Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Zhenqing, Feng"'
Autor:
Xuejun Xiao, Yan Peng, Zheyue Wang, Louqian Zhang, Tingting Yang, Yangyang Sun, Yufeng Chen, Wenqing Zhang, Xinxia Chang, Wen Huang, Shuning Tian, Zhenqing Feng, Nabi Xinhua, Qi Tang, Yuan Mao
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106269- (2022)
Background: Siglec-15 (S15) is a type-I transmembrane protein and is considered a new candidate of immune checkpoint inhibitor for cancer immunotherapy. Methods: In the present study, we first constructed and characterized a chimeric S15-specific mon
Externí odkaz:
https://doaj.org/article/4f986752e1014f1dbc9a7c9731e1849f
Autor:
Daolu Yang, Wenyan Feng, Yu Zhuang, Junxia Liu, Zhenqing Feng, Tianwei Xu, Wei Wang, Yefei Zhu, Zhaoxia Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 1053-1065 (2021)
Long non-coding RNAs (lncRNAs) can play significant regulatory roles in cells that affect the development and acquired drug resistance of lung cancer. Herein, we report that lncRNA linc00665 is significantly upregulated in non-small cell lung cancer
Externí odkaz:
https://doaj.org/article/6a15afa52dc841bea0643b69610e6745
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Desmoglein2 (DSG2) is a transmembrane protein that helps regulate intercellular connections and contributes to desmosome assembly. Desmosome are associated with cell adhesion junctions, which play an important role in cancer progr
Externí odkaz:
https://doaj.org/article/85e0102cc8ea4fdc911e0c9282839e28
Autor:
Furun An, Huiping Wang, Zhenyun Liu, Fan Wu, Jiakui Zhang, Qianshan Tao, Yingwei Li, Yuanyuan Shen, Yanjie Ruan, Qing Zhang, Ying Pan, Weiwei Zhu, Hui Qin, Yansheng Wang, Yongling Fu, Zhenqing Feng, Zhimin Zhai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
CAR T therapy has some efficacy in the treatment of patients with refractory/relapsed B-cell acute lymphoblastic leukemia; however in some patients further relapse is encountered. Here, the authors conduct a Phase II clinical trial of a CD19 CAR T an
Externí odkaz:
https://doaj.org/article/98edec5e9e1b40fba202ff27a9aef3a1
Autor:
Yuan Mao, Weifei Fan, Hao Hu, Louqian Zhang, Jerod Michel, Yaqin Wu, Jun Wang, Lizhou Jia, Xiaojun Tang, Li Xu, Yan Chen, Jin Zhu, Zhenqing Feng, Lin Xu, Rong Yin, Qi Tang
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background Cancer/testis antigens (CTAs) are a special type of tumor antigen and are believed to act as potential targets for cancer immunotherapy. Methods In this study, we first screened a rational CTA MAGE-A1 for lung adenocarcinoma (LUAD
Externí odkaz:
https://doaj.org/article/d61021188818443bb1412593a92dfb4a
Autor:
Qi Tang, Siping Xiong, Xudong Liang, Xingwang Kuai, Yiwen Wang, Changjun Wang, Zhenqing Feng, Jin Zhu
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Disease caused by Bacillus anthracis is often accompanied by high mortality primarily due to toxin-mediated injury. In the early disease course, anthrax toxins are secreted; thus, antibiotic use is limited to the early stage. In t
Externí odkaz:
https://doaj.org/article/f98f30d88aac4e1c924930ce0dbad4a6
Autor:
Wei Jiang, Tao Li, Jiaojiao Guo, Jingjing Wang, Lizhou Jia, Xiao shi, Tingting Yang, Ruonan Jiao, Xin Wei, Zhenqing Feng, Qi Tang, Guozhong Ji
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
T cells expressing chimeric antigen receptors, especially CD19 CAR-T cells have exhibited effective antitumor activities in B cell malignancies, but due to several factors such as antigen escape effects and tumor microenvironment, their curative pote
Externí odkaz:
https://doaj.org/article/f315b1d57ea2405d834a84ae04dab396
Autor:
Tingting, Yang, Lizhou, Jia, Susu, Bian, Xinxia, Chang, Qian, Zhang, Qi, Tang, Jing, Zhu, Zhiping, Yang, Zhenqing, Feng
Publikováno v:
Current Cancer Drug Targets. 22:691-702
Background: Gastric cancer (GC) is the fourth most commonly found cancer and the second- highest cause of cancer-related death worldwide. TROP2 overexpression is closely related to many cancers, including gastrointestinal tumors. DSG2 is an important
Autor:
Zhangyu, Yao, Xiang, Li, Jun, Gao, Yutao, Wang, Linmei, Xiao, Xinxia, Chang, Fangzhou, Liu, Zhenqing, Feng, Xiao, Zhang
Publikováno v:
Human Cell. 35:1464-1474
Disulfiram (DSF), which is an inhibitor of aldehyde dehydrogenase (ALDH) and approved by the FDA for the treatment of alcoholism previously, has been repurposed for use as a cancer treatment because of its potent effect in preclinical studies. In thi
Autor:
Yilan Ma, Mingjiong Zhang, Jiayan Wang, Xiaochen Huang, Xingwang Kuai, Xiaojuan Zhu, Yuan Chen, Lizhou Jia, Zhenqing Feng, Qi Tang, Zheng Liu
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Hepatocellular carcinoma (HCC) is one of the most mortality-causing solid cancers globally and the second largest cause of death among malignancies. Oxaliplatin, a platinum-based drug, has been widely utilized in the treatment of malignancies such as
Externí odkaz:
https://doaj.org/article/fbc5ebef1ae84152aefe4bcd92c929ba