Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhenshui Zhang"'
Autor:
Fei Yao, Jaya P. Kausalya, Yee Yen Sia, Audrey S.M. Teo, Wah Heng Lee, Alicia G.M. Ong, Zhenshui Zhang, Joanna H.J. Tan, Guoliang Li, Denis Bertrand, Xingliang Liu, Huay Mei Poh, Peiyong Guan, Feng Zhu, Thushangi Nadeera Pathiraja, Pramila N. Ariyaratne, Jaideepraj Rao, Xing Yi Woo, Shaojiang Cai, Fabianus H. Mulawadi, Wan Ting Poh, Lavanya Veeravalli, Chee Seng Chan, Seong Soo Lim, See Ting Leong, Say Chuan Neo, Poh Sum D. Choi, Elaine G.Y. Chew, Niranjan Nagarajan, Pierre-Étienne Jacques, Jimmy B.Y. So, Xiaoan Ruan, Khay Guan Yeoh, Patrick Tan, Wing-Kin Sung, Walter Hunziker, Yijun Ruan, Axel M. Hillmer
Publikováno v:
Cell Reports, Vol 12, Iss 2, Pp 272-285 (2015)
Genome rearrangements, a hallmark of cancer, can result in gene fusions with oncogenic properties. Using DNA paired-end-tag (DNA-PET) whole-genome sequencing, we analyzed 15 gastric cancers (GCs) from Southeast Asians. Rearrangements were enriched in
Externí odkaz:
https://doaj.org/article/02de0f8a47244f94862edfad662693ff
Autor:
Kagistia H Utami, Axel M Hillmer, Irene Aksoy, Elaine G Y Chew, Audrey S M Teo, Zhenshui Zhang, Charlie W H Lee, Pauline J Chen, Chan Chee Seng, Pramila N Ariyaratne, Sigrid L Rouam, Lim Seong Soo, Saira Yousoof, Ivan Prokudin, Gregory Peters, Felicity Collins, Meredith Wilson, Alyson Kakakios, Georges Haddad, Arnaud Menuet, Olivier Perche, Stacey Kiat Hong Tay, Ken W K Sung, Xiaoan Ruan, Yijun Ruan, Edison T Liu, Sylvain Briault, Robyn V Jamieson, Sonia Davila, Valere Cacheux
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e90852 (2014)
Delineating candidate genes at the chromosomal breakpoint regions in the apparently balanced chromosome rearrangements (ABCR) has been shown to be more effective with the emergence of next-generation sequencing (NGS) technologies. We employed a large
Externí odkaz:
https://doaj.org/article/f08ec6b361204c559748e2e486235dd1
Autor:
Fei Yao, Pramila N Ariyaratne, Axel M Hillmer, Wah Heng Lee, Guoliang Li, Audrey S M Teo, Xing Yi Woo, Zhenshui Zhang, Jieqi P Chen, Wan Ting Poh, Kelson F B Zawack, Chee Seng Chan, See Ting Leong, Say Chuan Neo, Poh Sum D Choi, Song Gao, Niranjan Nagarajan, Hervé Thoreau, Atif Shahab, Xiaoan Ruan, Valère Cacheux-Rataboul, Chia-Lin Wei, Guillaume Bourque, Wing-Kin Sung, Edison T Liu, Yijun Ruan
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46152 (2012)
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify gen
Externí odkaz:
https://doaj.org/article/002d58f95b314f93af5fa171994c4378
Autor:
Kah-Leong Lim, Cheng Wang, Norazean Zaiden, Shiam-Peng Tay, Han Seok Ko, Valina L. Dawson, Jeanne M.M. Tan, Zhenshui Zhang, Esther Wong, Ted M. Dawson
Publikováno v:
Journal of Biological Chemistry. 282:12310-12318
Loss of parkin function is a predominant cause of familial Parkinsonism. Emerging evidence also suggests that parkin expression variability may confer a risk for sporadic Parkinson disease. We have recently demonstrated that a wide variety of Parkins
Autor:
Zhenshui Zhang, Yue Wang
Publikováno v:
Microbiology. 146:2845-2854
rRNA genes are thought unlikely to be laterally transferred, because rRNA must coevolve with a large number of cellular components to form the highly sophisticated translation apparatus and perform protein synthesis. In this paper, the authors first
Publikováno v:
International Journal of Systematic Bacteriology. 46:933-938
We determined almost complete 16S rRNA gene sequences of two Microbispora bispora (Lechevalier 1965) strains, ATCC 19993T (T = type strain) and JCM 3082. The two sequences were 99% similar to each other but exhibited only 81 to 87.8% similarity with
Publikováno v:
International Journal of Systematic Bacteriology. 46:658-663
The 16S rRNA gene sequences of 7 Microbispora strains, 14 Microtetraspora species, 9 Streptosporangium species, and 12 Actinomadura species were determined. A phylogenetic analysis showed that Microtetraspora fusca, Microtetraspora glauca, and Microt
Autor:
Wan Ting Poh, Xiaoan Ruan, Chia-Lin Wei, Valere Cacheux-Rataboul, Yijun Ruan, Niranjan Nagarajan, Edison T. Liu, Wah Heng Lee, Kelson F B Zawack, Atif Shahab, See Ting Leong, Song Gao, Zhenshui Zhang, Xing Yi Woo, Chee Seng Chan, Fei Yao, Guillaume Bourque, Hervé Thoreau, Poh Sum D Choi, Pramila N. Ariyaratne, Axel M. Hillmer, Guoliang Li, Jieqi P. Chen, Audrey S.M. Teo, Wing-Kin Sung, Say Chuan Neo
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46152 (2012)
PLoS ONE
PLoS ONE
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. While genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify gen
Autor:
Valere Cacheux-Rataboul, Wing-Kin Sung, Per Hall, Edison T. Liu, Hao Zhao, Wan Ting Poh, Jonas Bergh, Kelson F B Zawack, Wah Heng Lee, Khay Guan Yeoh, Jimmy Bok Yan So, See Ting Leong, Xiaoan Ruan, Manuel Salto-Tellez, Guillaume Bourque, Yijun Ruan, Audrey S.M. Teo, Jieqi P. Chen, Zhenshui Zhang, Patrick Tan, Yee Yen Sia, Song Gao, Chia-Lin Wei, Chee Seng Chan, Pramila N. Ariyaratne, Feng Zhu, Vikrant Kumar, Xing Yi Woo, Koichiro Inaki, Fei Yao, Say Chuan Neo, Axel M. Hillmer, Guoliang Li, Poh Sum D Choi, Hui Ping J Lim, Hervé Thoreau, Leena Ukil, Niranjan Nagarajan, Atif Shahab
Publikováno v:
Genome research. 21(5)
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long-span paired-end-tag (PET) sequencing approach using 10-Kb genomic DNA inserts to study human genome structural variations (SVs). The use of a
Autor:
Andrew B. West, Valina L. Dawson, Saskia Biskup, Dustin Dikeman, Kah-Leong Lim, Darren J. Moore, Catherine Choi, Ted M. Dawson, Xiaojie Li, Zhenshui Zhang, Shaida A. Andrabi
Publikováno v:
Human molecular genetics. 16(2)
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) cause late-onset Parkinson's disease indistinguishable from idiopathic disease. The mechanisms whereby missense alterations in the LRRK2 gene initiate neurodegeneration remain unknown. Here,