Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zheyi Lin"'
Autor:
Hui Xiong, Bowen Lin, Junyang Liu, Renhong Lu, Zheyi Lin, Chengwen Hang, Wenjun Liu, Lei Zhang, Jie Ding, Huixin Guo, Mingshuai Zhang, Siyu Wang, Zheng Gong, Duanyang Xie, Yi Liu, Dan Shi, Dandan Liang, Zhen Liu, Yi-Han Chen, Jian Yang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-15 (2024)
Abstract The spalt (Sal) gene family has four members (Sall1-4) in vertebrates, all of which play pivotal roles in various biological processes and diseases. However, the expression and function of SALL2 in development are still less clear. Here, we
Externí odkaz:
https://doaj.org/article/7f36bf6a9986410aa90e27140ca18bd1
A new paradigm for generating high-quality cardiac pacemaker cells from mouse pluripotent stem cells
Autor:
Zheyi Lin, Bowen Lin, Chengwen Hang, Renhong Lu, Hui Xiong, Junyang Liu, Siyu Wang, Zheng Gong, Mingshuai Zhang, Desheng Li, Guojian Fang, Jie Ding, Xuling Su, Huixin Guo, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Jian Yang, Yi-Han Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Cardiac biological pacing (BP) is one of the future directions for bradyarrhythmias intervention. Currently, cardiac pacemaker cells (PCs) used for cardiac BP are mainly derived from pluripotent stem cells (PSCs). However, the production of
Externí odkaz:
https://doaj.org/article/df6e07473b8847cf9f3322eccaafe683
Autor:
Chengwen Hang, Mohamed S. Moawad, Zheyi Lin, Huixin Guo, Hui Xiong, Mingshuai Zhang, Renhong Lu, Junyang Liu, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Yi-Han Chen, Jian Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Cardiovascular diseases (CVDs) have the highest mortality worldwide. Human pluripotent stem cells (hPSCs) and their cardiomyocyte derivatives (hPSC-CMs) offer a valuable resource for disease modeling, pharmacological screening, an
Externí odkaz:
https://doaj.org/article/3c628a341eea423facccdc0b34287cd0
Autor:
Huixin Guo, Chengwen Hang, Bowen Lin, Zheyi Lin, Hui Xiong, Mingshuai Zhang, Renhong Lu, Junyang Liu, Dan Shi, Duanyang Xie, Yi Liu, Dandan Liang, Jian Yang, Yi-Han Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Background Transcription factors HAND1 and HAND2 (HAND1/2) play significant roles in cardiac organogenesis. Abnormal expression and deficiency of HAND1/2 result in severe cardiac defects. However, the function and mechanism of HAND1/2 in reg
Externí odkaz:
https://doaj.org/article/3e5e1570bfcc445c934141367de89f64
Autor:
Yanping Zhang, Le Ni, Bowen Lin, Lingjie Hu, Zheyi Lin, Jian Yang, Jinyu Wang, Honghui Ma, Yi Liu, Jianghua Lin, Liang Xu, Liqun Wu, Dan Shi
Publikováno v:
Pharmacological Research. 169:105642
Anthracyclines including doxorubicin (DOX) are still the most widely used and efficacious antitumor drugs, although their cardiotoxicity is a significant cause of heart failure. Despite considerable efforts being made to minimize anthracycline-induce