Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Zhenquan Xuan"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesNumerous observational studies have reported associations between circulating cytokines and atopic dermatitis (AD); however, the causal relationships between them remain unclear. To explore the causal correlations and direction of causal ef
Externí odkaz:
https://doaj.org/article/cb43e124d22a41d9be40dc6ba149409f
Autor:
Qiyao Wang, Difan Zhang, Jiani Lu, Jiaying Zhang, Zhenquan Xuan, Luyun Gong, Mengxiang Yang, Lingli Jin, Jingyang Le, An Zhu, Hongze Liang, C. Benjamin Naman, Jinrong Zhang, Li Zhao, Shan He, Qinwen Wang, Hao Liu, Xiaojun Yan, Lingling Zhao, Wei Cui
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105359- (2022)
Fucoxanthin is the most abundant marine carotenoid derived from edible brown seaweeds and has been used as a functional ingredient for the treatment of obesity. However, poor brain bioavailability of fucoxanthin has limited its application in combati
Externí odkaz:
https://doaj.org/article/0456eb3817aa42cd83445eb2d047845b
Autor:
Yifan Han, Wei Cui, Yiying Zhou, Yanfei Xie, Karl Wah Keung Tsim, Xinmei Gu, Hui Zhang, Haibo Jin, Sicheng Yan, Marvin Mak, Dongsheng Zhou, Paul R. Carlier, Zhenquan Xuan, Shengquan Hu
Publikováno v:
ACS Chemical Neuroscience. 12:2462-2477
Alzheimer's disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, a multitarget-directed ligands (MTDLs) strategy has been developed to treat AD. We have previously designed and synthesized dimeric tacrine(10)-h
Autor:
Wei Cui, Yujing Bai, Panpan Zhang, Yushan Yan, Zhenquan Xuan, Hui Zhang, Yiying Zhou, Luying Ye, Yi Feng, Xiang Wu, Binbin Zhu, Yi Chen
Publikováno v:
Metabolic Brain Disease. 35:373-383
Postoperative cognitive dysfunction (POCD) is a common neurological disease affecting the elderly patients after surgery. Unfortunately, no effective treatment for this disease has been discovered. Edaravone, a clinical-used free radical scavenger, a
Autor:
Mengxiang Yang, Jinrong Zhang, Wei Cui, C. Benjamin Naman, Qiyao Wang, Xiaojun Yan, Sicheng Yan, Dongsheng Zhou, Shan He, Zhenquan Xuan
Publikováno v:
Nutritional neuroscience. 25(10)
Fucoxanthin, one of the most abundant carotenoids from edible brown seaweeds, for years has been used as a bioactive dietary supplement and functional food ingredient. Recently, fucoxanthin was reported to penetrate the blood-brain barrier, and was s
Autor:
Dongsheng Zhou, Yiying Zhou, Zhenquan Xuan, Paul R. Carlier, Haibo Jin, Wei Cui, Sicheng Yan, Shengquan Hu, Karl Wah Keung Tsim, Yifan Han, Yanfei Xie, Hui Zhang, Xingmei Gu, Marvin Shing-Hung Mak
Background Alzheimer’s disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, multi-target-directed ligands (MTDLs) strategy has been developed to combat this disease. We have previously designed and synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b114556c414e3d1cd101a72917a5bb6f
https://doi.org/10.21203/rs.3.rs-236543/v1
https://doi.org/10.21203/rs.3.rs-236543/v1
Autor:
Luying Jiang, Li Li, Wei Cui, Fuping Lu, Qinchen Dong, Fang Zhao, Fufeng Liu, Beibei Chen, Zhenquan Xuan, Wenjuan Wang
Publikováno v:
International journal of biological macromolecules. 170
Fast green FCF (FGF) is often used in foods, pharmaceuticals, and cosmetics. However, little is known about the interactions of FGF with amyloid-β protein (Aβ) associated with Alzheimer's disease. In this study, the inhibitory effects of FGF on Aβ
Autor:
Chen Xiaowei, Hongze Liang, Hui Zhang, Difan Zhang, Sicheng Yan, Zhenquan Xuan, Wei Cui, Yi Feng, Fei Zhou, Yuechun Mao, Xiaojun Yan, Xinghan Huang, Xiao Xiao, Hao Liu, Hanbo Pan, Bojun Chen
Publikováno v:
International Immunopharmacology. 97:107656
Objectives This study was aimed to investigate the neuroprotective effects of 9-methylfascaplysin, a novel marine derivative derived from sponge, against middle cerebral artery occlusion/reperfusion (MCAO)-induced motor impairments, neuroinflammation
Publikováno v:
International Immunopharmacology. 81:106263
Pathological β-amyloid (Aβ)-induced microglial activation could cause chronic neuroinflammation in the brain of Alzheimer's disease (AD) patients, and has been considered as one of the main pathological events of this disease. Chicago sky blue 6B (