Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Zhenqiang SUN"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Plenty of circRNAs have been reported to play an important role in colorectal cancer (CRC), while the reason of abnormal circRNA expression in cancer still keep elusive. Here, we found that m7G RNA modifications were enriched in some circRNA
Externí odkaz:
https://doaj.org/article/63421d25c240434598ccac31d9695305
Autor:
Jing Li, Xiaohong Xu, Kaihao Xu, Xueliang Zhou, Kunpeng Wu, Yuan Yao, Zaoqu Liu, Chen Chen, Ling Wang, Zhenqiang Sun, Dechao Jiao, Xinwei Han
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background Refractoriness to surgical resection and chemotherapy makes intrahepatic cholangiocarcinoma (ICC) a fatal cancer of the digestive system with high mortality and poor prognosis. Important function invests circRNAs with tremendous p
Externí odkaz:
https://doaj.org/article/ac6dfdd7a0064e519a03666cf202fd5a
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-21 (2024)
Abstract Although immunotherapy has made breakthrough progress, its efficacy in solid tumours remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver various intracellular molecules to adjacent or distant cells a
Externí odkaz:
https://doaj.org/article/4e0da7260cef48f6b733925174248976
Autor:
Wenkang Wang, Yang Liu, Zhen He, Lifeng Li, Senbo Liu, Mingqiang Jiang, Bing Zhao, Meng Deng, Wendong Wang, Xuefang Mi, Zhenqiang Sun, Xin Ge
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract As the latest and most anticipated method of tumor immunotherapy, CAR-NK therapy has received increasing attention in recent years, and its safety and high efficiency have irreplaceable advantages over CAR-T. Current research focuses on the
Externí odkaz:
https://doaj.org/article/7293f3ec17e342cbbc60a2058bd18a56
Autor:
Zhuang Chen, Qiming Wang, Jinbo Liu, Wenkang Wang, Weitang Yuan, Yang Liu, Zhenqiang Sun, Chengzeng Wang
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 176-188 (2024)
A pre-metastatic niche (PMN) is a protective microenvironment that facilitates the colonization of disseminating tumor cells in future metastatic organs. Extracellular vesicles (EVs) play a role in intercellular communication by delivering cargoes, s
Externí odkaz:
https://doaj.org/article/1dcb8dbf8d8e45e3bcbe972e11dd3824
Autor:
Ming Yue, Shengyun Hu, Haifeng Sun, Baojing Tuo, Bin Jia, Chen Chen, Wenkang Wang, Jinbo Liu, Yang Liu, Zhenqiang Sun, Junhong Hu
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-20 (2023)
Abstract Tumor immunotherapy has transformed neoplastic disease management, yet low response rates and immune complications persist as major challenges. Extracellular vesicles including exosomes have emerged as therapeutic agents actively involved in
Externí odkaz:
https://doaj.org/article/bb9ab1d5114f40d187b5cd1d17d873a9
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Tumor angiogenesis plays vital roles in the growth and metastasis of cancer. RNA methylation is one of the most common modifications and is widely observed in eukaryotes and prokaryotes. Accumulating studies have revealed that RNA methylatio
Externí odkaz:
https://doaj.org/article/f7b20aad493f4d6d96bbca89a521b22a
Autor:
Yang Liu, Chen Chen, Jinbo Liu, Zhenqiang Sun, Bo Shao, Yanxin Xu, Pengyuan Dang, Shengyun Hu, Haifeng Sun, Chaoguan Wang, Junhong Hu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Accumulating evidence demonstrates that an increased tumor-associated macrophage abundance is often associated with poor prognosis in colorectal cancer (CRC). The mechanism underlying the effect of tumor-derived exosomes on M2 macrophage p
Externí odkaz:
https://doaj.org/article/94cfc39da1df4f1a8f47058d40b421e7
Autor:
Senbo Liu, Wenkang Wang, Shengyun Hu, Bin Jia, Baojing Tuo, Haifeng Sun, Qiming Wang, Yang Liu, Zhenqiang Sun
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-19 (2023)
Abstract Cancer immunotherapy has transformed traditional treatments, with immune checkpoint blockade being particularly prominent. However, immunotherapy has minimal benefit for patients in most types of cancer and is largely ineffective in some can
Externí odkaz:
https://doaj.org/article/e54a5af3efc1445fa1911843bdaa55b8
Autor:
Zhuang Chen, Wenkang Wang, Shengyun Hu, Haifeng Sun, Chen Chen, Zhiyong Zhang, Xinzhi Sun, Bin Jia, Junhong Hu, Chengzeng Wang, Yang Liu, Zhenqiang Sun
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108779- (2024)
Summary: Immune escape is identified as one of the reasons for the poor prognosis of colorectal cancer (CRC) patients. Circular RNAs are considered to promote tumor progression by mediating tumor immune escape. We discovered that higher expression of
Externí odkaz:
https://doaj.org/article/4d3e8c79a35b4ec597722aa7fc81b8c4