Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zhenzhen, Xun"'
Autor:
Zhenzhen Xun, Huanran Zhou, Mingyi Shen, Yao Liu, Chengcao Sun, Yanhua Du, Zhou Jiang, Liuqing Yang, Qing Zhang, Chunru Lin, Qingsong Hu, Youqiong Ye, Leng Han
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Although hypoxia is known to be associated with immune resistance, the adaptability to hypoxia by different cell populations in the tumor microenvironment and the underlying mechanisms remain elusive. This knowledge gap has hindered the deve
Externí odkaz:
https://doaj.org/article/23fd95d98cd0466eac089c2f0d848fcc
Autor:
Zhenzhen Xun, Xinyu Ding, Yao Zhang, Benyan Zhang, Shujing Lai, Duowu Zou, Junke Zheng, Guoqiang Chen, Bing Su, Leng Han, Youqiong Ye
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Delineating the cellular composition of tumour boundaries in spatial transcriptomics (ST) data is challenging. Here, the authors develop Cottrazm to integrate ST with histological imaging and single-cell data, identify the malignant and non-malignant
Externí odkaz:
https://doaj.org/article/cf04d796051a443b98b4d090dd423c48
Autor:
Jingjing Qi, Hongxiang Sun, Yao Zhang, Zhengting Wang, Zhenzhen Xun, Ziyi Li, Xinyu Ding, Rujuan Bao, Liwen Hong, Wenqing Jia, Fei Fang, Hongzhi Liu, Lei Chen, Jie Zhong, Duowu Zou, Lianxin Liu, Leng Han, Florent Ginhoux, Yingbin Liu, Youqiong Ye, Bing Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Tumour microenvironment profiling during colorectal cancer progression may enable the discovery of therapeutic targets. Here, single cell and spatial RNA sequencing of tumour and adjacent normal tissues reveals an interaction between FAP + fibroblast
Externí odkaz:
https://doaj.org/article/d01eebe932ec4da8b4999091fe015904
Autor:
Huifang Chen, Jiameng Yao, Rujuan Bao, Yu Dong, Ting Zhang, Yanhua Du, Gaoyang Wang, Duan Ni, Zhenzhen Xun, Xiaoyin Niu, Youqiong Ye, Hua-Bing Li
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Abstract Background The four major RNA adenosine modifications, i.e., m6A, m1A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regula
Externí odkaz:
https://doaj.org/article/b3d0ca45a3fa4330843d44dc2dd36ef2
Autor:
Yao Liu, Zhenzhen Xun, Kun Ma, Shuhang Liang, Xianying Li, Shuo Zhou, Linmao Sun, Yufeng Liu, Yanhua Du, Xinyu Guo, Tianming Cui, Huanran Zhou, Jizhou Wang, Dalong Yin, Ruipeng Song, Shugeng Zhang, Wei Cai, Fanzheng Meng, Hongrui Guo, Bo Zhang, Di Yang, Rujuan Bao, Qingsong Hu, Jiabei Wang, Youqiong Ye, Lianxin Liu
Publikováno v:
Journal of Hepatology. 78:770-782
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b56f694901893b3dba8e52c5f823bab
https://doi.org/10.1016/j.jhep.2023.01.011
https://doi.org/10.1016/j.jhep.2023.01.011
Autor:
Yu Dong, Hua-Bing Li, Duan Ni, Rujuan Bao, Yanhua Du, Xiaoyin Niu, Zhenzhen Xun, Huifang Chen, Youqiong Ye, Jiameng Yao, Gaoyang Wang, Ting Zhang
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer
Molecular Cancer
BackgroundThe four major RNA adenosine modifications, i.e., m6A, m1A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regulation in im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165afcb405b1a6738da82394eafd80c6
https://doaj.org/article/b3d0ca45a3fa4330843d44dc2dd36ef2
https://doaj.org/article/b3d0ca45a3fa4330843d44dc2dd36ef2
Autor:
Jingjing, Qi, Hongxiang, Sun, Yao, Zhang, Zhengting, Wang, Zhenzhen, Xun, Ziyi, Li, Xinyu, Ding, Rujuan, Bao, Liwen, Hong, Wenqing, Jia, Fei, Fang, Hongzhi, Liu, Lei, Chen, Jie, Zhong, Duowu, Zou, Lianxin, Liu, Leng, Han, Florent, Ginhoux, Yingbin, Liu, Youqiong, Ye, Bing, Su
Publikováno v:
Nature communications. 13(1)
Colorectal cancer (CRC) is among the most common malignancies with limited treatments other than surgery. The tumor microenvironment (TME) profiling enables the discovery of potential therapeutic targets. Here, we profile 54,103 cells from tumor and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f2f3f3abafb3a622c65e25a49cef96e
https://pubmed.ncbi.nlm.nih.gov/35365629
https://pubmed.ncbi.nlm.nih.gov/35365629
Autor:
Huifang Chen, Jiameng Yao, Rujuan Bao, Dong, Yu, Zhang, Ting, Yanhua Du, Gaoyang Wang, Ni, Duan, Zhenzhen Xun, Xiaoyin Niu, Youqiong Ye, Li, Hua-Bing
Additional file 1 : Figure S1. Overview of study design. (A) Flowchart of the steps in the performed analyses. Figure S2. Analysis of mutation frequency and CNV in TCGA- COAD/READ. (A) The mutation frequency of RNA modification “writers” among 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e0618179426cc3c64df11a68675e45
Autor:
Yao Zhang1, Jiaxin Wang1, Hongxiang Sun1,2, Zhenzhen Xun1,2, Zirui He3, Yizhou Zhao1, Jingjing Qi1,2, Sishen Sun1, Qidi Yang1, Yubei Gu1, Ling Zhang1, Chunhua Zhou1, Youqiong Ye1,2, Ningbo Wu1,2 wuningbo@shsmu.edu.cn, Duowu Zou1 zdwrjxh66@sjtu.edu.cn, Bing Su1,2 bingsu@sjtu.edu.cn
Publikováno v:
Journal of Clinical Investigation. 9/17/2024, Vol. 134 Issue 18, p1-16. 16p.