Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Zhenwu Luo"'
Autor:
Zhenwu Luo, Wei Jiang
Publikováno v:
MethodsX, Vol 12, Iss , Pp 102698- (2024)
Background. Up to 20% of people with HIV (PWH) fail to recover their CD4+ T cell counts to levels similar to healthy controls after suppressive antiretroviral therapy (ART). Immune non-responders (INRs) are PWH on suppressive ART with CD4+ T cell cou
Externí odkaz:
https://doaj.org/article/8970f0a821ef42a282380d24bc757e0d
Autor:
Wanqi Ni, Li Ren, Lingjie Liao, Dan Li, Zhenwu Luo, Meiling Zhu, Ying Liu, Hui Xing, Zheng Wang, Yiming Shao
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLong-term non-progressors (LTNPs) with HIV infection can naturally control viral replication for up to a decade without antiretroviral therapy (ART), but the underlying mechanisms of this phenomenon remain elusive.MethodsTo investigate the
Externí odkaz:
https://doaj.org/article/f90e944f580d41599f3d8d55169df326
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a47631ce44c94038bad2cc2e57f2224a
Autor:
Xiaoyu Fu, Da Cheng, Zhenwu Luo, Sonya L. Heath, Ruth Adekunle, John E McKinnon, Lisa Martin, Zizhang Sheng, Enrique Espinosa, Wei Jiang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background . Up to 20% of people with HIV (PWH) who undergo virologically suppressed antiretroviral therapy (ART) fail to experience complete immune restoration. We recently reported that plasma anti-CD4 IgG (antiCD4IgG) autoantibodies from
Externí odkaz:
https://doaj.org/article/00b2ab0e983f40cf815a445cc05446ab
Autor:
Jie Zhang, Zhi-wei Ye, Paramita Chakraborty, Zhenwu Luo, John Culpepper, Muhammad Aslam, Leilei Zhang, Katarina Johansson, Jesper Z. Haeggström, Jianqiang Xu, Magnus Olsson, Danyelle M. Townsend, Shikhar Mehrotra, Ralf Morgenstern, Kenneth D. Tew
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106899- (2023)
While recent targeted and immunotherapies in malignant melanoma are encouraging, most patients acquire resistance, implicating a need to identify additional drug targets to improve outcomes. Recently, attention has been given to pathways that regulat
Externí odkaz:
https://doaj.org/article/5d9d42b0e955458aadc407c65b31b648
Autor:
Zhenwu Luo, Sonya L. Health, Min Li, Hyojik Yang, Yongxia Wu, Michael Collins, Steven G. Deeks, Jeffrey N. Martin, Alison Scott, Wei Jiang
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104037- (2022)
Summary: Background: In HIV infection, even under long-term antiretroviral therapy (ART), up to 20% of HIV-infected individuals fail to restore CD4+ T cell counts to the levels similar to those of healthy controls. The mechanisms of poor CD4+ T cell
Externí odkaz:
https://doaj.org/article/0d7ae50991c14a8ca41749dde00904fa
Autor:
Zhenwu Luo, Min Li, Tai-Wei Li, Zongyang Lv, Zhiwei Ye, William J. Cisneros, Jie Zhang, Lingmin Yuan, Judd F. Hultquist, Stephen A. Migueles, Lei Huang, Jian Zhu, Wei Jiang
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT A rare subset of HIV-infected individuals, termed elite controllers (ECs), can maintain long-term control over HIV replication in the absence of antiretroviral therapy (ART). To elucidate the biological mechanism of resistance to HIV replica
Externí odkaz:
https://doaj.org/article/fe11dcfbd9d04e098d48806bfdf826ec
Autor:
Da Cheng, Zhenwu Luo, Xiaoyu Fu, Sophie Stephenson, Clara Di Germanio, Philip J. Norris, Dietmar Fuchs, Lishomwa C. Ndhlovu, Quan-zhen Li, Henrik Zetterberg, Magnus Gisslen, Richard W. Price, Shifang Peng, Wei Jiang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4+
Externí odkaz:
https://doaj.org/article/5aae1f4d2d714f9db84cf5721ad8de34
Autor:
Zhenwu Luo, Sylvia Fitting, Catrina Robinson, Andreana Benitez, Min Li, Yongxia Wu, Xiaoyu Fu, Davide Amato, Wangbin Ning, Nicholas Funderburg, Xu Wang, Zejun Zhou, Xuezhong Yu, Amanda Wagner, Xiaomei Cong, Wanli Xu, Kendra Maas, Bethany J. Wolf, Lei Huang, Jeremy Yu, Alison Scott, Aimee Mcrae-Clark, Eric D. Hamlett, Wei Jiang
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103701- (2021)
Background: Little is known about chronic cannabis smoking-associated oral microbiome and its effects on central nervous system (CNS) functions. Methods: In the current study, we have analyzed the saliva microbiome in individuals who chronically smok
Externí odkaz:
https://doaj.org/article/1efa300385834349ae3f982625ed84e1
Autor:
Zhenwu Luo, Min Li, Yongxia Wu, Zhefeng Meng, Lisa Martin, Lumin Zhang, Elizabeth Ogunrinde, Zejun Zhou, Shenghui Qin, Zhuang Wan, Maria Anna Julia Westerink, Stephanie Warth, Hui Liu, Ping Jin, David Stroncek, Quan-Zhen Li, Ena Wang, Xueling Wu, Sonya L. Heath, Zihai Li, Alexander V. Alekseyenko, Wei Jiang
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background Increased autoreactive antibodies have been reported in HIV disease; however, the mechanism accounting for autoantibody induction in HIV remains unknown. Results Herein, we show that seasonal influenza vaccination induces autoanti
Externí odkaz:
https://doaj.org/article/449377d5ac14496982dff9d66f66a81d