Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Zhenxing Guo"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Single-cell RNA-sequencing (scRNA-seq) provides gene expression profiles of individual cells from complex samples, facilitating the detection of cell type-specific marker genes. In scRNA-seq experiments with multiple donors, the population l
Externí odkaz:
https://doaj.org/article/efe615093ae54b899589812e848cafab
Autor:
Jianfei Yan, Bo Gao, Chenyu Wang, Weicheng Lu, Wenpin Qin, Xiaoxiao Han, Yingying Liu, Tao Li, Zhenxing Guo, Tao Ye, Qianqian Wan, Haoqing Xu, Junjun Kang, Naining Lu, Changhe Gao, Zixuan Qin, Chi Yang, Jisi Zheng, Pei Shen, Lina Niu, Weiguo Zou, Kai Jiao
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Heterotopic ossification (HO) comprises the abnormal formation of ectopic bone in extraskeletal soft tissue. The factors that initiate HO remain elusive. Herein, we found that calcified apoptotic vesicles (apoVs) led to increased calcificati
Externí odkaz:
https://doaj.org/article/22adf82707964cc0ba195999fe1c9704
Publikováno v:
Brain and Behavior, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Study objectives Primary insomnia (PI) triggers a decline in cognitive function, and the thalamus plays an integral role in this process; however, the mechanisms are unclear. The purpose of this study was to investigate the altered functiona
Externí odkaz:
https://doaj.org/article/b79ec696ab8941c4bd7a7eebfee80a47
Autor:
Zhenxing Guo, Daoyu Duan, Wen Tang, Julia Zhu, William S Bush, Liangliang Zhang, Xiaofeng Zhu, Fulai Jin, Hao Feng
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011875 (2024)
Recently, novel biotechnologies to quantify RNA modifications became an increasingly popular choice for researchers who study epitranscriptome. When studying RNA methylations such as N6-methyladenosine (m6A), researchers need to make several decision
Externí odkaz:
https://doaj.org/article/da5ae20e7b974b2ab7cbc1bd6a06ceab
Publikováno v:
Buildings, Vol 14, Iss 7, p 2154 (2024)
With the background of rural revitalization, the urgent demand for energy conservation and improved living quality arises alongside the issues of high energy consumption and low comfort in residential buildings. Located in a region with a hot summer
Externí odkaz:
https://doaj.org/article/24f63ebc43bc41ffb51919975b62b32e
Autor:
Min Liao, Ruiqing Chen, Yang Yang, Hanqing He, Liqian Xu, Yuxuan Jiang, Zhenxing Guo, Wei He, Hong Jiang, Jianwei Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 678-691 (2022)
Aging-elevated DNMT3A R882H-driven clonal hematopoiesis (CH) is a risk factor for myeloid malignancies remission and overall survival. Although some studies were conducted to investigate this phenomenon, the exact mechanism is still under debate. In
Externí odkaz:
https://doaj.org/article/42177ab4bb58489ca72aea79d39505e0
Autor:
Min Liao, Qiongye Dong, Ruiqing Chen, Liqian Xu, Yuxuan Jiang, Zhenxing Guo, Min Xiao, Wei He, Changcai Cao, Ronghua Hu, Wanling Sun, Hong Jiang, Jianwei Wang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract DNA (cytosine-5)-methyltransferase 3A (DNMT3A) mutations occur in ~20% of de novo acute myeloid leukemia (AML) patients, and >50% of these mutations in AML samples are heterozygous missense alterations within the methyltransferase domain at
Externí odkaz:
https://doaj.org/article/429b1f456dfa407ebb8dba27d084ce19
Autor:
Jiahui Gao, Lin Zhang, Jingfang Zhu, Zhenxing Guo, Miaoran Lin, Linxin Bai, Peiyun Zheng, Weilin Liu, Jia Huang, Zhizhen Liu
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 497 (2023)
Objective: Older adults with sleep disorders (SDs) show impaired working memory abilities, and working memory processes are closely related to the prefrontal cortex (PFC). However, the neural mechanism of working memory impairment in older adults wit
Externí odkaz:
https://doaj.org/article/ccc4388df7d141c58793408a744fd9e6
Autor:
Andrew M. Shafik, Feiran Zhang, Zhenxing Guo, Qing Dai, Kinga Pajdzik, Yangping Li, Yunhee Kang, Bing Yao, Hao Wu, Chuan He, Emily G. Allen, Ranhui Duan, Peng Jin
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background N6-methyladenosine (m6A) modification is known to impact many aspects of RNA metabolism, including mRNA stability and translation, and is highly prevalent in the brain. Results We show that m6A modification displays temporal and s
Externí odkaz:
https://doaj.org/article/cea64a1bde4e4e2a803a490e79c90888
Autor:
Wenyan Xu, Zhenxing Guo
Publikováno v:
SAGE Open Medical Case Reports, Vol 10 (2022)
Hemophagocytic lymphohistiocytosis is a rare and almost universally fatal disease in adults. A 60-year-old female patient presented to our hospital with a 3-day history of weakness and anorexia. Physical examination revealed severe pallor without lym
Externí odkaz:
https://doaj.org/article/08d21eab019d41fc8d4b57e0cea8a1a0