Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Zhenyu Ou"'
Autor:
Longxiang Wu, Zhenyu Ou, Peihua Liu, Cheng Zhao, Shiyu Tong, Ruizhe Wang, Yangle Li, Junbin Yuan, Minfeng Chen, Benyi Fan, Xiongbing Zu, Yongjie Wang, Jianing Tang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Prostate cancer (PC) is the most common neoplasm and is the second leading cause of cancer-related deaths in men worldwide. The Hippo tumor suppressor pathway is highly conserved in mammals and plays an important role in carcinoge
Externí odkaz:
https://doaj.org/article/dbcd77c874c14da193b3eb3f41a7c0e5
Autor:
Huihuang Li, Jinbo Chen, Zhenghao Li, Minfeng Chen, Zhenyu Ou, Miao Mo, Ruizhe Wang, Shiyu Tong, Peihua Liu, Zhiyong Cai, Chunyu Zhang, Zhi Liu, Dingshan Deng, Jinhui Liu, Chunliang Cheng, Jiao Hu, Xiongbing Zu
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Although immune checkpoint blockade (ICB) therapies have been approved for bladder cancer (BLCA), only a minority of patients respond to these therapies, and there is an urgent need to explore combined therapies. Systematic multi‐omics ana
Externí odkaz:
https://doaj.org/article/93d943543f234e55a0ab440f97643444
Autor:
Zhiyong Cai, Jinbo Chen, Zhengzheng Yu, Huihuang Li, Zhi Liu, Dingshan Deng, Jinhui Liu, Chunliang Chen, Chunyu Zhang, Zhenyu Ou, Minfeng Chen, Jiao Hu, Xiongbing Zu
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract To improve response rate of monotherapy of immune checkpoint blockade (ICB), it is necessary to find an emerging target in combination therapy. Through analyzing tumor microenvironment (TME)‐related indicators, it is validated that BCAT2 s
Externí odkaz:
https://doaj.org/article/a52bcc877b1a4b03805e5278af99f149
Autor:
Huihuang Li, Jiao Hu, Xiongbing Zu, Minfeng Chen, Jinbo Chen, Yihua Zou, Ruoping Deng, Gang Qin, Wenze Li, Jiansheng Tang, Dingshan Deng, Jinhui Liu, Chunliang Cheng, Yu Cui, Zhenyu Ou
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Although neoadjuvant chemotherapy (NAC) has become the standard treatment option for muscle invasive bladder carcinoma (MIBC), its application is still limited because of the lack of biomarkers for NAC prediction.Methods: We conducted a t
Externí odkaz:
https://doaj.org/article/9888ade8657946a1972046f0b9e754c6
Autor:
Dingshan Deng, Fenglian Liu, Zhi Liu, Zuowei Wu, Yunbo He, ChunYu Zhang, Xiongbin Zu, Zhenyu Ou, Yongjie Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundBladder carcinoma (BLCA) is a heterogeneous disease that makes it difficult to achieve proper individual treatment and predict prognosis. This study aimed to develop a risk score from a new perspective of pyroptosis and guide accurate treat
Externí odkaz:
https://doaj.org/article/eb49513dfee14beeb7ebf5e8f7b2c81c
Autor:
Zhenglin Yi, Zhenyu Ou, Jiao Hu, Dongxu Qiu, Chao Quan, Belaydi Othmane, Yongjie Wang, Longxiang Wu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Objectives: To evaluate a new deep neural network (DNN)–based computer-aided diagnosis (CAD) method, namely, a prostate cancer localization network and an integrated multi-modal classification network, to automatically localize prostate cancer on m
Externí odkaz:
https://doaj.org/article/5edab2e652444f0ab5df95d4fdb275c2
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Leydig cells reflect the activation of inflammation, decrease of androgen production, inhibition of cell growth and promotion of cell apoptosis under orchitis. Maternally expressed gene 3 (MEG3) exerts a crucial role in various hu
Externí odkaz:
https://doaj.org/article/25696b2131054a90b3a09bbec538a175
Autor:
Longxiang Wu, Shiqi Xiang, Xiheng Hu, Miao Mo, Cheng Zhao, Yi Cai, Shiyu Tong, Huichuan Jiang, Linxiao Chen, Zhi Wang, Wei Xiong, Zhenyu Ou
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 1, Pp 363-373 (2020)
Abstract Background A high prevalence of osteoblastic bone metastases is characteristic of prostate cancer. Prostate‐specific antigen (PSA) is a serine protease uniquely produced by prostate cancer cells and is an important serological marker for p
Externí odkaz:
https://doaj.org/article/24dadf9bf4f34fb9ab8ac0d8d9758486
Autor:
Zhenyu Ou, Kai Li, Ting Yang, Ying Dai, Mohan Chandra, Jun Ning, Yongli Wang, Ran Xu, Tangjie Gao, Yu Xie, Qing He, Yuanwei Li, Qin Lu, Long Wang, Zhuo Song
Publikováno v:
Clinical and Translational Medicine, Vol 9, Iss 1, Pp 1-12 (2020)
Abstract Background The present study sought to identify a panel of DNA markers for noninvasive diagnosis using cell-free DNA (cfDNA) from urine supernatant or cellular DNA from urine sediments of hematuria patients. A panel of 48 bladder cancer-spec
Externí odkaz:
https://doaj.org/article/ae8d6ccf08144daab3ec6369bbf0eae4
Autor:
Zhi Liu, Tiezheng Qi, Xiaowen Li, Yiyan Yao, Belaydi Othmane, Jinbo Chen, Xiongbing Zu, Zhenyu Ou, Jiao Hu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe TGF-β pathway plays critical roles in numerous malignancies. Nevertheless, its potential role in prognosis prediction and regulating tumour microenvironment (TME) characteristics require further elucidation in bladder cancer (BLCA).Met
Externí odkaz:
https://doaj.org/article/5b68ca9f25b54593953c6e8e77f20cdd