Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Zhentian Fang"'
2
6-Iodopurine as a Versatile Building Block for RNA Purine Architecture Modifications
Autor: Yalun Xie, Zhentian Fang, Wei Yang, Zhiyong He, Kun Chen, Panpan Heng, Baoshan Wang, Xiang Zhou
Publikováno v: Bioconjugate Chemistry. 33:353-362
Natural modified bases in RNA were found to be indispensable for basic biological processes. In addition, artificial RNA modifications have been a versatile toolbox for the study of RNA interference, structure, and dynamics. Here, we present a chemic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99041ddd743d3d16d614ba700b0bd817
https://doi.org/10.1021/acs.bioconjchem.1c00595
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4
5-Formyluracil targeted biochemical reactions with proteins inhibit DNA replication, induce mutations and interference gene expression in living cells
Autor: Kaiyuan Zhang, Xiang Zhou, Zhentian Fang, Wei Yang, Guangrong Zou, Chaoxing Liu
Publikováno v: Chinese Chemical Letters. 32:3252-3256
Covalent DNA–protein cross-links are toxic DNA lesions that interfere with essential biological processes, which can cause serious biological consequences, such as genomic instability and protein misexpression. 5-Formyluracil (5fU) as an important
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f5e7f279abf37d9cd19cdad2f349b05
https://doi.org/10.1016/j.cclet.2021.02.036
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6
Photoactive G-Quadruplex Ligand Identifies Multiple G-Quadruplex-Related Proteins with Extensive Sequence Tolerance in the Cellular Environment
Autor: Haomiao Su, Kun Chen, Ping Wang, Yuqi Chen, Qi Wang, Yage Chen, Xiang Zhou, Zhentian Fang, Shaoqing Han, Jinglei Xu, Ziang Lu, Bi-Feng Yuan
Publikováno v: Journal of the American Chemical Society. 143:1917-1923
G-Quadruplex (G4) is a noncanonical nucleic acid secondary structure with multiple biofunctions. Identifying G4-related proteins (G4RPs) is important for understanding the roles of G4 in biology. Current methods to identify G4RPs include discovery fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d292827cc943f8ebc595d196bf144fd
https://doi.org/10.1021/jacs.0c10792
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7
Photocaged probes for spatiotemporal imaging
Autor: Guangrong Zou, Shaokang Jia, Tian Tian, Wei Yang, Chaoxing Liu, Xiang Zhou, Xiong Zhang, Xiaocheng Weng, Zhentian Fang, Mingkai Chen
Publikováno v: Sensors and Actuators B: Chemical. 288:113-119
Two compounds with nitrobenzene-derived caging groups were designed and synthesized for cells and tissues imaging. After 350 nm irradiation, the two reagents can realize highly efficient fluorescence turn on with large Stokes shift. As for the two pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03b585415bb488684ae4122c0ac06b7f
https://doi.org/10.1016/j.snb.2019.02.078
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8
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells
Autor: Qi Wang, Feng Xiao, Haomiao Su, Hui Liu, Jinglei Xu, Heng Tang, Shanshan Qin, Zhentian Fang, Ziang Lu, Jian Wu, Xiaocheng Weng, Xiang Zhou
Publikováno v: Nucleic Acids Research. 50:e84-e84
The development of RNA aptamers/fluorophores system is highly desirable for understanding the dynamic molecular biology of RNAs in vivo. Peppers-based imaging systems have been reported and applied for mRNA imaging in living cells. However, the need
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f31f0dcce5259973dc44271059e16
https://doi.org/10.1093/nar/gkac368
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