Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zhenzi, Cai"'
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
The Organization for Economic Co-operation and Development (OECD) Guidance Document No. 34 and No. 286 on Good In Vitro Method Practices (GIVIMPs) for the development and implementation of in vitro methods for regulatory use in human safety assessmen
Externí odkaz:
https://doaj.org/article/867cd7cce47e45699130fba052b36e2b
Autor:
Lizao, Chen, Fang, Huang, CaiChun, Kei, Jinsong, Zhang, Jing, Sang, Ying, Yang, Rong, Kuang, Xikun, Xiong, Qing, Li, Yanfeng, Liu, Qin, Qin, E, Zhao, Nathalie, Alépée, Gladys, Ouedraogo, Nan, Li, Zhenzi, Cai
Publikováno v:
Mutagenesis. 37:173-181
A novel in vitro 3D micronucleus assay was developed in China using the EpiSkin™ 3D human skin model. This EpiSkin™ Micronucleus Assay showed good predictivity and reproducibility during internal validation and is expected to contribute to in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a2e860d8e43064c453ac45444e3c85
https://doi.org/10.1093/mutage/geac014
https://doi.org/10.1093/mutage/geac014
Autor:
Ming Zhou, Wei Wang, Li Pan, José Cotovio, Nan Li, Jie Qiu, Zhenzi Cai, Yuanji Guo, Yanfeng Liu, Wei Gu, Nathalie Alépée, Lingyan Zhong, Lizao Chen, Dan Chen, Yifeng Li
Publikováno v:
Toxicology in Vitro. 52:321-331
The purpose of present study was to investigate the applicability of reconstructed human epidermis model to identify skin corrosive UN GHS Categories 1A, 1B/1C and non-corrosive chemicals in China. By using a commercialized reconstructed human epider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7abe3d5f49bf2ce075497b0ee010680
https://doi.org/10.1016/j.tiv.2018.07.013
https://doi.org/10.1016/j.tiv.2018.07.013
Publikováno v:
Toxicology in Vitro. 41:159-167
The in vitro EpiSkin™ test method was validated in 2007 by the European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM) as a full replacement method for the Draize acute skin irritation test and adopted in the OECD Test G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99c4536eeae97a66c605ed1e013ff6e
https://doi.org/10.1016/j.tiv.2017.02.009
https://doi.org/10.1016/j.tiv.2017.02.009
Autor:
Chunmei Ding, Nan Li, Nathalie Alépée, Joan Eilstein, Jie Ma, Zhengang Peng, Lingyan Zhong, Zhenzi Cai, Brigitte Faquet, Gladys Ouedraogo, Yanfeng Liu, Lizao Chen
Publikováno v:
Mutagenesis. 36(1)
The European Regulation on Cosmetics (no. 1223/2009) has prohibited the use of animals in safety testing since March 2009 for ingredients used in cosmetics. Irreversible events at the chromosome level (clastogenesis and aneugenesis) are commonly eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1438e019dd090b688c0c724a0f1aca71
https://pubmed.ncbi.nlm.nih.gov/32067034
https://pubmed.ncbi.nlm.nih.gov/32067034
Publikováno v:
Toxicology in Vitro. 65:104778
The need of in vitro alternative methods has been increasing in toxicology research as well as in cosmetic industry in China recently. Following the establishment of China EpiSkin™ skin corrosion and irritation testing methods, both as stand-alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fca23d2a5da88f064e5ccaa2b1727f8
https://doi.org/10.1016/j.tiv.2020.104778
https://doi.org/10.1016/j.tiv.2020.104778
Publikováno v:
International Journal of Cosmetic Science. 38:60-67
In vitro reconstructed human epidermis is a powerful tool for both basic research and industrial applications in dermatology, pharmacology and the cosmetic field.By growing keratinocytes of Chinese origin on a collagen matrix after a submerged cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4953029b87ec1df993b15baba2eca31
https://doi.org/10.1111/ics.12249
https://doi.org/10.1111/ics.12249
Publikováno v:
The Journal of Immunology. 165:6756-6761
To investigate the mechanism underlying the absence of arachidonic acid (AA) release by TNF in TNF-resistant cells, we first performed comparative analysis of phospholipid pools in both TNF-sensitive (MCF7) and their equivalent resistant cells (C1001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f875fa75352288d411b8c14c90ccd4
https://doi.org/10.4049/jimmunol.165.12.6756
https://doi.org/10.4049/jimmunol.165.12.6756
Autor:
Céline Bouquet, Maya Ameyar, Rodica Stancou, Vladimir A. Shatrov, Zhenzi Cai, Hedi Haddada, Salem Chouaib
Publikováno v:
International Journal of Cancer. 85:93-97
We have shown that the loss of p53 function contributed to resistance of tumor cells to TNF-induced cytotoxicity. In the present study, we evaluated the effect of wild-type p53 (wt-p53) expression on TNF sensitivity, by introducing wt-p53 into MCF7/A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a025368eaea402d60b61fd9f46846f01
https://doi.org/10.1002/(sici)1097-0215(20000101)85:1<93::aid-ijc17>3.0.co
https://doi.org/10.1002/(sici)1097-0215(20000101)85:1<93::aid-ijc17>3.0.co
Autor:
Ali Bettaieb, Rodica Stancou, Maya Ameyar, Zhenzi Cai, Vladimir A. Shatrov, Azeddine Atfi, Salem Chouaib
Publikováno v:
Journal of Biological Chemistry. 273:29002-29008
Considerable progress has been made in the understanding of tumor necrosis factor (TNF) signaling; however, the molecular and biochemical basis of tumor resistance to the cytotoxic action of TNF are still not definitively identified yet. Although a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20de6dfe92ee9683c6e26cf09b887047
https://doi.org/10.1074/jbc.273.44.29002
https://doi.org/10.1074/jbc.273.44.29002