Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zhewang Lin"'
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/e0617b1d20174c67b17340e2ad076255
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m3C) is a new epitranscriptomic mark on RNAs and METTL8 represents an m3C writ
Externí odkaz:
https://doaj.org/article/1d37dfa6251d462ab7c00e54f1198368
Autor:
Szymon Juszkiewicz, Greg Slodkowicz, Zhewang Lin, Paula Freire-Pritchett, Sew-Yeu Peak-Chew, Ramanujan S Hegde
Publikováno v:
eLife, Vol 9 (2020)
Translation of aberrant mRNAs can cause ribosomes to stall, leading to collisions with trailing ribosomes. Collided ribosomes are specifically recognised by ZNF598 to initiate protein and mRNA quality control pathways. Here we found using quantitativ
Externí odkaz:
https://doaj.org/article/25320fe37bca42ca940a58711529e988
Autor:
Rozario, Pritisha, Pinilla, Miriam, Gorse, Leana, Vind, Anna Constance, Robinson, Kim S., Toh, Gee Ann, Firdaus, Muhammad Jasrie, Martínez, José Francisco, Swat Kim Kerk, Zhewang Lin, Chambers, John C., Bekker-Jensen, Simon, Meunier, Etienne, Franklin Zhong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 1/9/2024, Vol. 121 Issue 2, p1-12, 42p
Autor:
Zhewang Lin1, Gasic, Ivana2, Chandrasekaran, Viswanathan1, Peters, Niklas1, Sichen Shao3, Mitchison, Timothy J.2, Hegde, Ramanujan S.1 rhegde@mrc-lmb.cam.ac.uk
Publikováno v:
Science. 1/3/2020, Vol. 367 Issue 6473, p100-104. 5p. 4 Color Photographs.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Diphthamide is a posttranslational modification that has been known since the 1970s. It is conserved in all eukaryotic cells, and its biosynthesis requires at least seven proteins. However, its exact biological function has remained uncl
Publikováno v:
ACS Chemical Biology. 13:3059-3064
Isozymes are enzymes with similar sequences that catalyze the same reaction in a given species. In Saccharomyces cerevisiae, most isozymes have major isoforms with high expression levels and minor isoforms with little expression in normal growth cond
Autor:
Ivana Gasic, Viswanathan Chandrasekaran, Sichen Shao, Ramanujan S. Hegde, Zhewang Lin, Timothy J. Mitchison, Niklas Peters
Publikováno v:
Science
Cell Res
Cell Res
Mechanism of tubulin autoregulation Cells tightly control the abundance of key housekeeping factors, such as ribosomes and chaperones, to maintain them at optimal levels needed for homeostasis. Most abundance control mechanisms involve feedback regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a695974e6ab42103d76764e72e7fde43
https://europepmc.org/articles/PMC6942541/
https://europepmc.org/articles/PMC6942541/
Publikováno v:
Nature chemical biology
Diphthamide and the tRNA wobble uridine modifications both require Dph3 (DiPHthamide biosynthesis 3) protein as an electron donor for the iron-sulfur clusters in their biosynthetic enzymes. Here, using a proteomic approach, we identified Saccharomyce