Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Zhenyuan Tang"'
Autor:
Xiaoli Tian, Fu Li, Zhenyuan Tang, Song Wang, Kangkang Weng, Dan Liu, Shaoyong Lu, Wangyu Liu, Zhong Fu, Wenjun Li, Hengwei Qiu, Min Tu, Hao Zhang, Jinghong Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Metal-organic frameworks (MOFs) with diverse chemistry, structures, and properties have emerged as appealing materials for miniaturized solid-state devices. The incorporation of MOF films in these devices, such as the integrated microelectro
Externí odkaz:
https://doaj.org/article/02a6a6aed69f43d89f71e4470e55cdc2
Autor:
Yansheng Ye, Erin R. Tyndall, Van Bui, Zhenyuan Tang, Yan Shen, Xuejun Jiang, John M. Flanagan, Hong-Gang Wang, Fang Tian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The E2-like enzyme human Atg3 catalyses the transfer of ubiquitin-like mammalian LC3 to the lipid phosphatidylethanolamine during autophagosome formation. Here, the authors combine NMR measurements with in vitro biochemical and in vivo cellular assay
Externí odkaz:
https://doaj.org/article/fa4540e2842d4d0c8a33b0010d3d637d
Autor:
Yoshinori Takahashi, Haiyan He, Zhenyuan Tang, Tatsuya Hattori, Ying Liu, Megan M. Young, Jacob M. Serfass, Longgui Chen, Melat Gebru, Chong Chen, Carson A. Wills, Jennifer M. Atkinson, Han Chen, Thomas Abraham, Hong-Gang Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
During autophagy, phagophores elongate to form double-membrane vesicles but the mechanism behind their closure is unknown. Here, the authors develop an autophagy assay and find a role for the endosomal sorting complexes required for transport compone
Externí odkaz:
https://doaj.org/article/dc0bd3a5e9b64caca02caa285ccc24af
Autor:
Zhenyuan Tang, Yoshinori Takahashi, Haiyan He, Tatsuya Hattori, Chong Chen, Xinwen Liang, Han Chen, Megan M. Young, Hong-Gang Wang
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1744-1757.e5 (2019)
Summary: During autophagy, phagophores grow into double-membrane vesicles called autophagosomes, but the underlying mechanism remains unclear. Here, we show a critical role of Atg2A in phagophore expansion. Atg2A translocates to the phagophore at the
Externí odkaz:
https://doaj.org/article/4a271395e6744171aaf488b1eede2b98
Though silicon suboxide (SiOx, 02) was prepared via tetraethyl orthosilicate (TEOS) hydrolyzed, and lithium fluoride (LiF) was introduced in situ, and then SiO2/LiF was covered with pyrolyzed sucrose to obtain SiOx/LiF@C. Large elastic modulus, low s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9a298d8d09e2b913c4c63514da2f20
https://doi.org/10.21203/rs.3.rs-2823421/v1
https://doi.org/10.21203/rs.3.rs-2823421/v1
Autor:
Yoshinori Takahashi, Tatsuya Hattori, Longgui Chen, Carson A. Wills, Hong Gang Wang, Zhenyuan Tang, Xinwen Liang
Publikováno v:
Cell Death Differ
Autophagosomal membranes can serve as activation platforms for intracellular death-inducing signaling complexes (iDISCs) to initiate Caspase-8-dependent apoptosis. In this study, we explore the impact of ESCRT-III-dependent phagophore closure on iDIS
Autor:
Xiaoming Liu, Thomas Abraham, Nicholas J. Buchkovich, Yoshinori Takahashi, Hong Gang Wang, Megan M. Young, Zhenyuan Tang, Han Chen, Xinwen Liang, Tatsuya Hattori, Haiyan He, Yuka Imamura-Kawasawa
Publikováno v:
The Journal of Cell Biology
Takahashi et al. perform a genome-wide CRISPR screen using the HaloTag-LC3 assay to gain insight into the mechanisms of phagophore closure. They identify a role for VPS37A in coordinating the ESCRT assembly on the phagophore for membrane closure.
Autor:
Yoshinori Takahashi, Jason Webb, Zissis C. Chroneos, E. Yau, Sinisa Dovat, Zhenyuan Tang, Todd M. Umstead, Marykate Carillo, Chunhua Song, Yuka Imamura Kawasawa, Yan Chen
Publikováno v:
Immunobiology
Macrophages play an important role in maintaining tissue homeostasis, from regulating the inflammatory response to pathogens to resolving inflammation and aiding tissue repair. The surfactant protein A (SP-A) receptor SP-R210 (MYO18A) has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7bd83663ec1cc6834032b9d0f0a3d3
https://europepmc.org/articles/PMC8863115/
https://europepmc.org/articles/PMC8863115/
Publikováno v:
International Journal of Heat and Mass Transfer. 188:122634
Autor:
Van Bui, Hong Gang Wang, Erin R. Tyndall, Xuejun Jiang, Fang Tian, John M. Flanagan, Yan Shen, Zhenyuan Tang, Yansheng Ye
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
During autophagy the enzyme Atg3 catalyzes the covalent conjugation of LC3 to the amino group of phosphatidylethanolamine (PE) lipids, which is one of the key steps in autophagosome formation. Here, we have demonstrated that an N-terminal conserved r