Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Zhenzhen, Hou"'
Autor:
Yusheng Liu, Wenrong Tao, Shuang Wu, Yiwei Zhang, Hu Nie, Zhenzhen Hou, Jingye Zhang, Zhen Yang, Zi-Jiang Chen, Jiaqiang Wang, Falong Lu, Keliang Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Oocyte in vitro maturation is a technique in assisted reproductive technology. Thousands of genes show abnormally high expression in in vitro maturated metaphase II (MII) oocytes compared to those matured in vivo in bovines, mice, and humans
Externí odkaz:
https://doaj.org/article/24e3802812714f3e98aef8506f610122
Autor:
Keliang Wu, Dongdong Fan, Han Zhao, Zhenbo Liu, Zhenzhen Hou, Wenrong Tao, Guanling Yu, Shenli Yuan, Xiaoxiao Zhu, Mengyao Kang, Yong Tian, Zi-Jiang Chen, Jiang Liu, Lei Gao
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-24 (2023)
Abstract It remains poorly understood about the regulation of gene and transposon transcription during human early embryogenesis. Here, we report that broad H3K27ac domains are genome-widely distributed in human 2-cell and 4-cell embryos and transit
Externí odkaz:
https://doaj.org/article/154cd07c63fc4de7bec34569b888a103
Autor:
Dan Liang, Aleksei Mikhalchenko, Hong Ma, Nuria Marti Gutierrez, Tailai Chen, Yeonmi Lee, Sang-Wook Park, Rebecca Tippner-Hedges, Amy Koski, Hayley Darby, Ying Li, Crystal Van Dyken, Han Zhao, Keliang Wu, Jingye Zhang, Zhenzhen Hou, Seongjun So, Jongsuk Han, Jumi Park, Chong-Jai Kim, Kai Zong, Jianhui Gong, Yilin Yuan, Ying Gu, Yue Shen, Susan B. Olson, Hui Yang, David Battaglia, Thomas O’Leary, Sacha A. Krieg, David M. Lee, Diana H. Wu, P. Barton Duell, Sanjiv Kaul, Jin-Soo Kim, Stephen B. Heitner, Eunju Kang, Zi-Jiang Chen, Paula Amato, Shoukhrat Mitalipov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
DNA repair in response to DSBs in the preimplantation embryo is hard to analyze. Here the authors show that over 25% of pre-existing heterozygous loci in control single blastomere samples appeared as homozygous after whole genome amplification, there
Externí odkaz:
https://doaj.org/article/ba06b7898e994b68a92e8beb9b442fb5
Autor:
Shenli Yuan, Jianhong Zhan, Jingye Zhang, Zhenbo Liu, Zhenzhen Hou, Chuanxin Zhang, Lizhi Yi, Lei Gao, Han Zhao, Zi-Jiang Chen, Jiang Liu, Keliang Wu
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Although parental genomes undergo extensive epigenetic reprogramming to be equalized after fertilization, whether they play different roles in human zygotic genome activation (ZGA) remains unknown. Here, we mapped parental transcriptomes by
Externí odkaz:
https://doaj.org/article/881b553b8e09412d89a500eb285298f3
Autor:
Chuanxin Zhang, Xueqi Dong, Xiaoyu Yin, Xinyi Yuan, Jiawei Wang, Jinzhu Song, Zhenzhen Hou, Cheng Li, Keliang Wu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 252, Iss , Pp 114612- (2023)
2-bromoacetamide (BAcAm), a new class of disinfection by-products (DBPs), is widely detected in drinking water across the world. Reports of the high cytogenetic toxicity of BAcAm have aroused public attention concerning its toxic effects on early emb
Externí odkaz:
https://doaj.org/article/7ff7219a706f4347bd5ac75aa01327a8
Autor:
Xu Ye, Yingjin Chen, Xinyu Zhu, Jiahui Guo, Da Xie, Zhenzhen Hou, Shangen Xu, Junwei Zhou, Liurong Fang, Dang Wang, Shaobo Xiao
Publikováno v:
Evolutionary Applications, Vol 13, Iss 9, Pp 2246-2253 (2020)
Abstract Deltacoronavirus is the last identified Coronaviridae subfamily genus. Differing from other coronavirus (CoV) genera, which mainly infect birds or mammals, deltacoronaviruses (δ‐CoVs) reportedly infect both animal types. Recent studies sh
Externí odkaz:
https://doaj.org/article/6db69970dd844fba9d48d97a9e5f8c22
Autor:
Lin Yan, Zhenzhen Hou, Jinnan Ma, Hongmei Wang, Jie Gao, Chenjuan Zeng, Qin Chen, Bisong Yue, Xiuyue Zhang
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
The complete mitochondrial genome of Episymploce splendens, 15,802 bp in length, was determined and annotated in this study. The mito-genome included 13 PCGs, 20 tRNAs and 2 rRNAs. Unlike most typical mito-genomes with conservative gene arrangement a
Externí odkaz:
https://doaj.org/article/8f380507d9b549919fe78d4acf82e370
Autor:
Chengrui Zhu, Zhenzhen Hou, Ran Zhu, Baosen Zhou, Yini Sun, Zhiliang Li, Xu Li, Renyu Ding, Zhenggang Luan, Yingjian Liang, Liang Wang, Xiaochun Ma
Publikováno v:
Surgery. 173:1303-1310
Autor:
Yusheng Liu, Han Zhao, Fanghong Shao, Yiwei Zhang, Hu Nie, Jingye Zhang, Cheng Li, Zhenzhen Hou, Zi-Jiang Chen, Jiaqiang Wang, Bing Zhou, Keliang Wu, Falong Lu
Publikováno v:
Nature Structural & Molecular Biology. 30:200-215
Poly(A)-tail-mediated post-transcriptional regulation of maternal mRNAs is vital in the oocyte-to-embryo transition (OET). Nothing is known about poly(A) tail dynamics during the human OET. Here, we show that poly(A) tail length and internal non-A re
Autor:
Li Wu, You Wu, Bing Peng, Zhenzhen Hou, Yu Dong, Kang Chen, Mingyue Guo, Han Li, Xia Chen, Xiaochen Kou, Yanhong Zhao, Yan Bi, Yixuan Wang, Hong Wang, Rongrong Le, Lan Kang, Shaorong Gao
Publikováno v:
Stem Cell Reports, Vol 9, Iss 5, Pp 1692-1705 (2017)
Summary: Mammalian oocytes possess fascinating unknown factors, which can reprogram terminally differentiated germ cells or somatic cells into totipotent embryos. Here, we demonstrate that oocyte-specific homeobox 1 (Obox1), an oocyte-specific factor
Externí odkaz:
https://doaj.org/article/ba6f0eddd67f4faebd1222507ec774e5