NLRP1 has evolved to sense viral infections. Whether and how human NLRP1 responds to other infectious agents is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad76428c5948ff4f0a10289c3b7465b3
https://doi.org/10.1101/2023.01.16.524188
https://doi.org/10.1101/2023.01.16.524188
Autor:
Tomasz Próchnicki, Matilde B. Vasconcelos, Kim S. Robinson, Matthew S. J. Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G. Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A. Kufer, Florian I. Schmidt, Franklin L. Zhong, Eicke Latz
Publikováno v:
Nature immunology 24(4), 595-603 (2023). doi:10.1038/s41590-023-01451-y
Upon detecting pathogens or cell stress, several NOD-like receptors (NLRs) form inflammasome complexes with the adapter ASC and caspase-1, inducing gasdermin D (GSDMD)-dependent cell death and maturation and release of IL-1β and IL-18. The triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951cef744dde927be85ce561d1cb4398