Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zhi H Huang"'
Autor:
Violet R. Mukaro, Alex Quach, Michelle E. Gahan, Bernadette Boog, Zhi H. Huang, Xiuhui Gao, Carol Haddad, Suresh Mahalingam, Charles S. Hii, Antonio Ferrante
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Anti-TNF therapy has improved the treatment of inflammatory disease but can predispose to infection and malignancy. Here the authors show an anti-TNF biologic peptide that functionally and selectively targets the TNF-p38 pathway in multiple models of
Externí odkaz:
https://doaj.org/article/6d8d32e467ee4dd0a9417a3616257e88
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 215-226 (2015)
apoE is a multi-functional protein expressed in several cell types and in several organs. It is highly expressed in adipose tissue, where it is important for modulating adipocyte lipid flux and gene expression in isolated adipocytes. In order to inve
Externí odkaz:
https://doaj.org/article/07a58f2dc25940de9a40ef6270a8fc9a
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 202-213 (2013)
The synthesis of apoE by adipocytes has profound effects on adipose tissue lipid flux and gene expression. Using adipose tissue transplantation from wild-type (WT) to apoE knockout (EKO) mice, we show that adipose tissue also contributes to circulati
Externí odkaz:
https://doaj.org/article/504272f63e9348aeb8b780a2d1474166
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 9, Pp 1733-1741 (2011)
Expression of apoE in adipocytes has been shown to have an important role in modulating adipocyte triglyceride (TG) metabolism and gene expression that is independent of circulating and extracellular apoE. The impact of adipocyte expression of common
Externí odkaz:
https://doaj.org/article/f5a1143cd770431e8dfd07f66a59ef3a
Autor:
Dmitry I Gabrilovich, Denis English, J Heinecke, Jay Louis Zweier, A Ferrante, Charles S T Hii, Zhi H Huang, Deborah A Rathjen, Marco Cassatella, N F Fanning, H P Redmond, D Bouchier-hayes, Antal Rot, G Virella, Robert L Roberts, David C Dale, S Nelson, R Strauss
This invaluable volume, written by group of internationally established scientists, presents an overview of the most recent findings on the biology of neutrophils. These cells have become a focus of attention in recent years because of their fascinat
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 202-213 (2013)
The synthesis of apoE by adipocytes has profound effects on adipose tissue lipid flux and gene expression. Using adipose tissue transplantation from wild-type (WT) to apoE knockout (EKO) mice, we show that adipose tissue also contributes to circulati
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 292:E891-E899
Leptin-deficient obese mice ( ob/ob) have decreased circulating growth hormone (GH) and pituitary GH and ghrelin receptor (GHS-R) mRNA levels, whereas hypothalamic GH-releasing hormone (GHRH) and somatostatin (SST) expression do not differ from lean
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:157-162
Objective— Macrophage expression of both apolipoprotein E (apoE) and ABCA1 have been shown to modulate lipid efflux from these cells and to play an important atheroprotective role in vivo. We evaluated the relationship between apoE and ABCA1 for re
Autor:
Nahid Moghaddami, Zhi H. Huang, Maurizio Costabile, Antonio Ferrante, Phulwinder K. Grover, Hubertus Jersmann, Charles S. T. Hii
Publikováno v:
The Journal of Immunology. 171:2616-2624
Arachidonic acid (AA) regulates the function of many cell types, including neutrophils. Although much emphasis has been placed on agonist-induced down-regulation of TNFR, our data show that AA caused a rapid (10–20 min) and dose-dependent (0.5–30
Autor:
Maurizio Costabile, Zhi H. Huang, Andrea J. Bilney, Andrew W. Murray, Deborah Ann Rathjen, Antonio Ferrante, Charles S. T. Hii, Channing J. Der
Publikováno v:
Journal of Biological Chemistry. 273:19277-19282
Although it is well appreciated that arachidonic acid, a second messenger molecule that is released by ligand-stimulated phospholipase A2, stimulates a wide range of cell types, the mechanisms that mediate the actions of arachidonic acid are still po