Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Zhi‐zhong Pan"'
Autor:
Zi-Tong Zhang, Wei-Wei Xiao, Li-Ren Li, Xiao-Jun Wu, Qiao-Xuan Wang, Hui Chang, Xue Tian, Wu Jiang, Jun-Zhong Lin, Rong-Xin Zhang, Wen-Hua Fan, Zhi-Zhong Pan, Rong Zhang, Yuan-Hong Gao
Publikováno v:
EClinicalMedicine, Vol 76, Iss , Pp 102836- (2024)
Summary: Background: Neoadjuvant chemotherapy (NACT) is commonly used to downstage the tumor in locally advanced colon cancer (LACC) and improve the R0 resection rate. Neoadjuvant chemoradiotherapy (NACRT) is the standard treatment for locally advanc
Externí odkaz:
https://doaj.org/article/81b7c57272c64e6f9108845cf633293f
Autor:
De-Shen Wang, Chao Ren, Shan-Shan Li, William Pat Fong, Xiao-Jun Wu, Jian Xiao, Bin-Kui Li, Yun Zheng, Pei-Rong Ding, Gong Chen, Miao-Zhen Qiu, Zhi-Qiang Wang, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Xiao-Zhong Wang, Ling-Yun Wang, De-Jin Xie, Tao Chen, Li-Ren Li, Zhen-Hai Lu, Xiao-Hui Zhai, Tian-Shu Liu, Ying Yuan, Jia-Qi Chen, Qiong Tan, Zhi-Zhong Pan, De-Sen Wan, Rong Zhang, Yun-Fei Yuan, Rui-Hua Xu, Yu-Hong Li
Publikováno v:
PLoS Medicine, Vol 21, Iss 5, p e1004389 (2024)
BackgroundIt remains unclear whether intensification of the chemotherapy backbone in tandem with an anti-EGFR can confer superior clinical outcomes in a cohort of RAS/BRAF wild-type colorectal cancer (CRC) patients with initially unresectable colorec
Externí odkaz:
https://doaj.org/article/b9e6a45661f549378ef2d8ab851edf5e
Autor:
Ji‐Bin Li, Keng‐Jian Ke, Wei‐Li Zhang, Ling‐Yan Wang, Yan‐Ping Wu, Fan Weng, Huan Tian, Zhi‐Yu Qiu, Yin Li, Shi‐Yong Lin, Mei‐Xian Ye, Qing‐Jian Ou, Cheng‐Hua Gong, Zhen‐Hai Lu, Zhi‐Zhong Pan, De‐Sen Wan, Jian‐Hong Peng, Yu‐Jing Fang
Publikováno v:
Cancer Medicine, Vol 11, Iss 22, Pp 4321-4331 (2022)
Abstract Objectives This study aimed to investigate the potential factors associated with adherence to colonoscopy among participants who were preliminarily screened positive in a community‐based colorectal cancer screening program in China. Method
Externí odkaz:
https://doaj.org/article/2173f8b2fe60462eafd5870f85bfa69d
Stage IV colon cancer patients without DENND2D expression benefit more from neoadjuvant chemotherapy
Autor:
Wen-juan Ma, Yukun Chen, Jian-hong Peng, Chaoming Tang, Ling Zhang, Min Liu, Shanshan Hu, Haineng Xu, Hua Tan, Yangkui Gu, Zhi-zhong Pan, Gong Chen, Zhong-guo Zhou, Rong-xin Zhang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-12 (2022)
Abstract According to the EPOC study, chemotherapy could improve 5-year disease-free survival of stage IV colon cancer patients by 8.1%. However, more molecular biomarkers are required to identify patients who need neoadjuvant chemotherapy. DENND2D e
Externí odkaz:
https://doaj.org/article/2a267ae556c64ee1b7fd95e1e8d9c0b8
Autor:
Qiao-Xuan Wang, Shu Zhang, Wei-Wei Xiao, Cheng-Jing Zhou, Hui Chang, Zhi-Fan Zeng, Pei-Qiang Cai, Zhen-Hai Lu, Gong Chen, Pei-Rong Ding, Zhi-Zhong Pan, Xiao-Jun Wu, Yuan-Hong Gao
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Background High dose chemoradiotherapy offers a curative chance for patients with rectal cancer that are unfit or unwilling to undergo surgical resection, yet its long-term survival and functional outcomes have been rarely investigated. Meth
Externí odkaz:
https://doaj.org/article/810bfbd66f154df0bfa9b9d30e71395e
Autor:
Qi Zhao, Feng Wang, Yan-Xing Chen, Shifu Chen, Yi-Chen Yao, Zhao-Lei Zeng, Teng-Jia Jiang, Ying-Nan Wang, Chen-Yi Wu, Ying Jing, You-Sheng Huang, Jing Zhang, Zi-Xian Wang, Ming-Ming He, Heng-Ying Pu, Zong-Jiong Mai, Qi-Nian Wu, Renwen Long, Xiaoni Zhang, Tanxiao Huang, Mingyan Xu, Miao-Zheng Qiu, Hui-Yan Luo, Yu-Hong Li, Dong-Shen Zhang, Wei-Hua Jia, Gong Chen, Pei-Rong Ding, Li-Ren Li, Zheng-Hai Lu, Zhi-Zhong Pan, Rui-Hua Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The ChangKang (Heathy Bowel) project was established to collect molecular and clinical information of a thousand Chinese colorectal cancer patients. Here, the authors present the genomic landscape of the ChangKang cohort and find a subgroup of patien
Externí odkaz:
https://doaj.org/article/ee0548bf4a574cba8d5b0964a7e38b91
Autor:
Ji-Bin Li, Zhi-Yu Qiu, Yu-Xiang Deng, Yin Li, Zhuo-Chen Lin, Yan-Ping Wu, Fan Weng, Huan Tian, Qing-Jian Ou, Cheng-Hua Gong, Zhi-Zhong Pan, De-Sen Wan, Jian-Hong Peng, Yu-Jing Fang
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract Background The positive predictive value (PPV) of high risk factor questionnaire (HRFQ) plus fecal immunochemical test (FIT) as preliminary screening strategy for colorectal-related neoplasia is relatively low. We aim to explore independent
Externí odkaz:
https://doaj.org/article/83099a8620ac42aa9c15b7964b55b6a4
Autor:
Long Bai, Ze‐Yu Lin, Yun‐Xin Lu, Qin Chen, Han Zhou, Qi Meng, Chun‐Ping Lin, Wan‐Lan Huang, Yun‐Le Wan, Zhi‐Zhong Pan, De‐Shen Wang
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 8005-8019 (2021)
Abstract Background The prognostic value of lactate dehydrogenase (LDH) in colorectal cancer patients has remained inconsistent between nonmetastatic and metastatic settings. So far, very few studies have included LDH in the prognostic analysis of cu
Externí odkaz:
https://doaj.org/article/379bb3dd7c62469a931ce8bb0e4b0198
Autor:
Wu Jiang, Wei-Jian Mei, Shuo-Yu Xu, Yi-Hong Ling, Wei-Rong Li, Jin-Bo Kuang, Hao-Sen Li, Hui Hui, Ji-Bin Li, Mu-Yan Cai, Zhi-Zhong Pan, Hui-Zhong Zhang, Li Li, Pei-Rong Ding
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104120- (2022)
Summary: Background: We aimed to develop a deep learning (DL) model to predict DNA mismatch repair (MMR) status in colorectal cancers (CRC) based on hematoxylin and eosin-stained whole-slide images (WSIs) and assess its clinical applicability. Method
Externí odkaz:
https://doaj.org/article/7c458154060c42e6a8afef4581087e25
Autor:
Zi-Xian Wang, Yi-Chen Yao, Zong-Jiong Mai, Wu-Hao Lin, You-Sheng Huang, Ying Jin, Hui-Yan Luo, Dong-Sheng Zhang, Feng-Hua Wang, Feng Wang, Gong Chen, Pei-Rong Ding, Yun-Fei Yuan, Yu-Hong Li, Jin-Hua Huang, Zhi-Zhong Pan, Rui-Hua Xu
Publikováno v:
Engineering, Vol 7, Iss 4, Pp 526-533 (2021)
There is a lack of high-quality, large-scale, real-world evidence from patients with metastatic colorectal cancer (mCRC), especially in China. It remains unclear whether efforts to improve the quality of care for mCRC would improve patient survival o
Externí odkaz:
https://doaj.org/article/f732de77c04a45509f100295641df798