Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zhenzhi Chng"'
Autor:
Gary S. L. Peh, Zhenzhi Chng, Heng-Pei Ang, Terence Y. D. Cheng, Khadijah Adnan, Xin-Yi Seah, Benjamin L. George, Kah-Peng Toh, Donald T. Tan, Gary H. F. Yam, Alan Colman, Jodhbir S. Mehta
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Corneal endothelium-associated corneal blindness is the most common indication for corneal transplantation. Restorative corneal transplant surgery is the only option to reverse the blindness, but a global shortage of donor material remains an issue.
Externí odkaz:
https://doaj.org/article/87235556c9a94396802f68fd7af97ad1
Autor:
Zhenzhi Chng, Gary S L Peh, Wishva B Herath, Terence Y D Cheng, Heng-Pei Ang, Kah-Peng Toh, Paul Robson, Jodhbir S Mehta, Alan Colman
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67546 (2013)
Considerable interest has been generated for the development of suitable corneal endothelial graft alternatives through cell-tissue engineering, which can potentially alleviate the shortage of corneal transplant material. The advent of less invasive
Externí odkaz:
https://doaj.org/article/63a09f57312443cc95cc698840e6eda4
Autor:
Ludovic Vallier, Thomas Touboul, Zhenzhi Chng, Minodora Brimpari, Nicholas Hannan, Enrique Millan, Lucy E Smithers, Matthew Trotter, Peter Rugg-Gunn, Anne Weber, Roger A Pedersen
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6082 (2009)
Human embryonic stem cells have unique value for regenerative medicine, as they are capable of differentiating into a broad variety of cell types. Therefore, defining the signalling pathways that control early cell fate decisions of pluripotent stem
Externí odkaz:
https://doaj.org/article/ddf01b0a556047b18a18c13ffed40993
Publikováno v:
Cell Stem Cell. 6:59-70
Summary Human embryonic stem cells (hESCs) rely on fibroblast growth factor and Activin-Nodal signaling to maintain their pluripotency. However, Activin-Nodal signaling is also known to induce mesendoderm differentiation. The mechanisms by which Acti
Autor:
Heng-Pei Ang, Xin-Yi Seah, Zi Xian Ngoh, Zhenzhi Chng, Alan Colman, Jodhbir S. Mehta, Yuen Kuen Cheong, William Sun, Gary S L Peh
Publikováno v:
Investigative ophthalmologyvisual science. 54(7)
Purpose There is a lack of definitive cell surface markers to differentiate cultured human corneal endothelial cells (HCECs) from stromal fibroblasts, which could contaminate HCEC cultures. The aim of our study is to discover cell surface antigens on
Autor:
Gary S L Peh, Wishva Herath, Zhenzhi Chng, Kah-Peng Toh, Heng-Pei Ang, Paul Robson, Terence Y. D. Cheng, Alan Colman, Jodhbir S. Mehta
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67546 (2013)
PLoS ONE
PLoS ONE
Considerable interest has been generated for the development of suitable corneal endothelial graft alternatives through cell-tissue engineering, which can potentially alleviate the shortage of corneal transplant material. The advent of less invasive
Publikováno v:
Vitamins and hormones. 85
Maintenance of a pluripotent cell population during mammalian embryogenesis is crucial for the proper generation of extraembryonic and embryonic tissues to ensure intrauterine survival and fetal development. Pluripotent stem cells derived from early
Maintenance of a pluripotent cell population during mammalian embryogenesis is crucial for the proper generation of extraembryonic and embryonic tissues to ensure intrauterine survival and fetal development. Pluripotent stem cells derived from early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aabadca7f9add7fc179546b1d4766f36
https://doi.org/10.1016/b978-0-12-385961-7.00003-2
https://doi.org/10.1016/b978-0-12-385961-7.00003-2
Autor:
Sasha Mendjan, Matthew Trotter, Lucy E. Smithers, Roger A. Pedersen, Stephanie Brown, Ludovic Vallier, Peter J. Rugg-Gunn, Gabrielle Brons, Zhenzhi Chng, Amelie Martinez, Candy H.-H. Cho, Adrian Kee Keong Teo
The pluripotent status of embryonic stem cells (ESCs) confers upon them the capacity to differentiate into the three primary germ layers, ectoderm,mesoderm and endoderm, from which all the cells of the adult body are derived. An understanding of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885a291dd3a446a3a3fdfc3951c971f2
https://europepmc.org/articles/PMC2687465/
https://europepmc.org/articles/PMC2687465/
Publikováno v:
Regulatory Networks in Stem Cells ISBN: 9781603272261
This chapter covers the different signaling pathways affecting embryonic stem (ES) cells. We discuss those signals governing maintenance of pluripotency, survival and proliferation, and induction of differentiation. We also cover the differences in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2abeb3d766403a638aa348d088c4181d
https://doi.org/10.1007/978-1-60327-227-8_25
https://doi.org/10.1007/978-1-60327-227-8_25